Afdiex 5mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe hypoglycemia with confusion, seizures, or loss of consciousness
- Signs of allergic reaction such as rash, swelling of face or throat, or difficulty breathing
- Unusual bruising or bleeding
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
- Persistent nausea, vomiting, or diarrhea
- Decreased urine output or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is daomide tablet used for?
This medicine is a sulfonylurea antidiabetic tablet containing glibenclamide 5 mg. It is used to treat type 2 diabetes by stimulating the pancreas to release more insulin. It is taken orally once daily with breakfast. It can cause low blood sugar, so regular monitoring and meal timing are important.
- Generic Name: Glibenclamide (5mg)
- Manufacturer: Elixir Life Care Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 daomide tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज (मधुमेह) के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में इंसुलिन का स्तर बढ़ाकर ब्लड शुगर को कंट्रोल करती है। इसे आमतौर पर नाश्ते के साथ दिन में एक बार लिया जाता है। यह उन लोगों के लिए नहीं है जिन्हें टाइप 1 डायबिटीज है या कीटोएसिडोसिस है। इस दवा को लेते समय खाना नहीं छोड़ना चाहिए क्योंकि इससे ब्लड शुगर कम हो सकती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में ब्लड शुगर कम होना (हाइपोग्लाइसीमिया), जी मिचलाना, पेट में परेशानी, दस्त और वजन बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में गंभीर हाइपोग्लाइसीमिया, एलर्जी, खून की बीमारियां और लिवर की समस्या हो सकती है। अगर आपको कंपकंपी, पसीना, भ्रम या बेहोशी महसूस हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खाना न छोड़ें क्योंकि इससे ब्लड शुगर कम हो सकती है। हमेशा अपने पास ग्लूकोज या मिठाई रखें। शराब न पिएं क्योंकि इससे गंभीर हाइपोग्लाइसीमिया हो सकता है। अपनी ब्लड शुगर नियमित रूप से जांचें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं।
💊 daomide tablet Uses & Benefits
[{"condition":"Type 2 diabetes mellitus","description":"Used as an add-on to diet and exercise to lower blood sugar in adults with type 2 diabetes.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Gestational diabetes","description":"Sometimes considered in specific situations, but insulin is generally preferred.","evidence":"Limited"}]
Primary treatment for: Type 2 diabetes mellitus
Also treats: Metabolic syndrome, Obesity
📋 Drug Information
| Generic Name(s) | Glibenclamide (5mg) |
| Brand Name | daomide tablet |
| Manufacturer | Elixir Life Care Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylureas (Insulin Secretogogues) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine lowers blood sugar by closing ATP-sensitive potassium channels on pancreatic beta cells. This causes the cell membrane to depolarize, which opens voltage-gated calcium channels. The resulting calcium influx triggers the release of insulin from stored granules. It also increases the sensitivity of peripheral tissues to insulin.
Mechanism Steps
💡 How to Take daomide tablet
Strength: This medicine is available as a 5 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual starting dose of this medicine is 2.5 to 5 mg once daily, taken with breakfast or the first main meal. The dose may be increased gradually based on blood sugar response, up to a maximum of 20 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the blood sugar-lowering effect and are at higher risk of hypoglycemia. Start with a low dose and titrate slowly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Monitor blood sugar closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Monitor liver function and blood sugar. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 20 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of daomide tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Beta-blockers | Major | |
| Alcohol | Major | |
| Warfarin | Major | |
| Miconazole | Major | |
| Thiazide diuretics | Moderate | |
| Corticosteroids | Moderate | |
| ACE inhibitors | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Beta-blockers
- Alcohol
- Warfarin
- Miconazole
⚡ Moderate Interactions
- Diuretics (thiazides)
- Corticosteroids
- ACE inhibitors
🍷 Alcohol Interaction
Alcohol can increase the risk of severe hypoglycemia and may cause a disulfiram-like reaction with flushing, nausea, and vomiting. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Type 1 diabetes mellitus","Diabetic ketoacidosis","Severe renal impairment","Severe hepatic impairment","Known hypersensitivity to glibenclamide or sulfonylureas","Pregnancy and breastfeeding"]
⚠️ Warnings & Precautions
["Risk of hypoglycemia, especially with skipped meals, alcohol, or exercise.","Use with caution in elderly patients and those with renal or hepatic impairment.","May cause weight gain.","Not for use in type 1 diabetes or diabetic ketoacidosis.","Avoid in pregnancy and breastfeeding.","May interact with many other medicines; always inform your doctor."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may cause hypoglycemia in the nursing infant. It is not recommended during breastfeeding. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose can cause severe hypoglycemia. If overdose is suspected, seek emergency medical attention immediately. Treatment includes intravenous glucose and monitoring of blood sugar and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip meals while taking this medicine because skipping meals increases the risk of low blood sugar. Carry a fast-acting sugar source such as glucose tablets or candy with you at all times. Check your blood sugar regularly as advised. Avoid alcohol because it can cause dangerous low blood sugar. Tell your doctor about all other medicines you take, especially beta-blockers, diuretics, and other diabetes medicines. Do not drive or operate heavy machinery if you feel shaky, dizzy, or confused. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of hypoglycemia due to reduced kidney function and other medicines. Start with a low dose and monitor blood sugar closely.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning pregnancy, consult your doctor to switch to insulin or another safe alternative before conception.
🏥 Post-Surgery Considerations
After surgery, blood sugar control may be affected. Your doctor will adjust your diabetes medicines accordingly. Do not take this medicine without medical advice during the perioperative period.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. Dental procedures can affect your ability to eat, which may increase the risk of low blood sugar. Plan your meals and medicine timing accordingly.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise can lower blood sugar. Check your blood sugar before exercising and carry a fast-acting sugar source. Adjust your medicine dose or snack as advised by your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause low blood sugar, which can affect your ability to drive or operate machinery. Do not drive if you feel shaky, dizzy, or confused. Inform your employer about your condition and treatment.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping suddenly can cause high blood sugar. Your doctor may stop it if you develop severe side effects, kidney or liver problems, or if your treatment plan changes.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to weight gain and increased risk of hypoglycemia. Regular monitoring of blood sugar, kidney function, and liver function is recommended. It may also lose effectiveness over time, requiring dose adjustment or addition of other medicines.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
First-line medicine for type 2 diabetes, often used instead of or with sulfonylureas.
Evidence: Well-establishedMay be needed if oral medicines are not enough.
Evidence: Well-establishedDiet and exercise are essential for managing diabetes.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, infections can affect blood sugar control. Keep vaccinations up to date as advised by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Keep enough supply for the entire trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood sugar within 30 to 60 minutes after taking it. However, it may take several days to weeks to see the full effect on your blood sugar levels.
A: This medicine should be used with caution in kidney disease. Your doctor may adjust the dose and monitor your kidney function closely.
A: These are signs of low blood sugar. Eat or drink something sugary immediately, such as glucose tablets, candy, or fruit juice. If symptoms persist, seek medical help.
🤔 Common Patient Concerns
🔄 Substitutes for daomide tablet
View AllAlternative brands with exact same active ingredient:
-
betanase 5mg tabletCadila Pharmaceuticals Ltd ₹3.73 61.1% CHEAPER
-
gliconil 5mg tabletBiochem Pharmaceutical Industries ₹3.83 60.1% CHEAPER
-
codica 5mg tabletAbbott ₹4.41 54.1% CHEAPER
-
afdiex 5mg tabletCadila Pharmaceuticals Ltd ₹4.66 51.5% CHEAPER
-
davaindia glibenclamide 5mg tabletDavaindia Generic Pharmacy ₹5.00 47.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps control blood sugar but does not cure diabetes. It must be continued as prescribed. - Myth: I can eat anything while taking this medicine.
Fact: Diet and exercise are essential for controlling diabetes. This medicine works best when combined with a healthy lifestyle. - Myth: This medicine is safe for everyone with diabetes.
Fact: It is not suitable for people with type 1 diabetes, diabetic ketoacidosis, or severe kidney/liver disease.
🔄 Alternative Options
Generic Alternatives
- Glibenclamide 5 mg tablet
Brand Alternatives
- Afdiex 5mg Tablet