depranil 25mg tablet - Uses, Price, Side Effects & Substitutes
What is depranil 25mg tablet used for?
Antidep (Imipramine) is used to treat NEURO CNS. It contains Imipramine (25mg), which Inhibits reuptake of norepinephrine and serotonin at presynaptic neuronal membra. Always consult your doctor before use. Take as prescribed.
- Generic Name: Imipramine
- Manufacturer: La Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ depranil 25mg tablet Uses & Benefits
Major depressive disorder, nocturnal enuresis in children, panic disorder, chronic pain.
Off-label uses: ADHD, bulimia nervosa, migraine prophylaxis, postherpetic neuralgia.
๐ Drug Information
| Generic Name(s) | Imipramine |
| Brand Name | Antidep |
| Manufacturer | La Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Tricyclic antidepressants |
| Route of Administration | Oral. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits reuptake of norepinephrine and serotonin at presynaptic neuronal membrane, increasing their concentrations in the synaptic cleft.
Mechanism Steps
๐ก How to Take depranil 25mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of depranil 25mg tablet
โ Common Side Effects
- Dry mouth
- Constipation
- Blurred vision
- Drowsiness
- Dizziness
- Weight gain
๐จ Serious Side Effects
- QT prolongation
- Arrhythmias
- Seizures
- Suicidal thoughts
- Serotonin syndrome
โ ๏ธ Rare Side Effects
- Agranulocytosis
- Hepatotoxicity
- Paralytic ileus
- Angle-closure glaucoma
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis, hyperpyrexia, convulsions |
| Warfarin | Moderate | Increased anticoagulant effect |
| Alcohol | Moderate | Increased sedation and CNS depression |
๐จ Major Interactions
- MAOIs
- CYP2D6 inhibitors
- CYP1A2 inhibitors
- CYP2C19 inhibitors
- CYP3A4 inhibitors
โก Moderate Interactions
- Anticholinergics
- CNS depressants
- Antihypertensives
- Sympathomimetics
โน๏ธ Minor Interactions
- Cimetidine
- Fluoxetine
- Paroxetine
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase levels; avoid alcohol.
๐ท Alcohol Interaction
Increased CNS depression and sedation.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, recent MI, concurrent MAOI use, narrow-angle glaucoma, urinary retention.
๐ Monitoring Parameters
ECG, blood pressure, liver function tests, serum drug levels, mental status.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
Supportive care; activated charcoal, ECG monitoring, sodium bicarbonate for arrhythmias, flumazenil not effective.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for depranil 25mg tablet
View AllAlternative brands with exact same active ingredient (Imipramine (25mg)):
-
imipra 25mg tabletCyril Pharmaceuticals โน5.90 27.9% CHEAPER
-
impramine 25mg tabletSun Pharmaceutical Industries Ltd โน7.00 14.4% CHEAPER
-
imprin 25mg tabletOsho Pharma Pvt Ltd โน7.00 14.4% CHEAPER
-
imikon 25mg tabletKonark Lifesciences Pvt Ltd โน7.00 14.4% CHEAPER
-
eldep 25mg tabletPsychotropics India Ltd โน8.00 2.2% CHEAPER
-
elidep 25mg tabletElite Pharma Pvt Ltd โน8.00 2.2% CHEAPER
-
antipres 25mg tabletPsycormedies โน8.20 0.2% COSTLIER
-
depsin 25mg tabletSynokem Pharmaceuticals Ltd โน8.20 0.2% COSTLIER
-
hemidap 25mg tabletHema Laboratories โน8.40 2.7% COSTLIER
-
shimin 25mg tabletShine Pharmaceuticals Ltd โน8.50 3.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.