defmind 50mg tablet - Desvenlafaxine (50mg) medicine

defmind 50mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Brainwave Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is defmind 50mg tablet used for?

D-Veniz 50 Tablet ER (Desvenlafaxine) is used to treat NEURO CNS. It contains Desvenlafaxine (50mg), which Inhibits serotonin and norepinephrine reuptake (SNRI).. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Desvenlafaxine
  • Manufacturer: Brainwave Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š defmind 50mg tablet Uses & Benefits

Major depressive disorder (MDD).

Off-label uses: Anxiety disorders, Panic disorder, Social anxiety disorder, Neuropathic pain, Vasomotor symptoms of menopause

๐Ÿ“‹ Drug Information

Generic Name(s)Desvenlafaxine
Brand NameD-Veniz 50 Tablet ER
ManufacturerBrainwave Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSerotonin-norepinephrine reuptake inhibitors (SNRIs)
Route of AdministrationOral (extended-release tablet).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; food does not affect absorption.
DistributionDistributed throughout the body; volume of distribution approximately 3.4 L/kg.
Protein Binding30% bound to plasma proteins.
MetabolismPrimarily metabolized by conjugation (UGT isoforms) and to a lesser extent by CYP3A4.
Half-LifeApproximately 11 hours.
ExcretionApproximately 45% excreted unchanged in urine; 19% as glucuronide conjugate.
BioavailabilityApproximately 80%.
Onset of ActionMay take 1-2 weeks for therapeutic effect.
Peak Plasma TimeAbout 7.5 hours (extended-release formulation).
Duration of Action24 hours (once-daily dosing).

How It Works

Inhibits serotonin and norepinephrine reuptake (SNRI).

Mechanism Steps

1Desvenlafaxine binds to SERT and NET, inhibiting reuptake of serotonin and norepinephrine.
2Increased synaptic concentrations of serotonin and norepinephrine enhance neurotransmission.
3Downregulation of postsynaptic receptors over time contributes to antidepressant effect.

๐Ÿ’ก How to Take defmind 50mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of defmind 50mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Anxiety
  • Increased sweating
  • Insomnia
  • Constipation
  • Decreased appetite
  • Sexual dysfunction
  • Dizziness
  • Somnolence

๐Ÿšจ Serious Side Effects

  • Serotonin syndrome
  • Suicidal thoughts or behaviors
  • Increased blood pressure
  • Angle-closure glaucoma
  • Seizures
  • Hyponatremia

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Stevens-Johnson syndrome
  • Pancreatitis
  • Hepatitis
  • Rhabdomyolysis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased risk of serotonin syndrome
Linezolid Major Increased risk of serotonin syndrome
Methylene blue Major Increased risk of serotonin syndrome
SSRIs Moderate Additive serotonergic effects, risk of serotonin syndrome
SNRIs Moderate Additive serotonergic effects, risk of serotonin syndrome
Triptans Moderate Additive serotonergic effects, risk of serotonin syndrome
Lithium Moderate Increased risk of serotonin syndrome
Tramadol Moderate Increased risk of serotonin syndrome
St. John's Wort Moderate Increased risk of serotonin syndrome
Warfarin Moderate Increased bleeding risk
NSAIDs Moderate Increased bleeding risk
Aspirin Moderate Increased bleeding risk
Cimetidine Minor May increase desvenlafaxine levels
CYP3A4 inhibitors Minor May increase desvenlafaxine levels

๐Ÿšจ Major Interactions

  • MAOIs
  • Linezolid
  • Methylene blue

โšก Moderate Interactions

  • SSRIs
  • SNRIs
  • Triptans
  • Lithium
  • Tramadol
  • St. John's Wort
  • Warfarin
  • NSAIDs
  • Aspirin

โ„น๏ธ Minor Interactions

  • Cimetidine
  • CYP3A4 inhibitors

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase CNS depression and risk of adverse effects.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to desvenlafaxine or any excipients; concomitant use with MAOIs or within 14 days of MAOI discontinuation.

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, signs of serotonin syndrome, suicidal ideation, mood changes.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Symptomatic and supportive care; monitor ECG, vital signs; consider activated charcoal if recent ingestion.

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for defmind 50mg tablet

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Alternative brands with exact same active ingredient (Desvenlafaxine (50mg)):

Medical Note: Always consult your doctor before switching medications.

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