compaxin 250mg/250mg capsule - Ampicillin (250mg) + Cloxacillin (250mg) medicine

compaxin 250mg/250mg capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Hamax Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is compaxin 250mg/250mg capsule used for?

Ampoxin 500 Capsule (Ampicillin + Cloxacillin) is used to treat ANTI INFECTIVES. It contains Ampicillin (250mg) + Cloxacillin (250mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ampicillin + Cloxacillin
  • Manufacturer: Hamax Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š compaxin 250mg/250mg capsule Uses & Benefits

Respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections

Off-label uses: Prophylaxis in dental procedures, Endocarditis prophylaxis

๐Ÿ“‹ Drug Information

Generic Name(s)Ampicillin + Cloxacillin
Brand NameAmpoxin 500 Capsule
ManufacturerHamax Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillinase-resistant penicillin combination
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract
DistributionDistributed widely in body tissues and fluids, including pleural, peritoneal, and synovial fluids
Protein BindingAmpicillin: 15-25%; Cloxacillin: 90-95%
MetabolismPartially hepatic
Half-LifeAmpicillin: 1-1.5 hours; Cloxacillin: 0.5-1 hour
ExcretionRenal (tubular secretion and glomerular filtration)
BioavailabilityAmpicillin: 50-60%; Cloxacillin: 50-70%
Onset of Action1-2 hours
Peak Plasma Time1-2 hours
Duration of Action6-8 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis

Mechanism Steps

1Penetration through bacterial cell wall via porins
2Binding to penicillin-binding proteins (PBPs) on the inner membrane
3Inhibition of transpeptidase activity, preventing cross-linking of peptidoglycan

๐Ÿ’ก How to Take compaxin 250mg/250mg capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of compaxin 250mg/250mg capsule

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Urticaria

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Pseudomembranous colitis
  • Stevens-Johnson syndrome
  • Seizures

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Methotrexate Major Increased methotrexate toxicity
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of penicillins
Oral contraceptives Moderate Reduced contraceptive efficacy
Allopurinol Moderate Increased risk of skin rash
Chloramphenicol Moderate Antagonistic effect
Aminoglycosides Minor Physical incompatibility in vitro
Tetracyclines Minor Bacteriostatic antagonism

๐Ÿšจ Major Interactions

  • Methotrexate
  • Warfarin
  • Probenecid

โšก Moderate Interactions

  • Oral contraceptives
  • Allopurinol
  • Chloramphenicol

โ„น๏ธ Minor Interactions

  • Aminoglycosides
  • Tetracyclines

๐Ÿฝ๏ธ Food Interactions

Food may decrease absorption; take on empty stomach

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to penicillins, cephalosporins, or any component

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, complete blood count, signs of hypersensitivity

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may be considered

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

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