cynacin 500mg tablet - Griseofulvin (500mg) medicine

Cytofulvin 500mg Tablet: Complete Medicine Guide

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🏭 Synmedic Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for dermatophyte infections
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, or throat, or difficulty breathing
  • Severe skin rash, blistering, or peeling
  • Yellowing of the skin or eyes, dark urine, or severe abdominal pain
  • Unusual bruising or bleeding
  • Persistent numbness, tingling, or weakness in the hands or feet
  • Severe or persistent headache with visual changes
  • High fever with sore throat or other signs of infection

If experiencing severe symptoms, call emergency services immediately.

What is cynacin 500mg tablet used for?

This medicine contains Griseofulvin 500mg, an antifungal used to treat fungal infections of the skin, hair, and nails. It works by stopping fungal growth and is taken orally with a fatty meal for better absorption.

  • Generic Name: Griseofulvin
  • Manufacturer: Synmedic Laboratories
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cynacin 500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ग्रिसियोफुल्विन 500mg युक्त एक एंटीफंगल टैबलेट है, जिसका उपयोग त्वचा, बालों और नाखूनों के फंगल संक्रमण के इलाज के लिए किया जाता है। यह दवा दाद, खाज-खुजली, एथलीट फुट और नाखून के फंगस जैसी समस्याओं में प्रभावी है। यह फंगस के विकास को रोककर संक्रमण को ठीक करने में मदद करती है। इसे भोजन के साथ लेना चाहिए ताकि यह शरीर में अच्छी तरह अवशोषित हो सके।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, जी मिचलाना, उल्टी, दस्त, पेट में असहजता और थकान शामिल हैं। कुछ लोगों को चक्कर आना, नींद न आना या स्वाद में बदलाव भी महसूस हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, पीलिया या हाथ-पैर में झुनझुनी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। लक्षण ठीक होने पर भी कोर्स पूरा करें, वरना संक्रमण दोबारा हो सकता है। इसे भोजन के साथ लें, खासकर वसायुक्त भोजन के साथ, ताकि यह अच्छी तरह अवशोषित हो। इस दवा के सेवन के दौरान शराब न पिएं। धूप में बाहर निकलते समय सनस्क्रीन और सुरक्षात्मक कपड़े पहनें। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। चक्कर आने पर वाहन न चलाएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 cynacin 500mg tablet Uses & Benefits

  • [{"condition":"Tinea capitis (scalp ringworm)","description":"This medicine is effective in treating fungal infections of the scalp, especially in children.
  • It helps clear the infection and prevents spread to others.","evidence":"Well-established"},{"condition":"Tinea corporis (body ringworm)","description":"Used for widespread or stubborn ringworm infections of the body that have not responded to topical antifungals.","evidence":"Well-established"},{"condition":"Tinea pedis (athlete's foot)","description":"Prescribed for severe or recurrent athlete's foot when topical treatments are insufficient.","evidence":"Well-established"},{"condition":"Tinea unguium (nail fungus)","description":"Used for fungal infections of the fingernails and toenails, often requiring several months of treatment.","evidence":"Well-established"},{"condition":"Tinea barbae (beard area fungal infection)","description":"Treats fungal infections affecting the beard and moustache area, which can be difficult to clear with creams alone.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Onychomycosis in immunocompromised patients","description":"Sometimes used off-label for nail fungus in patients with weakened immune systems, but close monitoring is required.","evidence":"Limited"}]

Primary treatment for: Dermatophyte fungal infections

Also treats: Tinea capitis, Tinea corporis, Tinea pedis, Tinea unguium, Tinea barbae

📋 Drug Information

Generic Name(s)Griseofulvin
Brand NameCytofulvin 500mg Tablet
ManufacturerSynmedic Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassAntifungal Others
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a fatty meal to enhance absorption.
2
Complete the full course as prescribed, even if symptoms improve.
3
Avoid alcohol while taking this medicine to reduce liver risk.
4
Use sunscreen and protective clothing when outdoors due to photosensitivity.
5
Inform your doctor if you are taking oral contraceptives, as this medicine may reduce their effectiveness.
6
Report any unusual bruising, bleeding, or signs of infection to your doctor promptly.
7
Keep follow-up appointments for monitoring of liver function and blood counts.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Ring-shaped rash with itching
This medicine is commonly prescribed for this.
Likely Use
✅
Scaly scalp with hair loss
This medicine is used for scalp fungal infections.
Likely Use
✅
Thick, discoloured nails
This medicine is used for nail fungus.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Cough
This medicine is not used for respiratory infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is absorbed from the gastrointestinal tract, and absorption is improved when taken with a fatty meal. Peak blood levels are usually reached within 4 to 8 hours after oral administration.
DistributionThis medicine is widely distributed throughout the body, including skin, hair, nails, and adipose tissue. It tends to accumulate in keratin-rich tissues, which is where it exerts its antifungal effect.
Protein BindingApproximately 80% of this medicine is bound to plasma proteins.
MetabolismThis medicine is metabolised in the liver, primarily by the cytochrome P450 enzyme system. The main metabolite is 6-desmethylgriseofulvin, which is inactive.
Half-LifeThe elimination half-life of this medicine is approximately 9 to 24 hours, but it may be longer in patients with liver impairment.
ExcretionThis medicine and its metabolites are excreted mainly through the urine, with a small amount eliminated in faeces and sweat.
BioavailabilityThe bioavailability of this medicine varies depending on the formulation and food intake. Taking it with a fatty meal significantly enhances absorption.
Onset of ActionImprovement in symptoms may be noticed within a few days to weeks, depending on the type and severity of the infection. However, complete cure may take several weeks to months.
Peak Plasma TimePeak plasma concentration is reached approximately 4 to 8 hours after oral administration.
Duration of ActionThe antifungal effect persists as long as therapeutic levels are maintained in the body. After stopping treatment, the medicine remains in keratinous tissues for several weeks, providing ongoing protection.

How It Works

This medicine works by binding to fungal tubulin, a protein that is essential for the formation of microtubules. By interfering with microtubule function, it disrupts the structure and division of fungal cells, preventing the fungus from growing and multiplying. This ultimately leads to the death of the fungal cells and clearance of the infection.

Mechanism Steps

1
Binding to fungal tubulin: This medicine binds to tubulin proteins within fungal cells, preventing them from polymerising into microtubules.
2
Disruption of microtubule function: Without functional microtubules, the fungal cell cannot maintain its shape, transport materials, or divide properly.
3
Inhibition of fungal growth: The disruption leads to arrested growth and eventual death of the fungal cells, allowing the body's immune system to clear the infection.

💡 How to Take cynacin 500mg tablet

Strength: Griseofulvin 500mg immediate-release tablet

1Take this medicine by mouth with a full glass of water.
2Take it with a meal that contains some fat to improve absorption.
3Swallow the tablet whole. Do not crush or chew.
4Take at the same time each day to maintain consistent blood levels.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 500mg taken once daily, but the exact dose and duration depend on the type and severity of the fungal infection. For skin infections, treatment may last 2 to 4 weeks; for nail infections, it may continue for several months. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be necessary based on liver and kidney function. Consult your doctor for personalized dosing.
Renal ImpairmentNo specific dose adjustment is provided in the available information. Use with caution in patients with kidney impairment. Consult your doctor for personalized dosing.
Hepatic ImpairmentThis medicine is metabolised in the liver. Dose reduction may be necessary in patients with liver impairment. Consult your doctor for personalized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 500mg for adults, but this may vary based on the indication and clinical judgment. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and enhances absorption.
Fatty meals
Take with a fatty meal
Improves absorption of this medicine.
Alcohol
Avoid
Increases risk of liver toxicity and side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cynacin 500mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. If persistent or severe, consult your doctor.
Nausea (Common (5-10%))
Take with food to reduce nausea. If it continues, speak to your doctor.
Vomiting (Common (5-10%))
Stay hydrated and inform your doctor if vomiting is severe or persistent.
Diarrhoea (Common (5-10%))
Drink plenty of fluids. If diarrhoea is severe or bloody, seek medical advice.
Stomach discomfort (Common (5-10%))
Take with meals to minimise stomach upset.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue interferes with daily activities, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, throat, difficulty breathing, or a severe rash.
Liver toxicity (Rare (<0.1%))
Report yellowing of the skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Blood disorders (e.g., leukopenia, neutropenia) (Rare (<0.1%))
Inform your doctor if you develop unusual bruising, bleeding, or signs of infection such as fever or sore throat.
Peripheral neuropathy (Rare (<0.1%))
Report numbness, tingling, or weakness in the hands or feet to your doctor.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek emergency care if you develop a painful rash, blistering, or peeling skin.

⚠️ Rare Side Effects

Photosensitivity
Use sunscreen and protective clothing when outdoors. Inform your doctor if you notice skin reactions.
Taste disturbance
Usually temporary. If it persists, consult your doctor.
Dizziness
Avoid driving or operating machinery until you know how this medicine affects you.
Insomnia
Practice good sleep hygiene. If insomnia persists, talk to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Oral contraceptives Major
Barbiturates Major
Alcohol Moderate
Cimetidine Moderate
Rifampicin Moderate
Aspirin Minor
Paracetamol Minor

🚨 Major Interactions

  • Warfarin
  • Oral contraceptives
  • Barbiturates (e.g., phenobarbital)

⚡ Moderate Interactions

  • Alcohol
  • Cimetidine
  • Rifampicin

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of liver damage and may worsen side effects such as dizziness, drowsiness, and nausea.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to griseofulvin or any component of this medicine","Porphyria (a rare blood disorder)","Severe liver disease","Pregnancy (unless clearly needed)","Breastfeeding"]

⚠️ Warnings & Precautions

["This medicine may cause dizziness or drowsiness. Avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine to reduce the risk of liver toxicity.","This medicine can make your skin more sensitive to sunlight. Use sunscreen and protective clothing.","Inform your doctor if you have a history of liver disease, kidney disease, or blood disorders.","This medicine may reduce the effectiveness of oral contraceptives. Use an additional method of contraception.","Do not stop taking this medicine without consulting your doctor, even if symptoms improve.","Keep all follow-up appointments for monitoring of liver function and blood counts."]

🤱 Lactation Safety

This medicine passes into breast milk and may affect the breastfed infant. It is not recommended during breastfeeding. Consult your doctor to discuss alternative treatments or feeding options.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, headache, dizziness, and confusion. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it early, even if you feel better, because the fungal infection may return. Take each dose with a meal that contains some fat to improve absorption. Avoid alcohol while taking this medicine, as it may increase the risk of liver problems and side effects. This medicine can make your skin more sensitive to sunlight, so use sunscreen and protective clothing when outdoors. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as this medicine may not be suitable for you. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Keep all follow-up appointments so your doctor can monitor your response and check for any side effects.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and liver toxicity. Dose adjustment may be necessary based on liver and kidney function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Use effective contraception while taking this medicine and for at least one month after stopping.

🏥 Post-Surgery Considerations

Inform your surgeon and anaesthesiologist that you are taking this medicine before any surgery. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with medications used during dental work.

💚 Lifestyle Tips for Better Results

🏃
Keep the affected area clean and dry.
🥗
Avoid sharing personal items like towels, combs, and shoes.
😴
Wear breathable footwear to prevent athlete's foot.
💧
Maintain good hygiene to prevent spread of fungal infections.
🧘
Follow a balanced diet to support your immune system.
🌞
Get adequate sleep to help your body fight infections.

🏋️ Exercise Considerations

This medicine may cause dizziness or fatigue. Avoid strenuous exercise if you feel unwell. Consult your doctor before starting any new exercise routine.

🥗 Diet Recommendations

Include fatty foods like milk, eggs, or nuts with your dose to enhance absorption.
Stay well hydrated.
Avoid alcohol.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your usual activities, but take precautions if you feel unwell.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if symptoms improve. Stopping early may allow the infection to return. Your doctor will determine the appropriate duration of treatment based on your condition.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of liver toxicity, blood disorders, and peripheral neuropathy. Regular monitoring of liver function and blood counts is recommended. If you experience any unusual symptoms, consult your doctor. The duration of treatment should be as short as necessary to clear the infection.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Topical antifungals

Creams or ointments may be used for mild skin infections.

Evidence: Well-established
Other oral antifungals

Terbinafine or itraconazole may be alternatives for certain fungal infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about this medicine before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually to maintain consistent blood levels. Check customs regulations for carrying prescription medicines into your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with toenail fungus
He was prescribed this medicine for a stubborn toenail fungal infection. He took it with breakfast every day and noticed gradual improvement over several months. He experienced mild stomach upset initially, which resolved when he took it with a fuller meal. He completed the full course and the infection cleared.
💡 Lesson: Consistency with daily dosing and taking the medicine with food improves tolerability and effectiveness.
👤 A 28-year-old woman with scalp ringworm
She developed an itchy, scaly patch on her scalp that was diagnosed as tinea capitis. She was prescribed this medicine and advised to take it with a fatty meal. Within two weeks, the itching reduced and the rash began to fade. She completed the 6-week course and the infection did not return.
💡 Lesson: Taking this medicine exactly as prescribed and completing the course is essential to prevent recurrence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement may be noticed within a few days to weeks, but complete cure can take several weeks to months depending on the infection.

Q: Can I take this medicine with food?

A: Yes, take it with a fatty meal to improve absorption and reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor.

Q: Can I drink alcohol while taking this medicine?

A: Avoid alcohol as it may increase the risk of liver toxicity and side effects.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cynacin 500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of fungal infection.
    Fact: This medicine is only effective against dermatophyte fungi. It does not treat systemic fungal infections or those caused by other types of fungi.
  • Myth: You can stop taking this medicine once symptoms improve.
    Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent the infection from returning.
  • Myth: This medicine is safe to take during pregnancy.
    Fact: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Griseofulvin 500mg tablet

Brand Alternatives

  • Cytofulvin 500mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Griseofulvin","class":"Antifungal","route":"Oral","common_use":"Dermatophyte infections","notes":"Requires fatty meal for absorption"},{"medicine":"Terbinafine","class":"Antifungal","route":"Oral/Topical","common_use":"Dermatophyte infections","notes":"More effective for nail infections"},{"medicine":"Itraconazole","class":"Antifungal","route":"Oral","common_use":"Broad-spectrum antifungal","notes":"More drug interactions"}]

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