Allerfree Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is coldstat 2 mg/500 mg/60 mg tablet used for?
This medicine is a combination of Chlorpheniramine Maleate (an antihistamine) and Paracetamol (a pain reliever and fever reducer). It is used to treat symptoms of allergies and the common cold, such as sneezing, runny nose, itching, fever, and body ache. It is available as an oral tablet and should be taken as prescribed by a doctor.
- Generic Name: Chlorpheniramine Maleate + Paracetamol
- Manufacturer: Rusi Remedies P Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coldstat 2 mg/500 mg/60 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरफेनिरामाइन मेलिएट और पैरासिटामोल का संयोजन है। इसका उपयोग एलर्जी और सर्दी-जुकाम के लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली, बुखार और शरीर दर्द में राहत के लिए किया जाता है। यह दवा डॉक्टर के परामर्श से ही लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लीवर की समस्या या खून की बीमारी हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसके साथ शराब न लें। गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। यदि आपको लीवर या किडनी की बीमारी, ग्लूकोमा, प्रोस्टेट की समस्या या सांस लेने में तकलीफ है तो डॉक्टर को बताएं। 7 दिन से ज्यादा इसका इस्तेमाल बिना डॉक्टर की सलाह के न करें।
💊 coldstat 2 mg/500 mg/60 mg tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and watery eyes associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives due to allergic reactions.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from fever, body ache, and allergic symptoms like sneezing and runny nose.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Helps reduce eye itching and redness associated with allergies.","evidence":"Limited"}]
Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for its sedative effects to promote sleep, but not recommended due to side effects.","evidence":"Limited"},{"condition":"Motion sickness","description":"May be used off-label for prevention of motion sickness due to antihistamine properties.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Urticaria, Common cold, Allergic conjunctivitis
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Paracetamol |
| Brand Name | Alex P Syrup |
| Manufacturer | Rusi Remedies P Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in original container. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which leads to reduction of fever and pain. The combination provides both antihistaminic and analgesic-antipyretic effects.
Mechanism Steps
💡 How to Take coldstat 2 mg/500 mg/60 mg tablet
Strength: Each tablet contains Chlorpheniramine Maleate 2 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 1 tablet orally every 6 to 8 hours as needed for symptoms, not to exceed 4 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be required. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be required. Consult a doctor. |
| Maximum Daily Dose | Maximum 4 tablets in 24 hours (providing 2000 mg paracetamol and 8 mg chlorpheniramine). Do not exceed. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coldstat 2 mg/500 mg/60 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Warfarin | Moderate | |
| CNS depressants | Moderate | |
| Anticholinergics | Moderate | |
| Carbamazepine | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol
- Warfarin
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids)
- Anticholinergic drugs (e.g., tricyclic antidepressants)
- Carbamazepine
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of liver damage, especially with paracetamol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, paracetamol, or any component","Newborns and premature infants","Nursing mothers","Severe liver disease","Severe kidney disease","Patients taking MAOIs"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, enlarged prostate, or urinary retention.","Use with caution in elderly patients due to increased risk of confusion and falls.","Do not use for more than 7 days without consulting a doctor.","Do not exceed recommended dose of paracetamol; risk of liver damage.","Consult doctor if symptoms persist or worsen."]
🤱 Lactation Safety
Not recommended during breastfeeding as chlorpheniramine may pass into breast milk and cause drowsiness in the infant. Consult your doctor.
💊 Overdose Management
Overdose may cause severe liver damage, nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment includes gastric lavage, activated charcoal, and administration of acetylcysteine for paracetamol toxicity. Supportive care for antihistamine effects.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol and other central nervous system depressants while taking this medicine. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have liver or kidney disease, glaucoma, enlarged prostate, or breathing problems. Do not use for more than 7 days without consulting a doctor. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of chlorpheniramine. They may experience confusion, dizziness, and increased risk of falls. Use with caution and lower doses may be needed.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light exercise is generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is best to avoid these activities until you know how the medicine affects you. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver damage, especially with alcohol. Chlorpheniramine may cause tolerance and dependence. Regular monitoring of liver function may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Identifying and avoiding triggers can reduce allergy symptoms.
Evidence: Well-establishedHelps clear nasal passages and reduce congestion.
Evidence: Well-establishedLess sedating alternatives like cetirizine or loratadine may be preferred.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are unwell with a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it.
A: It can be taken with or without food, but taking it with food may reduce stomach upset.
A: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to children.
A: Consult your doctor before taking other medicines, as they may contain paracetamol or antihistamines, leading to overdose.
🤔 Common Patient Concerns
🔄 Substitutes for coldstat 2 mg/500 mg/60 mg tablet
View AllAlternative brands with exact same active ingredient:
-
active 2mg/500mg tabletAcichem Laboratories ₹2.25 91% CHEAPER
-
cp mol 2mg/500mg tabletSunrise International Labs ₹4.69 81.2% CHEAPER
-
c.p. mol tabletSun Pharmaceutical Industries Ltd ₹6.85 72.6% CHEAPER
-
specold tabletBen Pharmaceuticals ₹13.50 46% CHEAPER
-
anacold tabletMagnum Laboratories Pvt Ltd ₹13.51 46% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Allerfree Tablet is an antibiotic.
Fact: This medicine is not an antibiotic; it is a combination of an antihistamine and a pain reliever. - Myth: Allerfree Tablet can be taken long-term for allergies.
Fact: This medicine is for short-term symptomatic relief. Long-term use should be under medical supervision. - Myth: Allerfree Tablet is safe to take with alcohol.
Fact: Alcohol should be avoided as it increases drowsiness and risk of liver damage.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine Maleate + Paracetamol tablet
Brand Alternatives
- Allerfree Tablet