Amtas-AT Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Chest pain that worsens or is not relieved by rest
- Shortness of breath or difficulty breathing
- Swelling of the face, lips, tongue, or throat
- Very slow or irregular heartbeat
- Yellowing of the skin or eyes
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is amlokos at 5mg/25mg tablet used for?
This medicine is a combination of Amlodipine and Atenolol used to treat high blood pressure and angina. It works by relaxing blood vessels and slowing the heart rate.
- Generic Name: Amlodipine + Atenolol
- Manufacturer: Raptakos Brett & Co Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 amlokos at 5mg/25mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह उन वयस्कों के लिए है जिनका रक्तचाप एक दवा से नियंत्रित नहीं होता। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, पैरों में सूजन, धीमी हृदय गति और हाथ-पैर ठंडे होना शामिल हैं। ये आमतौर पर हल्के होते हैं और समय के साथ कम हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको गंभीर चक्कर, बेहोशी, सांस लेने में कठिनाई या दिल की धड़कन बहुत धीमी लगे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, खासकर यदि आपको एंजाइना है। शराब का सेवन न करें क्योंकि इससे चक्कर और निम्न रक्तचाप बढ़ सकता है। यदि आपको अस्थमा, मधुमेह, गुर्दे या यकृत की बीमारी है तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप, हृदय गति और गुर्दे की कार्यप्रणाली की जांच कराएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।
💊 amlokos at 5mg/25mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine effectively lowers blood pressure in adults with essential hypertension, reducing the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"It reduces the frequency and severity of angina attacks by decreasing cardiac workload and improving blood flow to the heart.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, though evidence is limited.","evidence":"Limited"},{"condition":"Anxiety with palpitations","description":"Beta-blockers like atenolol may be used off-label to manage anxiety-related palpitations.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Coronary artery disease
📋 Drug Information
| Generic Name(s) | Amlodipine + Atenolol |
| Brand Name | Amlokind-AT Tablet |
| Manufacturer | Raptakos Brett & Co Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + Beta blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, causing relaxation of peripheral arterioles and reducing peripheral vascular resistance. Atenolol is a cardioselective beta-1 adrenergic blocker that reduces heart rate, myocardial contractility, and cardiac output. Together, they lower blood pressure and decrease myocardial oxygen demand, which helps in angina.
Mechanism Steps
💡 How to Take amlokos at 5mg/25mg tablet
Strength: Tablet containing Amlodipine 5 mg and Atenolol 25 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and bradycardia. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, atenolol clearance is reduced. Dose adjustment may be necessary. Monitor renal function regularly. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | In patients with hepatic impairment, amlodipine clearance is reduced. Start with a lower dose and monitor closely. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of Amlodipine 5 mg + Atenolol 25 mg. Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of amlokos at 5mg/25mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| NSAIDs | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Verapamil or diltiazem
- Clonidine
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
⚡ Moderate Interactions
- NSAIDs
- Diabetes medications
- Digoxin
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, and increased risk of falls. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe aortic stenosis","Hypersensitivity to amlodipine or atenolol"]
⚠️ Warnings & Precautions
["Do not stop abruptly, especially in patients with angina, as it may worsen.","Use with caution in patients with asthma or COPD.","May mask symptoms of hypoglycemia in diabetics.","Use with caution in patients with renal or hepatic impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine."]
🤱 Lactation Safety
Amlodipine and atenolol are excreted in breast milk. Atenolol may accumulate in breastfed infants and cause bradycardia. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternatives.
💊 Overdose Management
Overdose may cause severe hypotension, bradycardia, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and symptomatic, including activated charcoal, IV fluids, vasopressors, and atropine for bradycardia. Dialysis may be considered for atenolol removal.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it abruptly, especially if you have angina, as this can worsen your condition. Avoid alcohol while taking this medicine as it may increase dizziness and low blood pressure. Inform your doctor if you have asthma, diabetes, kidney or liver disease, or any heart condition. Do not use potassium supplements without consulting your doctor. Regular monitoring of blood pressure, heart rate, and kidney function is advised. If you are pregnant or planning to become pregnant, consult your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to dizziness, bradycardia, and falls. Start with a lower dose and monitor closely. Regular assessment of renal function is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect heart rate and blood pressure during surgery. Your doctor may advise temporary discontinuation.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may affect blood pressure and heart rate during dental procedures. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is beneficial, but avoid sudden strenuous activities. If you experience chest pain, dizziness, or shortness of breath during exercise, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with dose adjustment.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your doctor decides to discontinue, they will gradually reduce the dose to prevent rebound effects.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups should include blood pressure, heart rate, kidney function, and liver function tests. Prolonged use may lead to tolerance or need for dose adjustment. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help control blood pressure and may reduce medication needs.
Evidence: Well-establishedACE inhibitors, ARBs, or thiazide diuretics may be alternatives if this combination is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The blood pressure-lowering effect begins within a few hours, but full effect may take 1 to 2 weeks of regular use.
A: No, you should not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause serious complications.
A: If you remember within 12 hours, take it as soon as possible. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for amlokos at 5mg/25mg tablet
View AllAlternative brands with exact same active ingredient:
-
betacard-am 5mg/25mg tabletTorrent Pharmaceuticals Ltd ₹6.09 67.6% CHEAPER
-
davaindia amlodipine+atenolol 5mg/25mg tabletDavaindia Generic Pharmacy ₹8.00 57.5% CHEAPER
-
numlo-at 5mg/25mg tabletEmcure Pharmaceuticals Ltd ₹13.35 29.1% CHEAPER
-
atamo 5mg/25mg tabletFinecure Pharmaceuticals Ltd. ₹17.00 9.7% CHEAPER
-
dipinol 5 mg/25 mg tabletGRAF Laboratories Pvt Ltd ₹24.38 29.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause rebound hypertension or angina. - Myth: This medicine is safe during pregnancy.
Fact: It is not recommended during pregnancy as it may harm the fetus. Consult your doctor for alternatives.
🔄 Alternative Options
Generic Alternatives
- Amlodipine 5 mg + Atenolol 25 mg tablet (generic)
Brand Alternatives
- Amlopres-AT
- Aten-A
- Amlokind-AT
- Amlong-A
- Stamlo Beta