convulex 500mg tablet er - Uses, Price, Side Effects & Substitutes
What is convulex 500mg tablet er used for?
Alporate (Valproic Acid) is used to treat NEURO CNS. It contains Valproic Acid (500mg), which Increases GABA levels in the brain by inhibiting GABA transaminase and enhancing. Always consult your doctor before use. Take as prescribed.
- Generic Name: Valproic Acid
- Manufacturer: A N Pharmacia
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ convulex 500mg tablet er Uses & Benefits
Epilepsy (partial and generalized seizures), bipolar disorder (mania), migraine prophylaxis.
Off-label uses: Neuropathic pain, status epilepticus (IV), borderline personality disorder, aggression in dementia.
๐ Drug Information
| Generic Name(s) | Valproic Acid |
| Brand Name | Alporate |
| Manufacturer | A N Pharmacia |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Sodium channel modulators (AED) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Increases GABA levels in the brain by inhibiting GABA transaminase and enhancing GABA synthesis; also blocks voltage-gated sodium channels and T-type calcium channels.
Mechanism Steps
๐ก How to Take convulex 500mg tablet er
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of convulex 500mg tablet er
โ Common Side Effects
- Nausea
- Vomiting
- Dizziness
- Somnolence
- Tremor
- Weight gain
- Hair loss
- Thrombocytopenia
๐จ Serious Side Effects
- Hepatotoxicity
- Pancreatitis
- Hyperammonemic encephalopathy
- Bone marrow suppression
- Stevens-Johnson syndrome
- QT prolongation
โ ๏ธ Rare Side Effects
- Polycystic ovary syndrome
- Encephalopathy
- Fanconi syndrome
- Hypothyroidism
- Vasculitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Carbamazepine | Major | Decreased valproate levels; increased risk of carbamazepine toxicity |
| Lamotrigine | Major | Increased lamotrigine levels; risk of Stevens-Johnson syndrome |
| Phenytoin | Major | Altered phenytoin levels; increased valproate toxicity |
| Warfarin | Moderate | Increased bleeding risk |
| Aspirin | Moderate | Increased valproate levels; bleeding risk |
| Alcohol | Moderate | Increased CNS depression and hepatotoxicity |
๐จ Major Interactions
- Carbamazepine
- Lamotrigine
- Phenytoin
- Phenobarbital
- Rifampin
- Topiramate
โก Moderate Interactions
- Aspirin
- Warfarin
- Cimetidine
- Erythromycin
- Fluoxetine
- Felbamate
โน๏ธ Minor Interactions
- Antacids
- Cholestyramine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Food may delay absorption; avoid alcohol.
๐ท Alcohol Interaction
Increased CNS depression and hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to valproate; hepatic disease or significant hepatic dysfunction; known urea cycle disorders; porphyria.
๐ Monitoring Parameters
Liver function tests, platelet count, serum valproate levels (therapeutic range: 50-100 mcg/mL), CBC, coagulation profile.
๐คฑ Lactation Safety
Valproic acid is excreted in breast milk; caution advised; risk of hepatotoxicity in infant.
๐ Overdose Management
Supportive care; activated charcoal if recent ingestion; hemodialysis may be effective; monitor for CNS depression, respiratory depression, and hepatic toxicity.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for convulex 500mg tablet er
View AllAlternative brands with exact same active ingredient (Valproic Acid (500mg)):
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epsoval 500mg tablet xrLa Pharmaceuticals โน52.89 35.5% CHEAPER
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novalept chrono 500mg tablet crAurum Life Science Pvt Ltd โน57.26 30.2% CHEAPER
-
soval 500mg tabletShine Pharmaceuticals Ltd โน61.73 24.7% CHEAPER
-
disoval 500mg tablet erLa Pharmaceuticals โน77.55 5.4% CHEAPER
-
valcot 500mg tablet crPsycormedies โน90.58 10.5% COSTLIER
-
ivalp 500mg tabletKivi Labs Ltd โน92.00 12.2% COSTLIER
-
welcorate 500mg tablet erWelgenic Pharma โน99.60 21.5% COSTLIER
-
alporate 500mg tabletAltius Life Sciences โน102.48 25% COSTLIER
-
genval 500mg tablet crGentech Healthcare Pvt Ltd โน105.00 28% COSTLIER
-
doncorate 500mg tablet erBondane Pharma โน110.00 34.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.