blisderm ointment - Halobetasol (0.05% w/w) medicine

Blisderm Ointment (Halobetasol 0.05% w/w) - Uses, Price, Side Effects

4.2 (9 reviews)
๐Ÿญ Janssen Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is blisderm ointment used for?

Blisderm Ointment contains Halobetasol 0.05% w/w, a potent topical corticosteroid used to reduce inflammation, itching, and redness associated with skin conditions like psoriasis and eczema. It works by suppressing the immune response and inhibiting inflammatory mediators, providing relief from symptoms.

  • Generic Name: Halobetasol
  • Manufacturer: Janssen Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š blisderm ointment Uses & Benefits

Treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses (e.g., psoriasis, eczema).

Off-label uses: Lichen planus, Discoid lupus erythematosus

๐Ÿ“‹ Drug Information

Generic Name(s)Halobetasol
Brand NameBlisderm Ointment
ManufacturerJanssen Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassGlucocorticoids
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption varies; increased by inflamed skin or occlusion.
DistributionDistributes locally; minimal systemic absorption.
Protein BindingApproximately 90% bound to plasma proteins.
MetabolismMetabolized in the liver via CYP450 enzymes.
Half-LifeApproximately 5-6 hours (systemic).
ExcretionPrimarily renal (urine) and biliary (feces).
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionWithin a few days of regular application.
Peak Plasma TimeNot well-defined for topical use.
Duration of ActionDuration of effect persists for several hours after application.

How It Works

Binds to glucocorticoid receptors, modulating gene expression to reduce inflammation.

Mechanism Steps

1Penetrates the stratum corneum and binds to glucocorticoid receptors in target cells.
2Receptor-ligand complex translocates to the nucleus.
3Modulates gene transcription, increasing anti-inflammatory proteins (e.g., lipocortin-1) and decreasing pro-inflammatory mediators (e.g., cytokines, prostaglandins).

๐Ÿ’ก How to Take blisderm ointment

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of blisderm ointment

โœ… Common Side Effects

  • Burning
  • Itching
  • Irritation
  • Dryness

๐Ÿšจ Serious Side Effects

  • Skin atrophy
  • Striae
  • Telangiectasia
  • Systemic corticosteroid effects

โš ๏ธ Rare Side Effects

  • Allergic contact dermatitis
  • Hypertrichosis
  • Hypopigmentation

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Corticosteroids (systemic) Moderate Increased risk of systemic effects
Other topical corticosteroids Moderate Additive effects, increased skin thinning

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors
  • Other corticosteroids

โšก Moderate Interactions

  • Antidiabetic agents
  • Antihypertensives

โ„น๏ธ Minor Interactions

  • NSAIDs
  • Vaccines

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category C

๐Ÿšซ Contraindications

Hypersensitivity to halobetasol or any component; untreated bacterial, fungal, or viral infections.

๐Ÿ“Š Monitoring Parameters

Monitor for skin atrophy, signs of systemic absorption, and local irritation.

๐Ÿคฑ Lactation Safety

Use with caution; avoid application to breast area.

๐Ÿ’Š Overdose Management

Excessive topical use may cause systemic effects; discontinue use and treat symptomatically.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for blisderm ointment

View All

Alternative brands with exact same active ingredient (Halobetasol (0.05% w/w)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026

Found this to be a helpful product. Good results.

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