deklot 5mg tablet - Prasugrel (5mg) medicine

Deklot 5mg Tablet (Prasugrel): Complete Medicine Guide

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🏭 Grownbury Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding that does not stop

If experiencing severe symptoms, call emergency services immediately.

What is deklot 5mg tablet used for?

This medicine contains Prasugrel 5 mg, an antiplatelet agent used to prevent blood clots in patients with acute coronary syndrome who have undergone percutaneous coronary intervention. It works by irreversibly blocking the P2Y12 receptor on platelets, reducing the risk of heart attack, stroke, and stent thrombosis. It is a prescription medicine and must be taken exactly as directed by a doctor.

  • Generic Name: Prasugrel (5mg)
  • Manufacturer: Grownbury Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 deklot 5mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा प्रसुग्रेल 5 मिलीग्राम की एक एंटीप्लेटलेट गोली है। यह उन मरीजों के लिए दी जाती है जिन्हें दिल का दौरा पड़ा हो या अस्थिर एनजाइना हुआ हो और जिनकी एंजियोप्लास्टी या स्टेंट की प्रक्रिया हुई हो। यह खून में थक्का बनने से रोकती है, जिससे दिल का दौरा, स्ट्रोक और स्टेंट ब्लॉकेज का खतरा कम होता है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए और डॉक्टर की सलाह के बिना बंद नहीं करनी चाहिए।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नाक से खून आना, आसानी से चोट लगना या नील पड़ना, मसूड़ों से खून आना, सिरदर्द, पीठ दर्द, जी मिचलाना और दस्त शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में खून बहना, मस्तिष्क में खून बहना, और बहुत कम मामलों में थ्रोम्बोटिक थ्रोम्बोसाइटोपेनिक पुरपुरा हो सकता है। अगर आपको काला या खून वाला मल, खून की उल्टी, तेज सिरदर्द, या शरीर पर अचानक नील पड़ना दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खासकर स्टेंट लगने के बाद इसे अपने आप बंद न करें, क्योंकि इससे स्टेंट में खून का थक्का बन सकता है जो जानलेवा हो सकता है। कोई भी सर्जरी, दांत का इलाज या प्रक्रिया से पहले अपने डॉक्टर को बताएं कि आप यह दवा ले रहे हैं। बिना डॉक्टर की सलाह के दर्द निवारक दवाएं जैसे आइबुप्रोफेन या एस्पिरिन न लें। शराब से बचें क्योंकि इससे खून बहने का खतरा बढ़ सकता है। दवा को कमरे के तापमान पर, नमी और धूप से दूर, बच्चों की पहुंच से बाहर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 deklot 5mg tablet Uses & Benefits

[{"condition":"Acute coronary syndrome managed with percutaneous coronary intervention","description":"This medicine is used to reduce the risk of thrombotic cardiovascular events, including stent thrombosis, in patients with acute coronary syndrome who are undergoing percutaneous coronary intervention.","evidence":"Well-established"},{"condition":"Secondary prevention after myocardial infarction","description":"It may be continued long-term in some patients after a heart attack to prevent recurrent cardiovascular events, as part of dual antiplatelet therapy.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Prevention of thromboembolic events in other high-risk vascular conditions","description":"In some cases, specialists may consider this medicine for other conditions where platelet inhibition is desired, but this is not a standard approved use.","evidence":"Limited"}]

Primary treatment for: Acute coronary syndrome

Also treats: Myocardial infarction, Unstable angina, Coronary artery disease with stent placement

📋 Drug Information

Generic Name(s)Prasugrel (5mg)
Brand Namedeklot 5mg tablet
ManufacturerGrownbury Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassP2Y12 inhibitors (ADP receptor)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, away from moisture and direct sunlight. Do not refrigerate.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time every day to maintain a steady level in your body.
2
Do not stop this medicine without consulting your doctor, especially if you have a stent.
3
Inform your doctor or dentist about this medicine before any procedure or surgery.
4
Watch for signs of bleeding such as bruising, nosebleeds, or bleeding gums, and report them to your doctor.
5
Avoid alcohol and NSAIDs like ibuprofen while taking this medicine to reduce bleeding risk.
6
If you miss a dose, take it as soon as you remember, but do not double the dose.
7
Keep all your follow-up appointments so your doctor can monitor your progress and adjust treatment if needed.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Recent heart attack or stent placement
This medicine is commonly prescribed in this situation.
Likely Use
❌
Chronic joint pain
This medicine is not a painkiller.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPrasugrel is rapidly absorbed after oral administration. It is a prodrug and its absorption is not significantly affected by food. The active metabolite reaches peak levels quickly.
DistributionThe active metabolite of Prasugrel is highly bound to plasma proteins, mainly albumin and alpha-1 acid glycoprotein. It distributes into body tissues, but detailed volume of distribution data are not established from the available information.
Protein BindingApproximately 98% of the active metabolite is bound to plasma proteins.
MetabolismPrasugrel is extensively metabolized in the liver. It is first converted to an intermediate by carboxylesterases, and then to the active metabolite by cytochrome P450 enzymes, primarily CYP3A4 and CYP2B6. The active metabolite is further metabolized to inactive compounds.
Half-LifeThe elimination half-life of the active metabolite is approximately 7 hours, but the antiplatelet effect lasts much longer because of irreversible binding to platelets.
ExcretionPrasugrel and its metabolites are excreted mainly in the urine and feces. About 68% of the dose is excreted in urine and about 27% in feces.
BioavailabilityThe absolute bioavailability of Prasugrel is not established from the available information, but it is rapidly and extensively absorbed.
Onset of ActionAfter a loading dose, the antiplatelet effect begins within 30 minutes to 1 hour, with maximum inhibition achieved within 2 to 4 hours.
Peak Plasma TimePeak plasma concentration of the active metabolite occurs approximately 30 minutes after oral administration.
Duration of ActionThe antiplatelet effect lasts for the lifespan of the platelet, which is about 7 to 10 days after the last dose.

How It Works

This medicine works by irreversibly blocking the P2Y12 adenosine diphosphate receptor on the surface of platelets. Prasugrel is a prodrug that must be converted by liver enzymes into its active metabolite. Once active, it binds permanently to the P2Y12 receptor, preventing adenosine diphosphate from activating the platelet. This stops the activation of glycoprotein IIb/IIIa receptors, which are needed for platelets to clump together. As a result, platelet aggregation is inhibited for the entire lifespan of the platelet, which is about 7 to 10 days. This effect reduces the formation of blood clots in coronary arteries and stents.

Mechanism Steps

1
Prodrug activation: Prasugrel is a prodrug that is rapidly converted by liver enzymes, mainly CYP3A4 and CYP2B6, into its active metabolite.
2
P2Y12 receptor binding: The active metabolite irreversibly binds to the P2Y12 adenosine diphosphate receptor on the platelet surface.
3
Blockade of ADP signaling: By blocking the receptor, adenosine diphosphate cannot activate the platelet through this pathway.
4
Inhibition of glycoprotein IIb/IIIa activation: Without P2Y12 signaling, the glycoprotein IIb/IIIa receptor remains inactive, so fibrinogen cannot cross-link platelets.
5
Reduced platelet aggregation: The final result is strong inhibition of platelet clumping and clot formation, which lasts for the life of the platelet.

💡 How to Take deklot 5mg tablet

Strength: Prasugrel 5 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food.
4Do not crush, chew, or break the tablet unless your doctor tells you to.
5Take it at the same time each day to help you remember.
6Do not stop taking this medicine without talking to your doctor first.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 mg or 10 mg taken once daily, depending on the patient's weight, age, and other medicines. A loading dose may be given at the start of treatment, but this must be determined by a qualified clinician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and bleeding risk. Do not change the dose without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be at higher risk of bleeding. The dose should be individualized by a qualified clinician, and lower doses may be considered.
Renal ImpairmentNo dose adjustment is required for mild to moderate kidney impairment. In severe kidney impairment, use with caution and individualize the dose as advised by a qualified clinician.
Hepatic ImpairmentNo dose adjustment is required for mild to moderate liver impairment. This medicine is contraindicated in severe liver disease (Child-Pugh Class C).
Maximum Daily DoseThe maximum recommended daily dose is 10 mg, but the exact dose must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid large amounts
May affect liver enzymes that activate the medicine.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of deklot 5mg tablet

✅ Common Side Effects

Bleeding (nosebleeds, bruising, bleeding gums) (Common (5-10%))
Apply pressure to stop bleeding. If bleeding is prolonged or severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult your doctor if it persists or is severe.
Back pain (Common (5-10%))
Rest and use gentle heat. If pain is severe or persistent, consult your doctor.
Nausea (Common (5-10%))
Take with food if it helps. Consult your doctor if nausea is persistent.
Diarrhea (Common (5-10%))
Stay hydrated. Consult your doctor if diarrhea is severe or lasts more than a few days.

🚨 Serious Side Effects

Severe bleeding (gastrointestinal, intracranial, or other sites) (Uncommon (0.1-1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, severe headache, confusion, or any bleeding that does not stop.
Thrombotic thrombocytopenic purpura (TTP) (Rare (<0.1%))
Seek immediate medical attention if you develop fever, unusual bruising, confusion, or yellowing of the skin or eyes.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.

⚠️ Rare Side Effects

Thrombotic thrombocytopenic purpura
Seek immediate medical attention if you have fever, bruising, confusion, or jaundice.
Severe liver injury
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ibuprofen Major
Naproxen Major
Ketoconazole Moderate
Clarithromycin Moderate
Rifampin Moderate
Carbamazepine Moderate
Omeprazole Minor
SSRIs Major
SNRIs Major

🚨 Major Interactions

  • Warfarin and other anticoagulants
  • NSAIDs (e.g., ibuprofen, naproxen)
  • SSRIs and SNRIs

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal bleeding and should be avoided or limited while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active pathological bleeding","History of stroke or transient ischemic attack","Severe liver disease (Child-Pugh Class C)","Known hypersensitivity to Prasugrel or any component of the tablet"]

⚠️ Warnings & Precautions

["This medicine increases the risk of bleeding. Use with caution in patients at high risk of bleeding.","Do not stop this medicine without talking to your doctor, especially if you have a stent.","Inform your doctor if you have a history of bleeding disorders, recent surgery, or trauma.","Use with caution in elderly patients, who may have a higher risk of bleeding.","Avoid concurrent use with other anticoagulants or antiplatelet agents unless specifically prescribed.","Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

It is not known whether Prasugrel is excreted in human breast milk. Because many medicines are excreted in breast milk, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.

💊 Overdose Management

Overdose may cause severe bleeding. There is no specific antidote for Prasugrel. In case of overdose, seek emergency medical attention immediately. Treatment is supportive, and platelet transfusion may be considered if bleeding is severe.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it on your own, especially after stent placement, because stopping too early can lead to stent thrombosis, which is a life-threatening emergency. Inform all healthcare providers, including dentists and surgeons, that you are taking this medicine before any procedure. Avoid activities that increase the risk of injury or bleeding. Do not take other blood thinners, pain relievers such as aspirin or ibuprofen, or herbal supplements without asking your doctor first. If you miss a dose, follow your doctor's instructions; do not double the dose. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have a higher risk of bleeding. The dose should be individualized, and lower doses may be considered. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, talk to your doctor before starting or continuing this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine increases bleeding risk during and after surgery. Inform your surgeon that you are taking this medicine. Your doctor may advise you to stop it temporarily before surgery, but never stop without medical advice.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. You may bleed more than usual. Your dentist may consult your doctor about temporarily stopping the medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Eat a balanced diet rich in fruits, vegetables, and whole grains.
😴
Avoid smoking and limit alcohol consumption.
💧
Engage in regular physical activity as advised by your doctor.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep to support heart health.

🏋️ Exercise Considerations

Avoid contact sports or activities that increase the risk of injury and bleeding. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like fish
Reduce processed and high-fat foods
Stay well hydrated
Limit alcohol intake

💼 Impact on Daily Work & Life

This medicine may increase bleeding risk, so avoid activities that could cause injury. It is generally safe to drive, but if you experience dizziness or vision changes, avoid driving until you feel better.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your doctor will decide when it is safe to stop, usually after a specified duration of dual antiplatelet therapy. Stopping early can be dangerous.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of bleeding. Regular monitoring for signs of bleeding and blood tests may be needed. It is important to continue the medicine for the duration recommended by your doctor, as stopping early can increase the risk of heart attack or stent thrombosis. Your doctor will assess the benefits and risks periodically.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Clopidogrel

Another antiplatelet medicine that may be used if Prasugrel is not suitable.

Evidence: Well-established
Ticagrelor

Another antiplatelet medicine that may be used as an alternative.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions known. However, inform your healthcare provider that you are taking this medicine before receiving any vaccine, especially if it involves injections.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If crossing time zones, continue taking your dose at the same interval as prescribed; consult your doctor if you are unsure. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man who had a heart attack and received a stent
He was prescribed this medicine along with aspirin after his procedure. He initially felt fine and wanted to stop the medicine, but his doctor explained that stopping early could cause a dangerous clot in the stent. He continued the medicine as directed and attended regular follow-ups. He did experience some bruising, but no serious bleeding.
💡 Lesson: It is crucial to continue antiplatelet therapy exactly as prescribed after stent placement, even if you feel well.
👤 A 65-year-old woman with a history of stomach ulcers
She was started on this medicine after a heart attack. Her doctor also prescribed a stomach-protecting medicine because of her ulcer history. She was advised to avoid ibuprofen and alcohol. She reported mild nausea initially, which improved after taking the tablet with food.
💡 Lesson: Patients with a history of ulcers need gastroprotection and should avoid other medicines that increase bleeding risk.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 30 to 60 minutes after a loading dose, with maximum effect in 2 to 4 hours. The antiplatelet effect lasts for 7 to 10 days after stopping.

Q: Can I stop taking this medicine if I feel better?

A: No, you should not stop this medicine without talking to your doctor, especially if you have a stent. Stopping early can lead to a life-threatening clot.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for deklot 5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once you feel better.
    Fact: No, stopping this medicine early, especially after stent placement, can cause a life-threatening clot in the stent. Always follow your doctor's instructions.
  • Myth: This medicine is a painkiller.
    Fact: No, this medicine is an antiplatelet agent. It does not relieve pain; it prevents blood clots.
  • Myth: It is safe to take aspirin with this medicine without asking a doctor.
    Fact: No, combining this medicine with aspirin or other blood thinners can increase bleeding risk. Only take them together if prescribed.

🔄 Alternative Options

Generic Alternatives

  • Prasugrel 5 mg tablet

Brand Alternatives

  • Deklot 5mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Prasugrel","class":"P2Y12 inhibitor","onset":"30-60 minutes","duration":"7-10 days","note":"Irreversible binding."},{"medicine":"Clopidogrel","class":"P2Y12 inhibitor","onset":"2-4 hours","duration":"7-10 days","note":"Irreversible binding, prodrug."},{"medicine":"Ticagrelor","class":"P2Y12 inhibitor","onset":"30 minutes","duration":"3-5 days","note":"Reversible binding."}]

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