coldman tablet - Ambroxol (30mg) + Levocetirizine (2.5mg) medicine

Coldman Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Sundyota Numandis Probioceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Not established from the available information. The safety of this combination in pregnancy has not been well studied. Use only if clearly needed and after consulting your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or wheezing
  • Severe skin rash or blistering
  • Irregular or fast heartbeat
  • Severe dizziness or fainting
  • Yellowing of the eyes or skin
  • Blood in sputum or vomit
  • Persistent high fever

If experiencing severe symptoms, call emergency services immediately.

What is coldman tablet used for?

This medicine is a combination of Ambroxol (a mucolytic) and Levocetirizine (an antihistamine) used to treat productive cough with thick mucus and allergic symptoms. It helps loosen mucus and reduces sneezing, runny nose, and itching. It may cause drowsiness, so avoid driving. Take it exactly as prescribed by your doctor.

  • Generic Name: Ambroxol + Levocetirizine
  • Manufacturer: Sundyota Numandis Probioceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 coldman tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एम्ब्रोक्सोल और लेवोसेटिरिज़ीन का संयोजन है। इसका उपयोग गाढ़े बलगम वाली खांसी और एलर्जी के लक्षणों जैसे छींक, नाक बहना, खुजली और आंखों में पानी आना के इलाज में किया जाता है। एम्ब्रोक्सोल बलगम को पतला करके निकालने में मदद करता है, जबकि लेवोसेटिरिज़ीन एलर्जी के कारण होने वाले लक्षणों को कम करता है। यह दवा नींद ला सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें। इसे डॉक्टर के बताए अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, सिरदर्द और हल्का पेट दर्द शामिल हैं। कुछ लोगों को जी मिचलाना, चक्कर आना या कड़वा स्वाद भी महसूस हो सकता है। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ या गले में सूजन, सांस लेने में कठिनाई या त्वचा पर गंभीर दाने दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं। यह दवा नींद ला सकती है, इसलिए गाड़ी चलाने, मशीन चलाने या ध्यान देने वाले कामों से बचें जब तक आपको पता न चल जाए कि यह आप पर कैसा असर करती है। इस दवा के साथ शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अगर आपको किडनी या लीवर की समस्या है, तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के सूखी खांसी के लिए इस दवा का इस्तेमाल न करें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 coldman tablet Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"This medicine helps loosen and thin bronchial secretions, making it easier to cough out mucus in conditions such as acute or chronic bronchitis.","evidence":"Well-established for Ambroxol component"},{"condition":"Allergic rhinitis","description":"The Levocetirizine component reduces sneezing, runny nose, itching, and watery eyes associated with seasonal or perennial allergies.","evidence":"Well-established for Levocetirizine component"},{"condition":"Allergic cough with mucus","description":"This combination may be used when an allergic cough is accompanied by thick mucus, providing both antihistamine and mucolytic effects.","evidence":"Limited, based on clinical practice"}]

Off-label uses: [{"condition":"Chronic sinusitis with thick secretions","description":"Sometimes prescribed to help thin sinus secretions and reduce allergic symptoms, though not a primary approved indication.","evidence":"Limited"},{"condition":"Smoker's cough with mucus","description":"May be used to help clear mucus in chronic smokers, but smoking cessation remains the main treatment.","evidence":"Limited"}]

Primary treatment for: Productive cough with thick mucus and allergic rhinitis

Also treats: Acute bronchitis, Chronic bronchitis, Allergic cough, Seasonal allergic rhinitis

📋 Drug Information

Generic Name(s)Ambroxol + Levocetirizine
Brand NameAlerfix Total Tablet SR
ManufacturerSundyota Numandis Probioceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Antihistamine
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce the chance of stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects your alertness.
3
Do not drink alcohol while taking this medicine, as it can increase drowsiness.
4
If you have kidney or liver problems, inform your doctor before starting this medicine.
5
Do not use this medicine for a dry cough or for more than 7 days without medical advice.
6
Stay well hydrated to help loosen mucus and ease coughing.
7
Report any unusual mood changes, palpitations, or allergic reactions to your doctor promptly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing and runny nose
This medicine contains an antihistamine for allergic symptoms.
Likely Use
❌
Dry cough
This medicine is not primarily for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmbroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Levocetirizine is also rapidly and extensively absorbed after oral intake. Food does not significantly affect the extent of absorption of Levocetirizine, but it may slightly delay the time to peak concentration.
DistributionAmbroxol distributes widely into body tissues, including lung tissue, and crosses the blood-brain barrier to some extent. Levocetirizine distributes into body tissues, but its penetration into the central nervous system is limited because it is a peripheral H1 antagonist.
Protein BindingAmbroxol is approximately 80-90% bound to plasma proteins. Levocetirizine is about 90% bound to plasma proteins.
MetabolismAmbroxol is metabolized in the liver primarily by conjugation, forming inactive metabolites such as dibromanthranilic acid. Levocetirizine undergoes minimal metabolism in humans; a small fraction is metabolized by oxidation.
Half-LifeThe elimination half-life of Ambroxol is approximately 7-12 hours. The elimination half-life of Levocetirizine is approximately 6-10 hours in adults with normal kidney function.
ExcretionAmbroxol and its metabolites are mainly excreted in the urine. Levocetirizine is primarily excreted unchanged in the urine, with a smaller amount in feces.
BioavailabilityThe oral bioavailability of Ambroxol is approximately 70-80% due to first-pass metabolism. Levocetirizine has a high oral bioavailability of about 90% or more.
Onset of ActionAmbroxol's mucolytic effect may begin within 30-60 minutes after oral intake. Levocetirizine starts reducing allergic symptoms within 1 hour, with noticeable relief often within 1-2 hours.
Peak Plasma TimeAmbroxol reaches peak plasma concentration about 1-3 hours after oral administration. Levocetirizine reaches peak plasma concentration about 0.9-1.5 hours after oral administration.
Duration of ActionAmbroxol's mucolytic effect lasts approximately 6-8 hours, requiring multiple daily doses. Levocetirizine's antihistamine effect lasts about 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two active ingredients with different mechanisms. Ambroxol acts as a mucolytic and secretolytic agent; it increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production, which helps mucus move more easily. It also has local anesthetic and antioxidant properties. Levocetirizine is the active enantiomer of cetirizine and works as a selective peripheral H1-receptor antagonist. By blocking histamine at H1 receptors, it reduces allergic symptoms such as sneezing, itching, and nasal discharge. Together, these actions help relieve cough associated with thick mucus and allergic symptoms.

Mechanism Steps

1
Ambroxol enhances serous secretion: Ambroxol stimulates serous cells in the respiratory tract to produce more watery secretions, which helps thin thick mucus.
2
Ambroxol reduces mucus viscosity: By breaking down acidic mucopolysaccharide fibers, Ambroxol lowers mucus stickiness and makes it easier to expel.
3
Ambroxol promotes surfactant production: Ambroxol increases surfactant synthesis in type II pneumocytes, which helps keep airways open and aids mucus transport.
4
Levocetirizine blocks H1 receptors: Levocetirizine selectively binds to peripheral H1 receptors, preventing histamine from triggering allergic symptoms.
5
Reduced allergic inflammation: By blocking histamine, Levocetirizine decreases sneezing, itching, runny nose, and swelling in the nasal passages.

💡 How to Take coldman tablet

Strength: Tablet containing Ambroxol 30 mg and Levocetirizine 2.5 mg.

1Take this medicine by mouth with a glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew it unless your doctor advises otherwise.
4Take it at the same time each day to maintain consistent levels.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily, or as directed by your doctor. The exact dose and frequency depend on the condition being treated, your age, kidney and liver function, and other medicines you may be taking. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Dose adjustment may be needed based on kidney function. Consult a doctor for appropriate dosing.
Renal ImpairmentIn patients with kidney impairment, the dose of Levocetirizine may need to be reduced. For moderate renal impairment, a lower dose or less frequent dosing may be advised. In severe renal impairment, this medicine is contraindicated. Consult a doctor for dose adjustment.
Hepatic ImpairmentNo specific dose adjustment is established for mild to moderate liver impairment. In severe liver disease, use with caution and consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet twice daily, but this must be confirmed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit juice
Avoid large amounts
May affect drug metabolism, though specific interaction is not well established.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of coldman tablet

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you. If drowsiness is persistent, consult your doctor.
Dry mouth (Common (5-10%))
Sip water regularly or chew sugar-free gum. If it becomes bothersome, talk to your doctor.
Fatigue (Common (5-10%))
Ensure adequate rest. If fatigue interferes with daily activities, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, seek medical advice.
Nausea (Uncommon (1-5%))
Take the medicine with food to reduce stomach upset. If nausea continues, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a widespread rash.
Severe skin reactions (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you develop blistering, peeling skin, or sores in the mouth.
Palpitations or irregular heartbeat (Rare (<0.1%))
Consult a doctor promptly if you notice a fast, fluttering, or irregular heartbeat.

⚠️ Rare Side Effects

Mood changes or agitation
Report to your doctor if you experience unusual mood swings, aggression, or confusion.
Liver enzyme elevation
Your doctor may monitor liver function if you take this medicine for a long time. Report yellowing of eyes or skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Benzodiazepines Major
Opioid pain relievers Major
Tricyclic antidepressants Moderate
Ritonavir Moderate
Theophylline Minor
Antacids Minor

🚨 Major Interactions

  • Alcohol
  • CNS depressants (e.g., benzodiazepines, opioids, sleep aids)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Ritonavir

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to concentrate. Combining alcohol with Levocetirizine may also increase the risk of central nervous system depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Ambroxol, Levocetirizine, or any component of this medicine","Severe renal impairment (creatinine clearance less than 10 mL/min)","Children under 6 years of age (unless specifically prescribed by a pediatrician)","Pregnancy and breastfeeding (unless advised by a doctor)"]

⚠️ Warnings & Precautions

["This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Use with caution in patients with kidney or liver disease.","Do not use for a dry, non-productive cough without medical advice.","Consult a doctor if symptoms persist beyond 7 days or worsen.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. It is not known whether Ambroxol or Levocetirizine pass into breast milk in significant amounts. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine may cause increased drowsiness, dizziness, nausea, and in severe cases, agitation or difficulty breathing. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Contact a poison control center or emergency department right away.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Because this medicine can cause drowsiness, avoid driving, operating heavy machinery, or performing activities that require full alertness until you know how it affects you. Avoid drinking alcohol while taking this medicine, as it can increase drowsiness and impair your ability to think clearly. If you have kidney or liver problems, tell your doctor before starting this medicine, as the dose may need adjustment. Do not use this medicine for a dry, non-productive cough without medical advice. Keep this medicine out of the reach of children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the drowsiness and dizziness caused by this medicine. They may also have reduced kidney function, which can affect drug clearance. Dose adjustment may be needed. Consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. The safety of this combination in pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before taking this medicine. It may interact with other medications or affect your recovery. Do not self-medicate.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. The antihistamine component may cause dry mouth, which can affect dental health. Stay hydrated.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help loosen mucus.
🥗
Avoid smoking and exposure to secondhand smoke.
😴
Use a humidifier to keep indoor air moist.
💧
Get plenty of rest to support your immune system.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid known allergens that trigger your symptoms.

🏋️ Exercise Considerations

This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities that require full alertness until you know how it affects you. Light exercise like walking may be fine if you feel well.

🥗 Diet Recommendations

Drink warm fluids like herbal tea or warm water with honey to soothe your throat.
Include vitamin C-rich fruits and vegetables.
Avoid cold drinks and ice cream if they worsen your cough.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or concentrate at work. Avoid these activities until you know how the medicine affects you. If your job requires alertness, discuss with your doctor about timing your dose.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use may increase the risk of side effects such as drowsiness, dry mouth, and rarely, liver enzyme changes. Regular monitoring of kidney and liver function may be advised if used for extended periods. Do not use it for more than 7 days without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established for symptom relief
Saline nasal irrigation

Can help clear nasal passages and reduce allergy symptoms.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease allergic symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust your dosing schedule gradually as advised by your doctor. Check local customs regulations regarding prescription medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with seasonal allergies and a productive cough
He was prescribed this medicine for his cough and allergic symptoms. After taking it as directed with food, he noticed his cough became more productive and his sneezing reduced within two days. He experienced mild drowsiness initially, so he avoided driving until it subsided.
💡 Lesson: Taking this medicine with food and avoiding driving until you know its effects can improve tolerability and safety.
👤 A 50-year-old woman with chronic bronchitis
She used this medicine for her thick mucus cough. It helped loosen the mucus, making it easier to cough out. She was advised to drink plenty of water and avoid alcohol. She reported no serious side effects but did experience dry mouth, which was managed by sipping water regularly.
💡 Lesson: Staying hydrated and following safety advice can enhance the benefits of this medicine and minimize side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 1-2 hours. Ambroxol begins thinning mucus within 30-60 minutes, while Levocetirizine reduces allergic symptoms within 1 hour.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.

Q: Can I take this medicine during pregnancy?

A: The safety of this medicine in pregnancy is not well established. Consult your doctor before using it if you are pregnant or planning pregnancy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for coldman tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is an antibiotic.
    Fact: This medicine is not an antibiotic. It contains Ambroxol, a mucolytic, and Levocetirizine, an antihistamine. It does not kill bacteria.
  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is specifically for productive cough with thick mucus and allergic symptoms. It is not effective for dry cough or cough due to other causes.
  • Myth: It is safe to take this medicine with alcohol.
    Fact: Alcohol can increase drowsiness and dizziness caused by this medicine. It is best to avoid alcohol while taking it.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Levocetirizine combination tablets from other manufacturers

Brand Alternatives

  • Coldman Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Ambroxol + Levocetirizine)","composition":"Ambroxol 30 mg + Levocetirizine 2.5 mg","primary_use":"Productive cough with mucus and allergic rhinitis","sedation":"Moderate","frequency":"Once or twice daily"},{"medicine":"Ambroxol + Cetirizine","composition":"Ambroxol 30 mg + Cetirizine 5 mg","primary_use":"Productive cough with mucus and allergic symptoms","sedation":"Moderate to high","frequency":"Once or twice daily"},{"medicine":"Levocetirizine alone","composition":"Levocetirizine 5 mg","primary_use":"Allergic rhinitis, urticaria","sedation":"Low to moderate","frequency":"Once daily"}]

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