creslip 40mg/10mg tablet - Uses, Price, Side Effects & Substitutes
What is creslip 40mg/10mg tablet used for?
Arbitel-AV Tablet (Telmisartan + Atorvastatin) is used to treat CARDIAC. It contains Telmisartan (40mg) + Atorvastatin (10mg), which Telmisartan blocks angiotensin II AT1 receptors, causing vasodilation and reduce. Always consult your doctor before use. Take as prescribed.
- Generic Name: Telmisartan + Atorvastatin
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ creslip 40mg/10mg tablet Uses & Benefits
Hypertension with dyslipidemia, cardiovascular risk reduction.
Off-label uses: Diabetic nephropathy, migraine prophylaxis (telmisartan), familial hypercholesterolemia (atorvastatin).
๐ Drug Information
| Generic Name(s) | Telmisartan + Atorvastatin |
| Brand Name | Arbitel-AV Tablet |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin II Receptor Blocker + HMG-CoA Reductase Inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Telmisartan blocks angiotensin II AT1 receptors, causing vasodilation and reduced aldosterone secretion. Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis.
Mechanism Steps
๐ก How to Take creslip 40mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of creslip 40mg/10mg tablet
โ Common Side Effects
- Headache
- Dizziness
- Diarrhea
- Muscle pain
- Upper respiratory infection
๐จ Serious Side Effects
- Angioedema
- Rhabdomyolysis
- Hepatotoxicity
- Renal impairment
- Hypotension
โ ๏ธ Rare Side Effects
- Pancreatitis
- Interstitial lung disease
- Stevens-Johnson syndrome
- Myasthenia gravis exacerbation
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | Increased INR and bleeding risk |
| Ketoconazole | Major | Increased atorvastatin levels and myopathy risk |
| Cyclosporine | Major | Increased atorvastatin levels and myopathy risk |
| Gemfibrozil | Major | Increased risk of myopathy/rhabdomyolysis |
| Rifampin | Major | Decreased atorvastatin efficacy |
| Digoxin | Major | Increased digoxin levels |
| Antacids | Moderate | Reduced telmisartan absorption |
| Colchicine | Moderate | Increased risk of myopathy |
| Fibrates | Moderate | Increased risk of myopathy |
| Niacin | Moderate | Increased risk of myopathy |
| Grapefruit juice | Minor | Increased atorvastatin levels |
| Oral contraceptives | Minor | Increased contraceptive levels |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole)
- Cyclosporine
- Gemfibrozil
- Rifampin
- Digoxin
โก Moderate Interactions
- Warfarin
- Antacids
- Colchicine
- Fibrates
- Niacin
โน๏ธ Minor Interactions
- Grapefruit juice
- Oral contraceptives
- Digoxin
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase atorvastatin levels; avoid high-fat meals with telmisartan.
๐ท Alcohol Interaction
May increase risk of liver damage and hypotension.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Pregnancy, lactation, hypersensitivity, active liver disease, severe renal impairment, concomitant use with strong CYP3A4 inhibitors.
๐ Monitoring Parameters
Blood pressure, lipid profile, liver enzymes, renal function, muscle symptoms.
๐คฑ Lactation Safety
Contraindicated; avoid breastfeeding.
๐ Overdose Management
Symptomatic and supportive; monitor BP, ECG, liver function; consider gastric lavage.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double.