deca-arodec 25mg injection - Nandrolone Decanoate (25mg) medicine

Metadec 25 Injection: Complete Guide to Uses, Dosage, and Safety

No reviews yet
🏭 Willow Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not recommended. This medicine is contraindicated in pregnancy due to risk of fetal harm, including virilization of female fetus. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain
  • Chest pain or shortness of breath
  • Swelling in legs or ankles
  • Sudden severe headache or vision changes
  • Prolonged painful erection
  • Blood in urine or stool

If experiencing severe symptoms, call emergency services immediately.

What is deca-arodec 25mg injection used for?

This medicine is an anabolic steroid injection used to treat anemia in kidney disease, osteoporosis in postmenopausal women, and wasting conditions. It works by stimulating red blood cell production and protein synthesis. It is given intramuscularly every 3-4 weeks under medical supervision.

  • Generic Name: Nandrolone Decanoate (25mg)
  • Manufacturer: Willow Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 deca-arodec 25mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा नैंड्रोलोन डेकानोएट का इंजेक्शन है, जिसका उपयोग किडनी रोग से जुड़े एनीमिया, महिलाओं में ऑस्टियोपोरोसिस, और वजन घटाने वाली बीमारियों के इलाज के लिए किया जाता है। यह मांसपेशियों और हड्डियों की वृद्धि को बढ़ावा देती है और लाल रक्त कोशिकाओं का उत्पादन बढ़ाती है। यह इंजेक्शन डॉक्टर द्वारा मांसपेशी में लगाया जाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, सूजन, मुँहासे, और शरीर पर बाल बढ़ना शामिल हैं। पुरुषों में स्तन वृद्धि और वीर्य उत्पादन में कमी हो सकती है। महिलाओं में आवाज भारी हो सकती है। गंभीर दुष्प्रभावों में लिवर की समस्या, दिल की बीमारी, और रक्त के थक्के बनना शामिल हैं।

सुरक्षा सलाह: यह दवा केवल डॉक्टर की देखरेख में ही लगवाएँ। खुद से इंजेक्शन न लगाएँ। शराब का सेवन न करें। गर्भावस्था में इसका उपयोग न करें। नियमित रूप से लिवर और किडनी की जाँच कराएँ। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएँ।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 deca-arodec 25mg injection Uses & Benefits

[{"condition":"Anemia of chronic kidney disease","description":"Stimulates erythropoiesis and improves hemoglobin levels in patients with kidney failure.","evidence":"Well-established"},{"condition":"Postmenopausal osteoporosis","description":"Helps increase bone mineral density and reduce fracture risk in women with osteoporosis.","evidence":"Well-established"},{"condition":"Wasting syndrome (e.g., HIV/AIDS, cancer)","description":"Promotes weight gain and muscle mass in patients with catabolic conditions.","evidence":"Moderate"},{"condition":"Hereditary angioedema","description":"May reduce frequency of attacks by increasing C1 esterase inhibitor levels.","evidence":"Limited"}]

Off-label uses: [{"condition":"Male hypogonadism","description":"Sometimes used off-label for testosterone replacement, but not first-line.","evidence":"Limited"},{"condition":"Athletic performance enhancement","description":"Illicit use for muscle building; not a medical indication and illegal.","evidence":"Not established"}]

Primary treatment for: Anemia of chronic kidney disease

Also treats: Postmenopausal osteoporosis, Wasting syndrome, Hereditary angioedema

📋 Drug Information

Generic Name(s)Nandrolone Decanoate (25mg)
Brand Namedeca-arodec 25mg injection
ManufacturerWillow Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassAnabolic steroid
Route of AdministrationParenteral (intramuscular injection)
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only under medical supervision; do not self-inject.
2
Monitor liver function tests regularly during treatment.
3
Assess cardiovascular risk before starting and during therapy.
4
In women, watch for signs of virilization and discontinue if they occur.
5
In men, monitor for testicular atrophy and decreased libido.
6
Ensure adequate calcium and vitamin D intake for bone health.
7
Avoid alcohol to reduce liver toxicity risk.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Anemia
This medicine is commonly prescribed for anemia of chronic kidney disease.
Likely Use
✅
Osteoporosis
This medicine is used for postmenopausal osteoporosis.
Likely Use
✅
Weight loss
This medicine is used for wasting syndrome.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNandrolone decanoate is administered intramuscularly and is absorbed slowly from the injection site due to its esterified formulation. Peak plasma concentrations are typically reached within 3 to 7 days after injection.
DistributionNandrolone is highly bound to plasma proteins and distributes widely into tissues, with a volume of distribution of approximately 1.5 L/kg. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 80% bound to plasma proteins, primarily to sex hormone-binding globulin (SHBG) and albumin.
MetabolismNandrolone decanoate is hydrolyzed by esterases in the liver and other tissues to release free nandrolone, which is then further metabolized by hepatic enzymes, primarily CYP3A4, to inactive metabolites.
Half-LifeThe elimination half-life of nandrolone decanoate is approximately 6 to 12 days after intramuscular injection.
ExcretionMetabolites are excreted primarily in the urine, with a small amount in feces.
BioavailabilityNot established from the available information.
Onset of ActionAnabolic effects may begin within 1 to 2 weeks, but clinical benefits such as increased hemoglobin or bone density may take several weeks to months.
Peak Plasma Time3 to 7 days after intramuscular injection.
Duration of ActionThe effects of a single injection can last for 2 to 3 weeks.

How It Works

Nandrolone decanoate is a synthetic anabolic-androgenic steroid that binds to cytoplasmic androgen receptors in target tissues such as muscle, bone, and kidney. Upon binding, the receptor-ligand complex translocates to the nucleus and modulates gene transcription, leading to increased protein synthesis, nitrogen retention, and erythropoietin production. It also suppresses gonadotropin secretion via negative feedback on the pituitary, reducing endogenous testosterone production.

Mechanism Steps

1
Binding to androgen receptor: Nandrolone decanoate binds to the androgen receptor in the cytoplasm of target cells.
2
Receptor translocation: The drug-receptor complex moves into the nucleus and binds to specific DNA sequences.
3
Gene transcription: This binding alters the transcription of genes involved in protein synthesis, erythropoiesis, and bone metabolism.
4
Anabolic effects: Increased protein synthesis leads to muscle growth, weight gain, and improved nitrogen balance.
5
Erythropoietic effect: Stimulation of erythropoietin production increases red blood cell mass.

💡 How to Take deca-arodec 25mg injection

Strength: Injection: 25 mg/mL

1This medicine is administered by a healthcare professional as an intramuscular injection.
2The injection is typically given into the gluteal muscle.
3Do not self-administer.
4Follow your doctor's schedule for injections.
5Attend regular follow-up appointments for monitoring.

Dosage Information

Adult DosageThe usual adult dose is 25-50 mg intramuscularly every 3-4 weeks for anemia of chronic kidney disease, or 50 mg every 3 weeks for postmenopausal osteoporosis. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to fluid retention and cardiovascular effects. Use with caution and monitor closely.
Renal ImpairmentNo specific dose adjustment is established, but use with caution in patients with renal impairment due to risk of fluid retention.
Hepatic ImpairmentContraindicated in severe liver disease. Use with caution in mild to moderate hepatic impairment; monitor liver function.
Maximum Daily DoseNot applicable as it is given every 3-4 weeks. Maximum single dose should not exceed 100 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing required for injection
This medicine is injected, not taken orally.
Alcohol
Avoid
Increases risk of liver toxicity.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of deca-arodec 25mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the area. Consult doctor if pain persists.
Acne (Common (5-10%))
Keep skin clean. Consult a dermatologist if severe.
Fluid retention (Common (5-10%))
Reduce salt intake. Inform doctor if swelling worsens.
Increased facial/body hair (Common (5-10%))
Cosmetic measures may help. Consult doctor if bothersome.

🚨 Serious Side Effects

Liver toxicity (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Cardiovascular events (e.g., heart attack, stroke) (Rare (<0.1%))
Call emergency services if you experience chest pain, shortness of breath, or sudden weakness.
Blood clots (Rare (<0.1%))
Seek immediate care if you have swelling, pain, or redness in a limb, or difficulty breathing.

⚠️ Rare Side Effects

Priapism
Seek emergency medical attention if you have a prolonged painful erection.
Hepatocellular carcinoma
Report any persistent abdominal pain or jaundice to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Insulin Major
Corticosteroids Moderate
Cyclosporine Moderate

🚨 Major Interactions

  • Warfarin
  • Insulin and oral hypoglycemics

⚡ Moderate Interactions

  • Corticosteroids
  • Cyclosporine

🍷 Alcohol Interaction

Avoid alcohol consumption while using this medicine as it can increase the risk of liver damage and worsen fluid retention.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy or breastfeeding","Known hypersensitivity to nandrolone or any component","Male breast cancer or prostate cancer","Severe liver disease","Nephrotic syndrome","Hypercalcemia"]

⚠️ Warnings & Precautions

["May cause virilization in women; monitor for signs.","Can suppress endogenous testosterone production; monitor in men.","May worsen sleep apnea; use with caution.","Can cause fluid retention; caution in heart failure.","May increase risk of blood clots; use with caution in patients with thrombophilia.","Not for use in children; may cause premature epiphyseal closure."]

🤱 Lactation Safety

Not recommended. It is excreted in breast milk and may cause adverse effects in the nursing infant.

💊 Overdose Management

Overdose is unlikely with intramuscular administration. In case of accidental overdose, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, contact your healthcare provider to reschedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

This medicine must only be administered by a healthcare professional. Do not self-inject. Regular monitoring of liver function, blood counts, and lipid profile is essential. Avoid alcohol as it increases liver stress. Inform your doctor if you have heart, kidney, or liver disease. Do not use if you are pregnant or planning pregnancy. Report any unusual swelling, difficulty breathing, or chest pain immediately. Do not share this medicine with others. Keep out of reach of children. Follow your doctor's instructions exactly regarding dose and frequency.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to fluid retention and cardiovascular effects. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated in pregnancy and should not be used by women planning to conceive. Discuss alternative treatments with your doctor.

🏥 Post-Surgery Considerations

Inform your surgeon if you are on this medicine as it may affect wound healing and increase risk of blood clots. It may need to be stopped before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine as it may increase bleeding risk during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Avoid smoking and excessive alcohol.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience fluid retention or joint pain. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Limit sodium to manage fluid retention

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue; avoid driving or operating heavy machinery until you know how it affects you. It may also affect mood and energy levels.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects, seek immediate medical attention. Your doctor will determine if and when to discontinue based on your condition and response.

📅 Long-Term Use Effects

Long-term use can lead to liver toxicity, cardiovascular complications, and suppression of natural testosterone production. Regular monitoring of liver function, lipid profile, and blood counts is essential. Use should be reviewed periodically to assess benefit versus risk.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Erythropoiesis-stimulating agents (ESAs)

Can be used for anemia of chronic kidney disease.

Evidence: Well-established
Bisphosphonates

Alternative for osteoporosis management.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light. If traveling across time zones, consult your doctor about adjusting injection timing. Declare it at customs if required.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old woman with postmenopausal osteoporosis
She received this medicine every 3 weeks as prescribed. After 6 months, her bone density improved, and she experienced fewer back pains. She reported mild acne but no serious side effects.
💡 Lesson: Regular injections and monitoring can lead to improved bone health with manageable side effects.
👤 A 45-year-old man with anemia of chronic kidney disease
He was started on this medicine to improve his hemoglobin. After 2 months, his hemoglobin levels rose, and he felt more energetic. He experienced some fluid retention, which was managed with dietary changes.
💡 Lesson: This medicine can effectively treat anemia in kidney disease, but fluid retention requires monitoring.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Anabolic effects may begin within 1-2 weeks, but clinical benefits such as increased hemoglobin or bone density may take several weeks to months.

Q: How is this medicine given?

A: It is given as an intramuscular injection by a healthcare professional, usually every 3-4 weeks.

Q: What are the serious side effects?

A: Serious side effects include liver toxicity, cardiovascular events, and blood clots. Seek immediate medical attention if you experience symptoms like jaundice, chest pain, or swelling.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for deca-arodec 25mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Metadec 25 injection is a safe way to build muscle.
    Fact: This medicine is a controlled substance with serious side effects and should only be used under medical supervision for approved indications.
  • Myth: Metadec 25 injection is safe during pregnancy.
    Fact: It is contraindicated in pregnancy as it can harm the fetus.

🔄 Alternative Options

Generic Alternatives

  • Nandrolone decanoate injection (generic)

Brand Alternatives

  • Deca-Durabolin
  • Metadec 50

📊 Comparison with Similar Medicines

[{"medicine":"Nandrolone decanoate","class":"Anabolic steroid","half_life":"6-12 days","route":"Intramuscular"},{"medicine":"Testosterone enanthate","class":"Anabolic steroid","half_life":"4-5 days","route":"Intramuscular"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory