dermacare soap - Clindamycin (NA) medicine

dermacare soap

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Clindamycin (NA)
🏭 Psychotropics India Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is dermacare soap used for?

This medicine contains Clindamycin (NA) and is used to treat ANTI INFECTIVES. Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit, preventing peptide bond fo. Always consult your doctor before use.

  • Generic Name: Clindamycin
  • Manufacturer: Psychotropics India Ltd
  • Form: Allopathy
  • Pregnancy Category: Category B
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 dermacare soap Uses & Benefits

Treatment of acne vulgaris.

Off-label uses: Bacterial vaginosis (topical), Perioral dermatitis

📋 Drug Information

Generic Name(s)Clindamycin
Brand NameAcnesol Gel
ManufacturerPsychotropics India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassLincosamides
Route of AdministrationTopical
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionApproximately 10% of topically applied clindamycin is absorbed systemically.
DistributionDistributes widely into body tissues and fluids, including bone, but not significantly into cerebrospinal fluid.
Protein BindingAbout 93-94% bound to plasma proteins.
MetabolismHepatic metabolism to active and inactive metabolites.
Half-LifeApproximately 2-3 hours (topical absorption minimal).
ExcretionPrimarily renal (10% unchanged, rest as metabolites) and biliary.
BioavailabilityLow systemic bioavailability after topical application (<10%).
Onset of ActionWithin a few days to weeks of regular application.
Peak Plasma TimeNot applicable for topical use; minimal systemic absorption.
Duration of ActionSustained antibacterial effect on skin for up to 12 hours.

How It Works

Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit, preventing peptide bond formation.

Mechanism Steps

1Clindamycin binds to the 50S ribosomal subunit of bacteria.
2Inhibits peptide bond formation by blocking the peptidyl transferase activity.
3Prevents bacterial protein synthesis, leading to bacteriostatic effect.
4Reduces population of Propionibacterium acnes and decreases inflammation.

💡 How to Take dermacare soap

Follow your doctor's prescription exactly.

⚠️ Side Effects of dermacare soap

✅ Common Side Effects

Skin dryness
Peeling
Itching
Erythema
Burning sensation

🚨 Serious Side Effects

Pseudomembranous colitis
Severe allergic reactions
Stevens-Johnson syndrome

⚠️ Rare Side Effects

Contact dermatitis
Urticaria
Angioedema

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Erythromycin Major Antagonism of antibacterial effect
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Warfarin Moderate Increased INR and bleeding risk
Oral contraceptives Moderate Reduced contraceptive efficacy
Kaolin Minor Reduced absorption of clindamycin
Aluminum-containing antacids Minor Reduced absorption of clindamycin

🚨 Major Interactions

  • Erythromycin
  • Neuromuscular blocking agents

⚡ Moderate Interactions

  • Warfarin
  • Oral contraceptives

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to clindamycin or lincomycin; history of antibiotic-associated colitis.

🤱 Lactation Safety

Caution; not known if excreted in breast milk after topical use.

💊 Overdose Management

Topical overdose unlikely; if ingested, symptomatic and supportive care.

⏰ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

🔄 Substitutes for dermacare soap

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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