cynacin 500mg tablet - Griseofulvin (500mg) medicine

cynacin 500mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Synmedic Laboratories ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is cynacin 500mg tablet used for?

Cytofulvin 500mg Tablet (Griseofulvin) is used to treat ANTI INFECTIVES. It contains Griseofulvin (500mg), which Inhibits fungal cell mitosis by disrupting microtubule function.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Griseofulvin
  • Manufacturer: Synmedic Laboratories
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š cynacin 500mg tablet Uses & Benefits

Dermatophyte infections of skin, hair, and nails (tinea capitis, tinea corporis, tinea pedis, tinea unguium)

Off-label uses: Tinea versicolor (limited evidence)

๐Ÿ“‹ Drug Information

Generic Name(s)Griseofulvin
Brand NameCytofulvin 500mg Tablet
ManufacturerSynmedic Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntifungal Others
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed from the gastrointestinal tract; absorption enhanced by fatty meal.
DistributionDistributed to skin, hair, nails, liver, fat, and skeletal muscles.
Protein BindingApproximately 97% bound to plasma proteins.
MetabolismHepatic metabolism via demethylation and glucuronide conjugation.
Half-Life9-24 hours
ExcretionExcreted in urine (as metabolites) and feces (as unchanged drug).
BioavailabilityVariable; enhanced by high-fat meal.
Onset of ActionSeveral days to weeks for clinical effect.
Peak Plasma Time4-8 hours
Duration of ActionLong; persists in skin and nails for weeks after discontinuation.

How It Works

Inhibits fungal cell mitosis by disrupting microtubule function.

Mechanism Steps

1Griseofulvin binds to fungal tubulin, inhibiting microtubule assembly.
2Disrupts mitotic spindle formation, arresting fungal cell division at metaphase.
3Interferes with fungal cell wall synthesis and nucleic acid synthesis.

๐Ÿ’ก How to Take cynacin 500mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cynacin 500mg tablet

โœ… Common Side Effects

  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Skin rash
  • Urticaria

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Angioedema
  • Leukopenia
  • Granulocytopenia

โš ๏ธ Rare Side Effects

  • Peripheral neuropathy
  • Confusion
  • Fatigue
  • Oral thrush
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Decreased anticoagulant effect
Barbiturates Major Decreased griseofulvin levels
Oral contraceptives Major Reduced contraceptive efficacy
Cyclosporine Major Decreased cyclosporine levels
Alcohol Moderate Increased hepatotoxicity risk
Phenytoin Moderate Decreased phenytoin levels
Theophylline Moderate Decreased theophylline levels
Antacids Minor Decreased griseofulvin absorption
Cimetidine Minor Increased griseofulvin levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Barbiturates
  • Oral contraceptives
  • Cyclosporine

โšก Moderate Interactions

  • Alcohol
  • Phenytoin
  • Theophylline

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

High-fat meals increase absorption

๐Ÿท Alcohol Interaction

May increase risk of hepatotoxicity; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Pregnancy, Lactation, Severe liver disease, Porphyria, Hypersensitivity to griseofulvin

๐Ÿ“Š Monitoring Parameters

Liver function tests, Renal function, Complete blood count, Signs of hypersensitivity

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk.

๐Ÿ’Š Overdose Management

Supportive care; induce vomiting or gastric lavage if recent ingestion.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cynacin 500mg tablet

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Alternative brands with exact same active ingredient (Griseofulvin (500mg)):

Medical Note: Always consult your doctor before switching medications.

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