Aximol-M Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is cozynim p oral suspension used for?
This medicine is a combination of mefenamic acid and paracetamol used for short-term relief of mild to moderate pain and fever. It works by reducing inflammation and pain signals in the body. Take it with food and do not exceed the recommended dose.
- Generic Name: Mefenamic Acid + Paracetamol
- Manufacturer: PRM Life Sciences Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cozynim p oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा मेफेनामिक एसिड और पैरासिटामोल का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द और बुखार से राहत के लिए किया जाता है। यह दांत दर्द, सिर दर्द, मांसपेशियों में दर्द, पीरियड्स के दर्द और बुखार में प्रभावी है। इसे भोजन के साथ लें और डॉक्टर की सलाह के बिना लंबे समय तक न लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, कब्ज, सिर दर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट के अल्सर, गैस्ट्रोइंटेस्टाइनल रक्तस्राव, गुर्दे की समस्या, यकृत की क्षति और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकते हैं। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, आंखों या त्वचा का पीलापन, पेशाब में कमी, चेहरे या गले में सूजन या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें और निर्देशित समय से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। इस दवा के साथ शराब न लें क्योंकि इससे पेट में रक्तस्राव और यकृत की समस्या का खतरा बढ़ सकता है। पैरासिटामोल या अन्य NSAIDs वाली दवाओं को डॉक्टर की सलाह के बिना न लें। यदि आपको गुर्दे या यकृत की बीमारी, हृदय की समस्या, उच्च रक्तचाप या अस्थमा है तो डॉक्टर को बताएं। गर्भवती महिलाओं को विशेष रूप से तीसरी तिमाही में इस दवा से बचना चाहिए। स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 cozynim p oral suspension Uses & Benefits
[{"condition":"Mild to moderate pain","description":"Relieves pain from various causes such as headache, toothache, muscle ache, and back pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever due to its paracetamol content.","evidence":"Well-established"},{"condition":"Menstrual cramps (dysmenorrhea)","description":"Mefenamic acid effectively reduces menstrual pain and inflammation.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and post-dental procedure pain.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Eases pain from sprains, strains, and minor injuries.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks.","evidence":"Limited"},{"condition":"Post-operative pain","description":"May be used off-label for short-term post-operative pain management.","evidence":"Limited"}]
Primary treatment for: Pain and fever
Also treats: Menstrual cramps, Dental pain, Musculoskeletal pain, Headache
📋 Drug Information
| Generic Name(s) | Mefenamic Acid + Paracetamol |
| Brand Name | Abmef-DS Oral Suspension |
| Manufacturer | PRM Life Sciences Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Mefenamic acid is a non-steroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesic and antipyretic effects without significant anti-inflammatory action. Together, they provide enhanced pain relief and fever reduction.
Mechanism Steps
💡 How to Take cozynim p oral suspension
Strength: Each 5 ml of suspension contains Mefenamic Acid 50 mg and Paracetamol 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this suspension is 5 to 10 ml (containing 50-100 mg mefenamic acid and 125-250 mg paracetamol) taken orally every 6 to 8 hours as needed for pain and fever. Do not exceed 30 ml in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take with food or milk to reduce stomach upset. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing based on the child's age and weight. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed 30 ml of this suspension in adults. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cozynim p oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Major | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Antacids | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- Corticosteroids
- Methotrexate
- ACE inhibitors and ARBs
⚡ Moderate Interactions
- Diuretics
- Lithium
- SSRIs
- Antacids
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, stomach ulcers, and liver damage, especially when combined with paracetamol and mefenamic acid.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active stomach ulcer or history of recurrent ulcers","Severe kidney disease","Severe liver disease","Asthma triggered by aspirin or other NSAIDs","Allergy to mefenamic acid, paracetamol, or any component","Third trimester of pregnancy","Children below 12 years (unless specifically prescribed)","Coronary artery bypass graft surgery"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose.","Consult doctor before use if you have kidney or liver disease.","Use with caution in elderly patients.","May cause drowsiness; avoid driving if affected.","Do not use for more than 7 days without medical advice.","Inform your doctor if you are pregnant or breastfeeding."]
🤱 Lactation Safety
Mefenamic acid and paracetamol are excreted in breast milk in small amounts. Consult your doctor before use during breastfeeding. Short-term use is generally considered acceptable but medical advice is recommended.
💊 Overdose Management
Overdose can cause severe liver damage, kidney failure, and gastrointestinal bleeding. Seek immediate medical attention. Treatment includes activated charcoal, supportive care, and acetylcysteine for paracetamol toxicity. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver problems. Do not take other medicines containing paracetamol or other NSAIDs without consulting your doctor. If you have kidney or liver disease, heart failure, high blood pressure, or asthma, inform your doctor before using this medicine. Pregnant women, especially in the third trimester, should avoid this medicine unless specifically advised by a doctor. Breastfeeding mothers should consult their doctor before use. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning pregnancy. Avoid use, especially in the third trimester, as it may harm the fetus.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, as it may increase bleeding risk and interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how it affects you. It may affect your ability to concentrate.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects, if symptoms worsen, or if you need to take it for more than 7 days. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of stomach ulcers, gastrointestinal bleeding, kidney problems, and liver damage. Regular monitoring of kidney and liver function may be required. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help relieve localized pain and inflammation.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medicines. Keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it.
A: It is best taken with food or milk to reduce stomach upset.
A: Pediatric dosing is not established from available information. Consult a pediatrician.
A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for cozynim p oral suspension
View AllAlternative brands with exact same active ingredient:
-
mefago plus syrupFigomed Health Care Pvt Ltd ₹25.78 8.9% CHEAPER
-
mefojem p oral suspensionVibcare Pharma Pvt Ltd ₹26.25 7.2% CHEAPER
-
dolomec mf syrupMcW Healthcare ₹26.58 6.1% CHEAPER
-
pyribus-m suspensionGlobus Remedies Ltd ₹26.58 6.1% CHEAPER
-
mefastal p syrupStallion Laboratories Pvt Ltd ₹27.00 4.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of pain.
Fact: This medicine is for short-term relief of mild to moderate pain and fever. It is not a cure for underlying conditions. - Myth: It is safe to take this medicine for a long time.
Fact: Long-term use can cause serious side effects like stomach ulcers, kidney problems, and liver damage. Use only as prescribed. - Myth: You can take this medicine on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach upset.
🔄 Alternative Options
Generic Alternatives
- Mefenamic acid + Paracetamol suspension