Dehydroepiandrosterone (Micronized) (75mg) + Folic Acid (5mg) + Vitamin D3 (3000IU) (Medical Monograph)

Overview

A fixed-dose combination supplement containing micronized Dehydroepiandrosterone (DHEA), a prohormone precursor to androgens and estrogens; Folic Acid, a synthetic form of Vitamin B9; and Vitamin D3 (Cholecalciferol). This combination is primarily targeted at addressing age-related hormonal decline, supporting energy, mood, bone health, and cardiovascular wellness in the Indian adult population, particularly in perimenopausal women and men with andropause symptoms. The micronization of DHEA enhances its bioavailability.

Uses

  • Management of age-related decline in DHEA levels (Adrenopause)
  • Nutritional supplementation in adults with deficiencies of Vitamin D and Folic Acid
  • Support for bone health and prevention of osteoporosis in at-risk individuals

Side Effects

  • Acne, oily skin
  • Mild gastrointestinal upset (nausea, bloating)
  • Headache
  • Insomnia (if taken late in the day)

Detailed Pharmacology

DHEA serves as a precursor for the synthesis of androgens (testosterone) and estrogens (estradiol) in peripheral tissues, exerting pleiotropic effects. Folic Acid acts as a cofactor in one-carbon metabolism for DNA synthesis, repair, and methylation. Vitamin D3 regulates calcium-phosphate homeostasis and exerts genomic effects via the Vitamin D Receptor (VDR).

Available Brands in India

BrandManufacturerPrice
DHEA Gold Plus Cipla Limited ₹1200 - ₹1500 for 10 tablets
RegeneVate-D Sun Pharmaceutical Industries Ltd. ₹1100 - ₹1400 for 10 capsules
Vitalong-D Dr. Reddy's Laboratories ₹1300 - ₹1600 for 10 tablets
AndroVita Forte Mankind Pharma Ltd. ₹1000 - ₹1300 for 10 capsules