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d-veniz 100 tablet er

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Desvenlafaxine (100mg)

🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jul 5, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Jul 05, 2026

What is d-veniz 100 tablet er used for?

D-Veniz 50 Tablet ER (Desvenlafaxine) is used to treat NEURO CNS. It contains Desvenlafaxine (100mg), which Inhibits serotonin and norepinephrine reuptake (SNRI).. Always consult your doctor before use. Take as prescribed.

Generic Name: Desvenlafaxine
Manufacturer: Sun Pharmaceutical Industries Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 d-veniz 100 tablet er Uses & Benefits

Major depressive disorder (MDD).

Off-label uses: Anxiety disorders, Panic disorder, Social anxiety disorder, Neuropathic pain, Vasomotor symptoms of menopause

📋 Drug Information

Generic Name(s)	Desvenlafaxine
Brand Name	D-Veniz 50 Tablet ER
Manufacturer	Sun Pharmaceutical Industries Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Serotonin-norepinephrine reuptake inhibitors (SNRIs)
Route of Administration	Oral (extended-release tablet).
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; food does not affect absorption.

DistributionDistributed throughout the body; volume of distribution approximately 3.4 L/kg.

Protein Binding30% bound to plasma proteins.

MetabolismPrimarily metabolized by conjugation (UGT isoforms) and to a lesser extent by CYP3A4.

Half-LifeApproximately 11 hours.

ExcretionApproximately 45% excreted unchanged in urine; 19% as glucuronide conjugate.

BioavailabilityApproximately 80%.

Onset of ActionMay take 1-2 weeks for therapeutic effect.

Peak Plasma TimeAbout 7.5 hours (extended-release formulation).

Duration of Action24 hours (once-daily dosing).

How It Works

Inhibits serotonin and norepinephrine reuptake (SNRI).

Mechanism Steps

1Desvenlafaxine binds to SERT and NET, inhibiting reuptake of serotonin and norepinephrine.

2Increased synaptic concentrations of serotonin and norepinephrine enhance neurotransmission.

3Downregulation of postsynaptic receptors over time contributes to antidepressant effect.

💡 How to Take d-veniz 100 tablet er

Follow your doctor's prescription exactly.

⚠️ Side Effects of d-veniz 100 tablet er

✅ Common Side Effects

Nausea
Vomiting
Anxiety
Increased sweating
Insomnia
Constipation
Decreased appetite
Sexual dysfunction
Dizziness
Somnolence

🚨 Serious Side Effects

Serotonin syndrome
Suicidal thoughts or behaviors
Increased blood pressure
Angle-closure glaucoma
Seizures
Hyponatremia

⚠️ Rare Side Effects

Allergic reactions
Stevens-Johnson syndrome
Pancreatitis
Hepatitis
Rhabdomyolysis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Increased risk of serotonin syndrome
Linezolid	Major	Increased risk of serotonin syndrome
Methylene blue	Major	Increased risk of serotonin syndrome
SSRIs	Moderate	Additive serotonergic effects, risk of serotonin syndrome
SNRIs	Moderate	Additive serotonergic effects, risk of serotonin syndrome
Triptans	Moderate	Additive serotonergic effects, risk of serotonin syndrome
Lithium	Moderate	Increased risk of serotonin syndrome
Tramadol	Moderate	Increased risk of serotonin syndrome
St. John's Wort	Moderate	Increased risk of serotonin syndrome
Warfarin	Moderate	Increased bleeding risk
NSAIDs	Moderate	Increased bleeding risk
Aspirin	Moderate	Increased bleeding risk
Cimetidine	Minor	May increase desvenlafaxine levels
CYP3A4 inhibitors	Minor	May increase desvenlafaxine levels

🚨 Major Interactions

MAOIs
Linezolid
Methylene blue

⚡ Moderate Interactions

SSRIs
SNRIs
Triptans
Lithium
Tramadol
St. John's Wort
Warfarin
NSAIDs
Aspirin

ℹ️ Minor Interactions

Cimetidine
CYP3A4 inhibitors

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

Avoid alcohol; may increase CNS depression and risk of adverse effects.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to desvenlafaxine or any excipients; concomitant use with MAOIs or within 14 days of MAOI discontinuation.

📊 Monitoring Parameters

Blood pressure, heart rate, signs of serotonin syndrome, suicidal ideation, mood changes.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

Symptomatic and supportive care; monitor ECG, vital signs; consider activated charcoal if recent ingestion.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 05, 2026

🔗 View Profile

🔄 Substitutes for d-veniz 100 tablet er

View All

Alternative brands with exact same active ingredient (Desvenlafaxine (100mg)):

Medical Note: Always consult your doctor before switching medications.

😊 Was this information helpful?

📌 Quick Facts

Storage	Store at 20-25°C (68-77°F); protect from moisture.
Route	Oral (extended-release tablet).
Pregnancy	Category A
Breastfeeding	Excreted in breast milk; caution advised.
Alcohol	Avoid alcohol; may increase CNS depression and risk of adverse effects.
Onset of Action	May take 1-2 weeks for therapeutic effect.
Half-Life	Approximately 11 hours.
Prescription	✅ Required

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