Auxib P 60mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash or blistering
If experiencing severe symptoms, call emergency services immediately.
What is coxstar-p tablet used for?
This medicine is a combination of Etoricoxib 60 mg and Paracetamol 325 mg used for short-term relief of acute musculoskeletal pain, osteoarthritis, and dental pain. It works by reducing inflammation and pain through different mechanisms. Take it exactly as prescribed, usually once daily with food, and avoid alcohol. Do not use for more than 7 days without medical advice.
- Generic Name: Etoricoxib + Paracetamol
- Manufacturer: Metamorf Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coxstar-p tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरिकॉक्सिब 60 मिलीग्राम और पैरासिटामोल 325 मिलीग्राम का संयोजन है। इसका उपयोग मांसपेशियों और जोड़ों के दर्द, सूजन, ऑस्टियोआर्थराइटिस, रुमेटॉइड आर्थराइटिस, दांत दर्द और गाउट के दर्द से राहत के लिए किया जाता है। यह दर्द और सूजन को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, अपच, पेट दर्द, सिरदर्द, चक्कर आना और रक्तचाप में वृद्धि शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति, हृदयाघात और स्ट्रोक शामिल हो सकते हैं। यदि आपको काला मल, उल्टी में खून, त्वचा या आंखों का पीलापन, या पेशाब में कमी दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। इस दवा के साथ शराब का सेवन न करें। यदि आपको पेट के अल्सर, गुर्दे, यकृत या हृदय की बीमारी है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान बिना डॉक्टर की सलाह के न लें। बच्चों को 16 वर्ष से कम उम्र में न दें। दवा को ठंडी और सूखी जगह पर रखें।
💊 coxstar-p tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Osteoarthritis","description":"Reduces joint pain and stiffness, improving physical function in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Helps manage pain and inflammation in rheumatoid arthritis as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Post-operative dental pain","description":"Provides short-term relief of pain following dental surgery or extraction.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"Used for short-term relief of pain and inflammation during acute gout attacks.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine relief, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but not a first-line option.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain
Also treats: Osteoarthritis, Rheumatoid arthritis, Post-operative dental pain, Acute gouty arthritis
📋 Drug Information
| Generic Name(s) | Etoricoxib + Paracetamol |
| Brand Name | Auxib P 60mg/325mg Tablet |
| Manufacturer | Metamorf Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID (COX-2 inhibitor) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight, moisture, and heat. Do not refrigerate unless specified. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Etoricoxib selectively inhibits cyclooxygenase-2 (COX-2), an enzyme induced during inflammation that converts arachidonic acid into prostaglandins, which are mediators of pain, fever, and swelling. By blocking COX-2, etoricoxib reduces prostaglandin production at the site of inflammation, leading to analgesic, anti-inflammatory, and antipyretic effects. Paracetamol, on the other hand, acts primarily in the central nervous system by inhibiting prostaglandin synthesis and modulating pain perception, though its exact mechanism is not fully understood. Together, they provide enhanced pain relief through different pathways.
Mechanism Steps
💡 How to Take coxstar-p tablet
Strength: Tablet containing Etoricoxib 60 mg and Paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily, preferably with food. The dose may be adjusted by your doctor based on the severity of pain and your response to treatment. For acute pain, it is generally used for the shortest duration possible. For chronic conditions like osteoarthritis, your doctor may prescribe it for longer periods with regular monitoring. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding, kidney problems, and cardiovascular events. Use with caution and monitor closely. Dose adjustment may be necessary based on kidney and liver function. Consult your doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with kidney disease. For patients with severe kidney impairment (creatinine clearance less than 30 mL/min), etoricoxib is not recommended. Dose adjustment may be needed for mild to moderate impairment. Consult your doctor for personalized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. For patients with severe liver impairment (Child-Pugh score 10 or higher), etoricoxib is not recommended. Dose adjustment may be needed for mild to moderate impairment. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is one tablet (Etoricoxib 60 mg + Paracetamol 325 mg) per day. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coxstar-p tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Rifampicin | Moderate | |
| Antacids | Minor | |
| Aspirin | Minor |
🚨 Major Interactions
- Warfarin
- ACE inhibitors
- Diuretics
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Rifampicin
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding, ulcers, and liver damage, especially when combined with paracetamol and etoricoxib. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe liver disease","Severe kidney disease","Allergy to etoricoxib, paracetamol, or any NSAID","Pregnancy (third trimester)","Children under 16 years of age","Inflammatory bowel disease","Cerebrovascular disease"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients.","Monitor blood pressure regularly.","Inform your doctor if you have a history of heart, kidney, or liver disease.","Do not use if you are pregnant or breastfeeding without medical advice.","May cause dizziness; avoid driving if affected.","Stop and seek medical help if you experience signs of allergic reaction.","Do not take other NSAIDs or paracetamol-containing products concurrently."]
🤱 Lactation Safety
Not established from the available information. Etoricoxib may pass into breast milk, and its effects on the nursing infant are unknown. Paracetamol is considered safe during breastfeeding when used as directed. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and may also lead to kidney failure, gastrointestinal bleeding, and cardiovascular events. Symptoms of paracetamol overdose may not appear immediately and can include nausea, vomiting, abdominal pain, and confusion. If you suspect an overdose, seek emergency medical help immediately. Treatment may include activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care. Do not wait for symptoms to appear.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take it with food or a glass of water to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver problems. Do not take other pain relievers or NSAIDs without consulting your doctor. If you have a history of stomach ulcers, kidney disease, liver disease, heart disease, or high blood pressure, inform your doctor before taking this medicine. Do not use this medicine if you are pregnant, especially in the third trimester, or breastfeeding without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat. If you experience any unusual symptoms like black stools, vomiting blood, severe abdominal pain, yellowing of eyes or skin, or decreased urination, seek immediate medical help.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events when taking this medicine. Use with caution and monitor closely. Dose adjustment may be necessary based on kidney and liver function. Avoid long-term use unless clearly necessary. Regular follow-up with your doctor is important.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like etoricoxib may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Paracetamol is considered safer but should be used at the lowest effective dose for the shortest duration. Discuss alternative pain management options with your doctor.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain relief, but it should be used with caution after surgery due to the risk of bleeding and kidney problems. Inform your surgeon and anesthesiologist about all medications you are taking. Do not take this medicine without your doctor's approval after surgery, especially if you are on blood thinners.
🦷 Dental Procedures
This medicine can be used for pain relief after dental procedures such as tooth extraction. However, inform your dentist about all medications you are taking, especially if you are on anticoagulants. It may increase the risk of bleeding during dental surgery. Your dentist may recommend stopping it before certain procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or fatigue. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have joint pain, consult a physiotherapist for safe exercises. Do not overexert yourself, as this may worsen your condition.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Most people can continue their daily activities, but if you experience side effects, adjust your schedule accordingly. Inform your employer if you need accommodations.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience serious side effects such as black stools, vomiting blood, severe abdominal pain, yellowing of skin or eyes, decreased urine output, or signs of an allergic reaction. Do not stop taking this medicine abruptly if you have been on long-term therapy without consulting your doctor, as this may cause rebound symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver damage, and cardiovascular events such as heart attack and stroke. Regular monitoring of blood pressure, kidney function, liver function, and complete blood count is recommended. It is important to use the lowest effective dose for the shortest duration possible. If long-term therapy is needed, your doctor may consider alternative treatments or add protective medications like proton pump inhibitors.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay provide localized pain relief with fewer systemic side effects.
Evidence: Well-establishedMay help reduce pain in some patients with chronic musculoskeletal conditions.
Evidence: ModerateCan help alleviate pain and inflammation in acute injuries.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking. It is generally safe to receive vaccines while on this medicine, but consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking your dose at the same time each day as prescribed. For air travel, keep it in your carry-on luggage. Check customs regulations for restricted medicines in your destination country. Always carry enough supply for your trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it. Maximum pain relief may take a few days of regular use.
A: It is best to take this medicine with food or a glass of water to reduce the risk of stomach upset. Taking it on an empty stomach may increase the chance of indigestion.
A: Do not take other NSAIDs or paracetamol-containing products without consulting your doctor, as this can increase the risk of side effects.
A: If you are taking it for acute pain, you may stop when the pain resolves. For chronic conditions, consult your doctor before stopping.
A: Mild side effects like nausea or headache usually go away. If you experience serious side effects like black stools, severe abdominal pain, or allergic reactions, seek immediate medical help.
🤔 Common Patient Concerns
🔄 Substitutes for coxstar-p tablet
View AllAlternative brands with exact same active ingredient:
-
davacox p 60mg/325mg tabletDavaindia Generic Pharmacy ₹28.00 46.9% CHEAPER
-
etopax plus 60mg/325mg tabletRadico Remedies ₹51.56 2.3% CHEAPER
-
eutor-p tabletNovogen Captab ₹52.50 0.5% CHEAPER
-
velcox-p tabletVintek Pharmaceuticals ₹52.69 0.1% CHEAPER
-
Torik P 60mg/325mg TabletMedok Life Sciences Pvt Ltd ₹56.28 6.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is completely safe and can be taken without a prescription.
Fact: This medicine is a prescription drug and can cause serious side effects. It should only be taken under medical supervision. - Myth: Taking this medicine with alcohol is safe.
Fact: Alcohol increases the risk of stomach bleeding and liver damage when taken with this medicine. Avoid alcohol. - Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for inflammatory and musculoskeletal pain. It is not appropriate for all types of pain and should be used as prescribed. - Myth: If I miss a dose, I should double the next dose.
Fact: Never double the dose. Follow the missed dose instructions or consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Etoricoxib 60 mg + Paracetamol 325 mg tablet (generic)
Brand Alternatives
- Auxib P 60mg/325mg Tablet