coravas-fb tablet - Uses, Price, Side Effects & Substitutes
What is coravas-fb tablet used for?
Atorlip-F Tablet (Atorvastatin + Fenofibrate) is used to treat CARDIAC. It contains Atorvastatin (10mg) + Fenofibrate (160mg), which Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofib. Always consult your doctor before use. Take as prescribed.
- Generic Name: Atorvastatin + Fenofibrate
- Manufacturer: Corazon Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
π coravas-fb tablet Uses & Benefits
Primary hypercholesterolemia, mixed dyslipidemia, hypertriglyceridemia.
Off-label uses: Secondary prevention of cardiovascular events, non-alcoholic fatty liver disease.
π Drug Information
| Generic Name(s) | Atorvastatin + Fenofibrate |
| Brand Name | Atorlip-F Tablet |
| Manufacturer | Corazon Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Lipid-lowering agents (Statin + Fibrate) |
| Route of Administration | Oral |
| Storage | Store at 20-25Β°C, protect from light and moisture. |
| Shelf Life | As per manufacturer |
π¬ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis; Fenofibrate activates PPARΞ±, increasing lipolysis and VLDL clearance.
Mechanism Steps
π‘ How to Take coravas-fb tablet
Follow your doctor's prescription exactly.
β οΈ Side Effects of coravas-fb tablet
β Common Side Effects
- Myalgia
- Diarrhea
- Nasopharyngitis
- Headache
- Abdominal pain
π¨ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Pancreatitis
- Renal failure
- Angioedema
β οΈ Rare Side Effects
- Peripheral neuropathy
- Interstitial lung disease
- Tendon rupture
- Gynecomastia
Consult your doctor if you experience any unusual symptoms.
π¬ Drug Interactions
| β οΈ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Cyclosporine | Major | Increased risk of myopathy/rhabdomyolysis |
| Gemfibrozil | Major | Increased risk of myopathy |
| Macrolide antibiotics | Major | Increased atorvastatin levels |
| Azole antifungals | Major | Increased atorvastatin levels |
| HIV protease inhibitors | Major | Increased atorvastatin levels |
| Digoxin | Moderate | Increased digoxin levels |
| Oral contraceptives | Moderate | Increased contraceptive levels |
| Colchicine | Moderate | Increased risk of myopathy |
| Niacin | Moderate | Increased risk of myopathy |
| Antacids | Minor | Reduced atorvastatin absorption |
| Rifampin | Minor | Reduced atorvastatin levels |
| St. John's Wort | Minor | Reduced atorvastatin levels |
π¨ Major Interactions
- Warfarin
- Cyclosporine
- Gemfibrozil
- Macrolide antibiotics
- Azole antifungals
- HIV protease inhibitors
β‘ Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Fibrates (other)
- Niacin
βΉοΈ Minor Interactions
- Antacids
- Rifampin
- St. John's Wort
π½οΈ Food Interactions
Grapefruit juice increases atorvastatin levels; high-fat meal increases fenofibrate absorption.
π· Alcohol Interaction
May increase risk of hepatotoxicity; avoid excessive alcohol.
π‘οΈ Safety & Warnings
π« Contraindications
Active liver disease, unexplained LFT elevations, pregnancy, lactation, hypersensitivity, severe renal impairment.
π Monitoring Parameters
Lipid profile, LFTs, CPK, renal function, INR if on warfarin.
π€± Lactation Safety
Contraindicated; excreted in milk.
π Overdose Management
Supportive care; monitor liver and renal function; no specific antidote.
β° Missed Dose
Take as soon as remembered unless near next dose; skip if close.