daktarin gel

4.7 (13 reviews)

Miconazole (2% w/w)

🏭 Janssen Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is daktarin gel used for?

Conzole-M Cream (Miconazole) is used to treat DERMA. It contains Miconazole (2% w/w), which Inhibits fungal cytochrome P450 14α-demethylase, blocking ergosterol synthesis . Always consult your doctor before use. Take as prescribed.

Generic Name: Miconazole
Manufacturer: Janssen Pharmaceuticals
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 daktarin gel Uses & Benefits

Topical treatment of fungal skin infections including tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and pityriasis versicolor.

Off-label uses: Treatment of seborrheic dermatitis, Treatment of oral thrush (oral gel formulation)

📋 Drug Information

Generic Name(s)	Miconazole
Brand Name	Conzole-M Cream
Manufacturer	Janssen Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	DERMA
Action Class	Fungal ergosterol synthesis inhibitor
Route of Administration	Topical.
Storage	Store at 20-25°C (68-77°F); keep tube tightly closed.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application; approximately 1-2% absorbed through intact skin.

DistributionDistributed mainly in the skin layers; negligible systemic distribution.

Protein BindingApproximately 88-93% bound to plasma proteins (if absorbed).

MetabolismHepatic metabolism via oxidative pathways; minimal due to low systemic absorption.

Half-LifeTopical: not applicable; systemic half-life ~24 hours if absorbed.

ExcretionPrimarily feces (via bile) and urine as metabolites.

BioavailabilityNegligible systemic bioavailability after topical application.

Onset of ActionWithin 24-48 hours for symptomatic relief.

Peak Plasma TimeNot applicable for topical use.

Duration of ActionSustained effect with regular application; treatment typically 2-4 weeks.

How It Works

Inhibits fungal cytochrome P450 14α-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.

Mechanism Steps

1Miconazole enters fungal cell via diffusion.

2Binds to fungal cytochrome P450 14α-demethylase (CYP51).

3Inhibits conversion of lanosterol to ergosterol.

💡 How to Take daktarin gel

Follow your doctor's prescription exactly.

⚠️ Side Effects of daktarin gel

✅ Common Side Effects

Burning
Stinging
Irritation
Itching
Redness at application site

🚨 Serious Side Effects

Allergic contact dermatitis
Angioedema
Anaphylaxis (rare)

⚠️ Rare Side Effects

Bullous dermatitis
Urticaria
Skin discoloration

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased INR and bleeding risk (systemic absorption may enhance anticoagulant effect).
Oral hypoglycemics	Major	Enhanced hypoglycemic effect (rare with topical use).
Phenytoin	Major	Increased phenytoin levels (rare with topical use).
Cisapride	Moderate	Risk of QT prolongation (theoretical, low systemic absorption).
Pimozide	Moderate	Risk of QT prolongation (theoretical).
Quinidine	Moderate	Risk of QT prolongation (theoretical).

🚨 Major Interactions

Warfarin
Oral hypoglycemics
Phenytoin

⚡ Moderate Interactions

Cisapride
Pimozide
Quinidine

ℹ️ Minor Interactions

Antacids
H2 antagonists
Proton pump inhibitors

🍽️ Food Interactions

No significant food interactions for topical use.

🍷 Alcohol Interaction

No known interaction with topical use.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to miconazole or any component; avoid use on broken or inflamed skin.

📊 Monitoring Parameters

Clinical improvement of skin lesions; monitor for signs of irritation or allergic reaction.

🤱 Lactation Safety

Likely safe; minimal systemic absorption; avoid application to breast area.

💊 Overdose Management

Overdose unlikely with topical use; if ingested, symptomatic and supportive care.

⏰ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for daktarin gel

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Alternative brands with exact same active ingredient (Miconazole (2% w/w)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

daktarin gel

What is daktarin gel used for?

💊 daktarin gel Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take daktarin gel

⚠️ Side Effects of daktarin gel

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for daktarin gel

⭐ User Reviews

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