concor cor 5mg tablet - Bisoprolol (5mg) medicine

Bisobis 5mg Tablet (Bisoprolol 5mg): Complete Medicine Guide

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🏭 Merck Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Very slow heart rate (less than 50 beats per minute) or fainting
  • Severe dizziness or lightheadedness
  • Increased shortness of breath or swelling of ankles
  • Wheezing or difficulty breathing
  • Chest pain that is new or worsening
  • Yellowing of skin or eyes
  • Severe fatigue or weakness

If experiencing severe symptoms, call emergency services immediately.

What is concor cor 5mg tablet used for?

This medicine contains Bisoprolol 5 mg, a cardioselective beta-blocker used to treat high blood pressure, angina, and stable heart failure. It works by slowing the heart rate and reducing the heart's workload. It must be taken exactly as prescribed and should not be stopped suddenly.

  • Generic Name: Bisoprolol
  • Manufacturer: Merck Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 concor cor 5mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा बिसोप्रोलोल 5 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग उच्च रक्तचाप (हाइपरटेंशन), एंजाइना (सीने में दर्द), और स्थिर हृदय विफलता के इलाज के लिए किया जाता है। यह हृदय की गति को धीमा करके और हृदय पर पड़ने वाले दबाव को कम करके काम करती है। यह दवा केवल डॉक्टर के परामर्श से ही लेनी चाहिए और इसे अचानक बंद नहीं करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, हाथ-पैर ठंडे होना, धीमी हृदय गति, मतली और दस्त शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर ब्रैडीकार्डिया, हृदय विफलता का बिगड़ना, ब्रोंकोस्पाज्म और हृदय ब्लॉक शामिल हो सकते हैं। यदि आपको कोई भी असामान्य लक्षण महसूस हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एंजाइना बिगड़ सकता है या दिल का दौरा पड़ सकता है। यदि आपको अस्थमा, सीओपीडी, मधुमेह, थायरॉइड विकार, या गुर्दे या यकृत की समस्या है तो अपने डॉक्टर को बताएं। मधुमेह रोगियों में यह दवा लो ब्लड शुगर के लक्षणों को छिपा सकती है, इसलिए ब्लड शुगर की निगरानी करें। इस दवा के साथ शराब न लें। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन न चलाएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 concor cor 5mg tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine effectively lowers elevated blood pressure by reducing cardiac output and decreasing heart rate, thereby reducing the risk of stroke and heart attack.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"This medicine reduces the frequency and severity of angina attacks by decreasing myocardial oxygen demand and improving exercise tolerance.","evidence":"Well-established"},{"condition":"Stable chronic heart failure","description":"This medicine is used as an add-on therapy to standard heart failure treatment to reduce hospitalizations and improve survival in patients with stable chronic heart failure.","evidence":"Well-established"},{"condition":"Atrial fibrillation","description":"This medicine may be used to control heart rate in patients with atrial fibrillation, though it is not the first-line agent for all patients.","evidence":"Established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to reduce the frequency of migraine attacks, though evidence is limited compared to other beta-blockers.","evidence":"Limited"},{"condition":"Performance anxiety","description":"Occasionally used off-label to manage symptoms of performance anxiety such as tremors and rapid heart rate.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris, Stable chronic heart failure, Atrial fibrillation

📋 Drug Information

Generic Name(s)Bisoprolol
Brand NameBisoheart 2.5 Tablet
ManufacturerMerck Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassBeta blocker- Cardioselective
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Do not stop this medicine abruptly; your doctor will taper the dose gradually to prevent rebound angina or heart attack.
3
Monitor your heart rate and blood pressure regularly and report any significant changes to your doctor.
4
If you have diabetes, be aware that this medicine can mask symptoms of low blood sugar; monitor your glucose levels closely.
5
Inform your doctor if you have asthma or COPD, as this medicine can cause bronchospasm.
6
Avoid alcohol while taking this medicine as it can enhance dizziness and low blood pressure.
7
Report any signs of worsening heart failure such as increased shortness of breath, swelling of ankles, or sudden weight gain.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
✅
Chest pain (angina)
This medicine helps reduce angina attacks.
Likely Use
✅
Heart failure
This medicine is used as add-on therapy for stable heart failure.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBisoprolol is well absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability is approximately 88%.
DistributionBisoprolol is widely distributed throughout the body. It has a moderate volume of distribution of about 3.5 L/kg.
Protein BindingApproximately 30% of bisoprolol is bound to plasma proteins.
MetabolismBisoprolol undergoes minimal hepatic metabolism. About 50% of the dose is metabolized in the liver, primarily by CYP3A4 and CYP2D6 enzymes, but the metabolites are inactive.
Half-LifeThe elimination half-life of bisoprolol is approximately 10 to 12 hours.
ExcretionBisoprolol is excreted equally through the kidneys (50% as unchanged drug) and in the feces (50% as unchanged drug and metabolites).
BioavailabilityThe absolute bioavailability of bisoprolol is approximately 88%.
Onset of ActionThe onset of action of this medicine is typically within 1 to 2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 2 to 4 hours after oral administration.
Duration of ActionThe duration of action of this medicine is approximately 24 hours, allowing for once-daily dosing.

How It Works

This medicine selectively blocks beta-1 adrenergic receptors located primarily in the heart. By blocking these receptors, it reduces the effects of catecholamines such as adrenaline and noradrenaline on the heart. This leads to a decrease in heart rate, reduced force of cardiac contraction, and slower conduction through the atrioventricular node. These actions reduce myocardial oxygen demand and lower blood pressure, which is beneficial in hypertension, angina, and heart failure.

Mechanism Steps

1
Selective beta-1 receptor binding: This medicine binds selectively to beta-1 adrenergic receptors on the heart muscle and conduction system.
2
Inhibition of catecholamine effects: By occupying these receptors, it prevents adrenaline and noradrenaline from stimulating the heart.
3
Reduced heart rate and contractility: This leads to a slower heart rate and decreased force of heart muscle contraction, reducing cardiac workload.
4
Lowered myocardial oxygen demand: The reduced workload decreases the heart's need for oxygen, which helps relieve angina and improve heart failure symptoms.
5
Slowed AV conduction: This medicine also slows electrical conduction through the atrioventricular node, which can help control rapid heart rates in conditions like atrial fibrillation.

💡 How to Take concor cor 5mg tablet

Strength: Bisoprolol 5 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You can take it with or without food.
4Take it at the same time each day to maintain consistent blood levels.
5Do not crush, chew, or break the tablet unless your doctor advises otherwise.

Dosage Information

Adult DosageThe usual starting dose of this medicine for hypertension or angina is 5 mg once daily. The dose may be increased to 10 mg once daily based on response. For heart failure, the starting dose is usually 1.25 mg once daily, gradually increased to a maximum of 10 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance less than 20 mL/min), the dose should be reduced. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with severe hepatic impairment, the dose should be reduced. Dose must be individualized by a qualified clinician.
Maximum Daily Dose10 mg per day for hypertension and angina; 10 mg per day for heart failure.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time each day
Food does not significantly affect absorption.
Grapefruit juice
Avoid large amounts
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of concor cor 5mg tablet

✅ Common Side Effects

Tiredness (Common (up to 10%))
Usually improves with continued use. If persistent, consult your doctor.
Dizziness (Common (up to 10%))
Avoid driving or operating machinery until you know how this medicine affects you. Consult your doctor if it persists.
Headache (Common (up to 10%))
Usually resolves on its own. Consult your doctor if it is severe or persistent.
Cold hands or feet (Common (up to 10%))
Keep warm. Consult your doctor if it becomes bothersome.
Nausea (Common (up to 10%))
Take with food to reduce nausea. Consult your doctor if it persists.
Diarrhoea (Common (up to 10%))
Stay hydrated. Consult your doctor if it is severe or persistent.

🚨 Serious Side Effects

Severe bradycardia (very slow heart rate) (Uncommon (0.1-1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or a very slow pulse.
Worsening heart failure (Uncommon (0.1-1%))
Contact your doctor immediately if you experience increased shortness of breath, swelling of ankles, or sudden weight gain.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you develop wheezing, difficulty breathing, or chest tightness.
Heart block (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, palpitations, or severe dizziness.

⚠️ Rare Side Effects

Depression
Consult your doctor if you experience persistent low mood or loss of interest in activities.
Sleep disturbances
Consult your doctor if sleep problems persist or affect your daily life.
Skin rash
Consult your doctor if you develop a rash or itching.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Diltiazem Major
Clonidine Major
Digoxin Moderate
NSAIDs Moderate
Rifampicin Minor
Antacids Minor

🚨 Major Interactions

  • Verapamil or diltiazem
  • Clonidine
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Non-dihydropyridine calcium channel blockers
  • Digoxin
  • NSAIDs

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine and increase the risk of dizziness, lightheadedness, and fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe asthma or severe chronic obstructive pulmonary disease","Second or third degree heart block","Cardiogenic shock","Decompensated heart failure","Severe bradycardia","Untreated pheochromocytoma","Severe peripheral arterial disease"]

⚠️ Warnings & Precautions

["Do not stop this medicine abruptly; taper gradually under medical supervision.","Use with caution in patients with asthma or COPD; bronchospasm may occur.","May mask symptoms of hypoglycemia in diabetic patients.","May mask symptoms of hyperthyroidism.","Use with caution in patients with psoriasis or a history of psoriasis.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

Bisoprolol is excreted in human breast milk in small amounts. The amount ingested by the infant is unlikely to cause significant effects, but caution is advised. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Overdose of this medicine can cause severe bradycardia, hypotension, heart failure, and bronchospasm. If overdose is suspected, seek immediate medical attention. Treatment is supportive and may include atropine for bradycardia, intravenous fluids for hypotension, and beta-agonists for bronchospasm. In severe cases, glucagon or cardiac pacing may be required.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop this medicine suddenly on your own, as abrupt withdrawal can worsen angina or precipitate a heart attack. If you need to stop, your doctor will reduce the dose gradually over one to two weeks. Inform your doctor if you have asthma, chronic obstructive pulmonary disease, diabetes, thyroid disorders, or kidney or liver problems. This medicine can mask the symptoms of low blood sugar in diabetic patients, so monitor your blood glucose carefully. Avoid alcohol while taking this medicine as it may enhance the blood pressure-lowering effect and cause dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep all follow-up appointments and get your heart rate and blood pressure checked regularly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, especially bradycardia and hypotension. Start with a lower dose and titrate slowly. Regular monitoring of heart rate, blood pressure, and renal function is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before conception. This medicine is Pregnancy Category C and should be used only if clearly needed. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Do not stop the medicine unless instructed by your doctor.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Engage in regular low-impact exercise like walking or swimming, as advised by your doctor.
😴
Follow a heart-healthy diet low in salt and saturated fats.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep and maintain a regular sleep schedule.

🏋️ Exercise Considerations

This medicine can reduce your heart rate and blood pressure, which may affect your exercise capacity. Avoid strenuous activities until you know how the medicine affects you. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Reduce sodium intake to help control blood pressure.
Include plenty of fruits, vegetables, and whole grains.
Choose lean proteins and healthy fats.
Limit processed foods and sugary drinks.
Stay well hydrated unless your doctor advises otherwise.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once they adjust to the medicine.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your doctor decides to discontinue it, the dose will be reduced gradually to prevent complications.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups should include heart rate, blood pressure, and assessment of heart failure symptoms. Do not stop the medicine without medical advice. Long-term use may be necessary to control chronic conditions.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can complement medicine for managing hypertension and heart conditions.

Evidence: Well-established
Other beta-blockers

Metoprolol, atenolol, or carvedilol may be alternatives if bisoprolol is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Store at room temperature and protect from moisture. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure and angina
He was prescribed this medicine 5 mg once daily. After a few weeks, his blood pressure stabilized and angina attacks became less frequent. He initially felt tired but this improved after a month. He was advised not to stop the medicine suddenly.
💡 Lesson: Consistent daily dosing and gradual titration are key to getting the best results and avoiding withdrawal effects.
👤 A 68-year-old woman with stable heart failure
She started on a low dose of this medicine which was gradually increased. She noticed improved energy levels and less breathlessness over several months. She monitored her weight daily and reported any sudden gain to her doctor.
💡 Lesson: For heart failure, this medicine is started at a low dose and increased slowly. Daily weight monitoring helps detect fluid retention early.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 1-2 hours, but it may take several weeks to achieve full therapeutic effect.

Q: Can I stop taking this medicine suddenly?

A: No, stopping suddenly can worsen angina or cause a heart attack. Your doctor will taper the dose gradually.

Q: What should I do if I miss a dose?

A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.

Q: Is it safe to take this medicine during pregnancy?

A: It is Pregnancy Category C. Use only if the potential benefit justifies the risk. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for concor cor 5mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Bisoprolol can be stopped once blood pressure is normal.
    Fact: Bisoprolol controls blood pressure but does not cure hypertension. It should be continued as prescribed and stopped only under medical supervision.
  • Myth: Bisoprolol is safe for everyone with high blood pressure.
    Fact: Bisoprolol is not suitable for people with severe asthma, certain heart rhythm disorders, or decompensated heart failure.
  • Myth: Bisoprolol causes weight gain.
    Fact: Weight gain is not a common side effect of bisoprolol. Some patients may experience fluid retention due to heart failure, which should be reported to the doctor.

🔄 Alternative Options

Generic Alternatives

  • Bisoprolol 5 mg tablet

Brand Alternatives

  • Bisobis 5mg Tablet
  • Concor 5mg Tablet
  • Zebeta 5mg Tablet
  • Monocor 5mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Bisoprolol","class":"Cardioselective beta-1 blocker","primary_use":"Hypertension, angina, heart failure","half_life":"10-12 hours","notes":"Once-daily dosing; minimal hepatic metabolism."},{"medicine":"Metoprolol","class":"Cardioselective beta-1 blocker","primary_use":"Hypertension, angina, heart failure","half_life":"3-7 hours","notes":"Available as immediate and extended-release; twice-daily for immediate-release."},{"medicine":"Atenolol","class":"Cardioselective beta-1 blocker","primary_use":"Hypertension, angina","half_life":"6-7 hours","notes":"Renally excreted; dose adjustment in renal impairment."},{"medicine":"Carvedilol","class":"Non-selective beta-blocker with alpha-blocking activity","primary_use":"Heart failure, hypertension","half_life":"7-10 hours","notes":"Twice-daily dosing; more side effects due to alpha-blockade."}]

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