cuzoyl 5% gel

4.7 (18 reviews)

Benzoyl Peroxide (5% w/w)

🏭 Cubit Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is cuzoyl 5% gel used for?

Aczest Creamy Face Wash (Benzoyl Peroxide) is used to treat DERMA. It contains Benzoyl Peroxide (5% w/w), which Oxidizing agent that releases free oxygen radicals, which oxidize bacterial prot. Always consult your doctor before use. Take as prescribed.

Generic Name: Benzoyl Peroxide
Manufacturer: Cubit Healthcare
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cuzoyl 5% gel Uses & Benefits

Treatment of acne vulgaris (mild to moderate).

Off-label uses: Treatment of folliculitis, Treatment of rosacea (off-label)

📋 Drug Information

Generic Name(s)	Benzoyl Peroxide
Brand Name	Aczest Creamy Face Wash
Manufacturer	Cubit Healthcare
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	DERMA
Action Class	Keratoplastic and keratolytic agents
Route of Administration	Topical
Storage	Store at 20-25°C (68-77°F); protect from excessive heat and light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after topical application; less than 5% absorbed through skin.

DistributionNot extensively distributed; remains primarily in skin layers.

Protein BindingNot applicable due to minimal systemic absorption.

MetabolismMetabolized in skin to benzoic acid, then conjugated with glycine to form hippuric acid and excreted renally.

Half-LifeNot well defined; rapid cutaneous metabolism.

ExcretionRenal excretion as hippuric acid.

BioavailabilityMinimal systemic bioavailability (<5%).

Onset of ActionWithin 2-3 days of regular use.

Peak Plasma TimeNot applicable due to topical route.

Duration of ActionSustained antimicrobial effect for up to 48 hours after application.

How It Works

Oxidizing agent that releases free oxygen radicals, which oxidize bacterial proteins and inhibit bacterial growth; also has keratolytic and comedolytic effects.

Mechanism Steps

1Benzoyl peroxide penetrates the stratum corneum and enters pilosebaceous units.

2It decomposes to release free oxygen radicals.

3Free radicals oxidize bacterial proteins and lipids, disrupting cell membranes of Propionibacterium acnes.

💡 How to Take cuzoyl 5% gel

Follow your doctor's prescription exactly.

⚠️ Side Effects of cuzoyl 5% gel

✅ Common Side Effects

Skin irritation
Dryness
Peeling
Redness
Stinging or burning sensation

🚨 Serious Side Effects

Severe allergic reactions (rash, hives, itching, difficulty breathing)
Severe skin irritation or blistering

⚠️ Rare Side Effects

Contact dermatitis
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Tretinoin	Major	Increased skin irritation and possible inactivation of tretinoin if used concurrently.
Isotretinoin	Major	Increased risk of severe skin irritation and dryness.
Sunscreens containing aminobenzoic acid	Major	May cause temporary skin discoloration.
Clindamycin topical	Moderate	Possible additive irritation.
Erythromycin topical	Moderate	Possible additive irritation.
Other topical acne agents	Moderate	Increased skin dryness and peeling.
Cosmetics containing alcohol or astringents	Minor	Increased drying effect.

🚨 Major Interactions

Tretinoin
Isotretinoin
Sunscreens containing aminobenzoic acid

⚡ Moderate Interactions

Clindamycin topical
Erythromycin topical
Other topical acne agents

ℹ️ Minor Interactions

Cosmetics containing alcohol or astringents

🍽️ Food Interactions

None known.

🍷 Alcohol Interaction

May increase skin irritation and dryness.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to benzoyl peroxide or any component of the formulation.

📊 Monitoring Parameters

Monitor for skin irritation, redness, peeling, and improvement of acne lesions.

🤱 Lactation Safety

Safety not established; use with caution. Minimal systemic absorption suggests low risk.

💊 Overdose Management

Overdose unlikely due to topical use; if ingested, treat symptomatically and supportively.

⏰ Missed Dose

Apply as soon as remembered; if almost time for next dose, skip missed dose and resume regular schedule. Do not double up.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for cuzoyl 5% gel

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Alternative brands with exact same active ingredient (Benzoyl Peroxide (5% w/w)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026