davaindia amlodipine+atenolol 5mg/25mg tablet - Amlodipine (5mg) + Atenolol (25mg) medicine

davaindia amlodipine+atenolol 5mg/25mg tablet

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🏭 Davaindia Generic Pharmacy 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is davaindia amlodipine+atenolol 5mg/25mg tablet used for?

This medicine contains Amlodipine (5mg) + Atenolol (25mg) and is used to treat CARDIAC. Amlodipine inhibits calcium influx across cell membranes in vascular smooth muscle and cardiac muscl. Always consult your doctor before use.

  • Generic Name: Amlodipine + Atenolol
  • Manufacturer: Davaindia Generic Pharmacy
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 davaindia amlodipine+atenolol 5mg/25mg tablet Uses & Benefits

Hypertension, angina pectoris (chronic stable angina, vasospastic angina)

Off-label uses: None known

📋 Drug Information

Generic Name(s)Amlodipine + Atenolol
Brand NameAmlokind-AT Tablet
ManufacturerDavaindia Generic Pharmacy
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blocker + Beta blocker
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F), protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmlodipine: Well absorbed after oral administration; Atenolol: Incompletely absorbed (about 50%)
DistributionAmlodipine: Large volume of distribution; Atenolol: Low volume of distribution, minimal CNS penetration
Protein BindingAmlodipine: ~93%; Atenolol: <5%
MetabolismAmlodipine: Extensive hepatic metabolism via CYP3A4; Atenolol: Minimal hepatic metabolism
Half-LifeAmlodipine: 30-50 hours; Atenolol: 6-7 hours
ExcretionAmlodipine: 60% urine (10% unchanged), 20-25% feces; Atenolol: Primarily renal (unchanged)
BioavailabilityAmlodipine: 64-90%; Atenolol: ~50%
Onset of ActionAmlodipine: 2-4 hours; Atenolol: 1-2 hours
Peak Plasma TimeAmlodipine: 6-12 hours; Atenolol: 2-4 hours
Duration of ActionAmlodipine: 24 hours; Atenolol: 12-24 hours

How It Works

Amlodipine inhibits calcium influx across cell membranes in vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced peripheral resistance. Atenolol selectively blocks beta-1 adrenergic receptors, decreasing heart rate, contractility, and cardiac output.

Mechanism Steps

1Amlodipine binds to L-type calcium channels in vascular smooth muscle and cardiac muscle.
2Inhibits calcium influx, leading to relaxation of vascular smooth muscle (vasodilation) and reduced peripheral vascular resistance.
3Decreases myocardial oxygen demand by afterload reduction.
4Atenolol selectively blocks beta-1 adrenergic receptors in the heart.
5Reduces heart rate, myocardial contractility, and cardiac output.
6Decreases renin release from kidneys, further lowering blood pressure.
7Combined effect: synergistic reduction in blood pressure and antianginal efficacy.

💡 How to Take davaindia amlodipine+atenolol 5mg/25mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of davaindia amlodipine+atenolol 5mg/25mg tablet

✅ Common Side Effects

Edema (ankle/foot)
Headache
Dizziness
Fatigue
Nausea
Flushing
Palpitations
Bradycardia
Cold extremities

🚨 Serious Side Effects

Severe hypotension
Heart failure exacerbation
Bradyarrhythmias
Bronchospasm
Hepatotoxicity (rare)
Stevens-Johnson syndrome (rare)

⚠️ Rare Side Effects

Gingival hyperplasia
Leukopenia
Thrombocytopenia
Vasculitis
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major Increased risk of bradycardia, heart block, and hypotension
Clonidine Major Rebound hypertension upon clonidine withdrawal
NSAIDs Moderate Reduced antihypertensive effect
Grapefruit juice Minor Increased amlodipine levels

🚨 Major Interactions

  • Beta blockers (other)
  • Calcium channel blockers (verapamil, diltiazem)
  • CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir)
  • Clonidine
  • Digitalis glycosides

⚡ Moderate Interactions

  • NSAIDs
  • Antihypertensives (additive effect)
  • Insulin
  • Oral hypoglycemics
  • Anesthetics

🍷 Alcohol Interaction

Alcohol may enhance hypotensive effect; avoid excessive alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to components, cardiogenic shock, severe bradycardia, heart block (2nd/3rd degree), sick sinus syndrome, severe hypotension, acute heart failure, asthma/COPD (atenolol), peripheral vascular disease (severe)

🤱 Lactation Safety

Low risk; both drugs excreted in breast milk in small amounts. Caution advised.

💊 Overdose Management

Supportive care; atropine for bradycardia, vasopressors for hypotension, calcium gluconate for calcium channel blocker overdose, glucagon for beta blocker overdose

⏰ Missed Dose

Take as soon as remembered if within 12 hours; skip if close to next dose. Do not double dose.

🔄 Substitutes for davaindia amlodipine+atenolol 5mg/25mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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