cosalic-k solution - Ketoconazole (2% w/v) + Coal Tar (2% w/v) medicine

cosalic-k solution

4.5 (15 reviews)
๐Ÿญ Salve Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is cosalic-k solution used for?

Biokera Plus Scalp Lotion (Ketoconazole + Coal Tar) is used to treat DERMA. It contains Ketoconazole (2% w/v) + Coal Tar (2% w/v), which Ketoconazole inhibits fungal ergosterol synthesis; coal tar reduces epidermal pr. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ketoconazole + Coal Tar
  • Manufacturer: Salve Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š cosalic-k solution Uses & Benefits

Seborrheic dermatitis, dandruff, psoriasis of scalp

Off-label uses: Tinea capitis, pityriasis versicolor

๐Ÿ“‹ Drug Information

Generic Name(s)Ketoconazole + Coal Tar
Brand NameBiokera Plus Scalp Lotion
ManufacturerSalve Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntifungal + Keratolytic
Route of AdministrationTopical (scalp lotion)
StorageStore at room temperature (20-25ยฐC); keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption; primarily local action on scalp
DistributionLimited to skin and scalp; negligible systemic distribution
Protein BindingNot applicable (topical)
MetabolismHepatic for absorbed fraction (ketoconazole); coal tar not metabolized
Half-LifeNot applicable (topical)
ExcretionRenal for absorbed ketoconazole; coal tar excreted via feces
BioavailabilityNegligible systemic bioavailability
Onset of ActionWithin 1-2 weeks of regular use
Peak Plasma TimeNot applicable (topical)
Duration of ActionLasts for several days after application

How It Works

Ketoconazole inhibits fungal ergosterol synthesis; coal tar reduces epidermal proliferation and scaling

Mechanism Steps

1Ketoconazole binds to fungal lanosterol 14-alpha-demethylase
2Inhibits conversion of lanosterol to ergosterol
3Disrupts fungal cell membrane integrity

๐Ÿ’ก How to Take cosalic-k solution

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cosalic-k solution

โœ… Common Side Effects

  • Local irritation
  • Dryness
  • Itching
  • Stinging

๐Ÿšจ Serious Side Effects

  • Allergic reaction
  • Skin atrophy
  • Hepatotoxicity (rare)

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Hair discoloration
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk (systemic absorption)
CYP3A4 substrates Major Increased levels of substrate (systemic absorption)

๐Ÿšจ Major Interactions

  • Warfarin
  • CYP3A4 substrates (systemic ketoconazole)

โšก Moderate Interactions

  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Topical medications

๐Ÿฝ๏ธ Food Interactions

None known

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component; open wounds or infected skin

๐Ÿ“Š Monitoring Parameters

Scalp condition, signs of irritation, liver function if prolonged use

๐Ÿคฑ Lactation Safety

Use with caution; avoid application to breast area

๐Ÿ’Š Overdose Management

Unlikely; if ingested, symptomatic treatment

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

โญ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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