Alkof Cofgel Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is coughrest tablet used for?
This medicine is a combination of guaifenesin and bromhexine used to treat productive cough with thick mucus. It works by thinning mucus and making it easier to cough out. It is not for dry cough.
- Generic Name: Guaifenesin + Bromhexine
- Manufacturer: Mankind Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coughrest tablet के बारे में (Hindi Summary)
उपयोग: यह दवा गुआइफेनेसिन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी और छाती में जकड़न के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है। यह सूखी खांसी के लिए नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, सिरदर्द और चक्कर आना शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। यदि आपको गंभीर एलर्जी, सांस लेने में कठिनाई, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुद से मात्रा न बढ़ाएं। पर्याप्त पानी पिएं। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। 7 दिनों से अधिक इसका उपयोग न करें। बच्चों की पहुंच से दूर रखें।
💊 coughrest tablet Uses & Benefits
[{"condition":"Productive cough with thick mucus","description":"Helps thin and loosen mucus in the airways, making it easier to cough out.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used to relieve chest congestion and facilitate mucus clearance in acute bronchitis.","evidence":"Moderate"},{"condition":"Chronic obstructive pulmonary disease (COPD) exacerbations","description":"May help in clearing secretions during exacerbations, but not a primary treatment.","evidence":"Limited"},{"condition":"Upper respiratory tract infections with mucus","description":"Provides symptomatic relief of chest congestion associated with common colds and flu.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Sinusitis with thick secretions","description":"Sometimes used off-label to help thin sinus secretions and relieve congestion.","evidence":"Limited"},{"condition":"Post-surgical atelectasis prevention","description":"Occasionally used to help clear secretions in post-operative patients, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Productive cough with thick mucus
Also treats: Acute bronchitis, Chronic obstructive pulmonary disease (COPD) exacerbations, Upper respiratory tract infections
📋 Drug Information
| Generic Name(s) | Guaifenesin + Bromhexine |
| Brand Name | Alkof Cofgel Tablet |
| Manufacturer | Mankind Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Expectorant and Mucolytic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions by stimulating gastric reflexes and directly acting on the respiratory tract. Bromhexine is a mucolytic that breaks down acidic mucopolysaccharide fibers in mucus, reducing its viscosity and making it easier to expel. Together, they enhance mucus clearance from the airways.
Mechanism Steps
💡 How to Take coughrest tablet
Strength: Not established from the available information.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and follow your doctor's advice. Dose adjustment may be necessary based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be required. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be required. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose should not exceed the recommended dose as prescribed by your doctor. Do not exceed 3 tablets in 24 hours unless directed by a physician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coughrest tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Codeine | Major | |
| Dextromethorphan | Major | |
| MAOIs | Major | |
| Atropine | Moderate | |
| Amoxicillin | Moderate | |
| Tetracycline | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Cough suppressants (e.g., codeine, dextromethorphan)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine)
- Antibiotics (e.g., amoxicillin, tetracycline)
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and gastrointestinal upset. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to guaifenesin, bromhexine, or any component of the formulation.","Children under 2 years of age.","Peptic ulcer disease.","Severe liver disease.","Severe kidney disease.","Concurrent use with MAOIs."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Do not use for dry cough or for more than 7 days without medical advice.","Use with caution in patients with asthma.","Use with caution in patients with a history of peptic ulcer.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor before use if pregnant or breastfeeding.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether guaifenesin and bromhexine pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal discomfort. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Drink plenty of water while taking this medicine to help loosen mucus. Avoid taking this medicine with alcohol or other cough suppressants unless advised by your doctor. If you have a history of stomach ulcers, asthma, or liver or kidney disease, inform your doctor before taking this medicine. Do not use this medicine for a dry cough or for more than 7 days without medical advice. Keep this medicine out of reach of children. Store in a cool, dry place away from direct sunlight. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and gastrointestinal upset. Use with caution and follow your doctor's advice.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Safety in pregnancy is not established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, especially if you are taking other medications or have underlying conditions.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have a cough or fever. Light activity like walking may be okay if you feel up to it. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to work if you feel well.
🛑 When to Stop This Medicine
Stop taking this medicine if your cough persists for more than 7 days, or if you develop a fever, rash, or difficulty breathing. Consult your doctor before stopping if you are unsure.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to gastrointestinal upset and rarely liver enzyme elevation. Regular monitoring may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion.
Evidence: Well-establishedCan help clear nasal passages and reduce postnasal drip.
Evidence: ModerateSoothes the throat and may help with cough.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions reported. However, if you have a fever or acute illness, consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to notice loosening of mucus within 30 minutes to 1 hour, but full effect may take a few doses.
A: Do not take with cough suppressants as they may counteract the effect. Consult your doctor before combining.
A: Consult your doctor before use. Safety is not established.
A: Take it as soon as you remember, but if it's almost time for the next dose, skip it. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for coughrest tablet
View AllAlternative brands with exact same active ingredient:
-
cofcad dl tabletZydus Healthcare Limited ₹6.56 29% CHEAPER
-
mericof tabletWockhardt Ltd ₹6.68 27.7% CHEAPER
-
respi q tabletAlembic Pharmaceuticals Ltd ₹6.91 25.2% CHEAPER
-
cuffit q tabletSun Pharmaceutical Industries Ltd ₹7.47 19.2% CHEAPER
-
okas q tabletCipla Ltd ₹7.56 18.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: It is only effective for productive cough with thick mucus. It is not for dry cough. - Myth: It is safe to take for long periods.
Fact: It should not be used for more than 7 days without medical advice. - Myth: It can be taken with any other cough medicine.
Fact: It should not be taken with cough suppressants as they may counteract its effect.
🔄 Alternative Options
Generic Alternatives
- Guaifenesin + Bromhexine tablet (generic)
Brand Alternatives
- Alkof Cofgel Tablet