dermosav plus cream - Uses, Price, Side Effects & Substitutes
What is dermosav plus cream used for?
Clobest-CM Cream (Ciprofloxacin + Metronidazole) is used to treat DERMA. It contains Ciprofloxacin (1% w/w) + Metronidazole (1% w/w), which Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Metronidazole . Always consult your doctor before use. Take as prescribed.
- Generic Name: Ciprofloxacin + Metronidazole
- Manufacturer: Bennet Mypher Pharmaceuticals LLP
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ dermosav plus cream Uses & Benefits
Topical treatment of infected wounds, ulcers, and skin infections with mixed aerobic/anaerobic flora
Off-label uses: Pressure ulcers, Diabetic foot ulcers
๐ Drug Information
| Generic Name(s) | Ciprofloxacin + Metronidazole |
| Brand Name | Clobest-CM Cream |
| Manufacturer | Bennet Mypher Pharmaceuticals LLP |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Topical |
| Storage | Store at 20-25ยฐC; protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV; Metronidazole disrupts DNA synthesis in anaerobic bacteria and protozoa
Mechanism Steps
๐ก How to Take dermosav plus cream
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of dermosav plus cream
โ Common Side Effects
- Application site irritation
- Itching
- Redness
๐จ Serious Side Effects
- Severe allergic reaction
- Tendon rupture (rare with topical)
โ ๏ธ Rare Side Effects
- Peripheral neuropathy
- Disulfiram-like reaction with alcohol
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Tizanidine | Major | Hypotension, sedation |
| Theophylline | Major | Increased theophylline levels, toxicity |
| NSAIDs | Moderate | Increased CNS stimulation risk |
| Oral hypoglycemics | Moderate | Hypoglycemia risk |
| Corticosteroids | Moderate | Increased tendon rupture risk |
| Caffeine | Minor | Reduced caffeine clearance |
| Antacids (systemic) | Minor | Reduced ciprofloxacin absorption (if oral) |
๐จ Major Interactions
- Warfarin
- Tizanidine
- Theophylline
โก Moderate Interactions
- NSAIDs
- Oral hypoglycemics
- Corticosteroids
โน๏ธ Minor Interactions
- Caffeine
- Antacids (systemic)
๐ฝ๏ธ Food Interactions
No significant food interactions for topical use
๐ท Alcohol Interaction
Avoid alcohol during metronidazole therapy (disulfiram-like reaction)
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to quinolones or metronidazole; application to open wounds or mucous membranes
๐ Monitoring Parameters
Local skin reactions, signs of superinfection
๐คฑ Lactation Safety
Caution; avoid application to breast area
๐ Overdose Management
Unlikely with topical use; if ingested, symptomatic treatment
โฐ Missed Dose
Apply as soon as remembered; skip if almost time for next dose