Ambrohist Plus Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is colace plus syrup used for?
This medicine is a combination cough syrup containing guaifenesin and ambroxol. It works by thinning and loosening mucus in the airways, making it easier to cough out. It is used for productive cough and should be taken as prescribed by a doctor.
- Generic Name: Guaifenesin + Ambroxol
- Manufacturer: Capricorn Biotech
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 colace plus syrup के बारे में (Hindi Summary)
उपयोग: यह दवा गुआइफेनेसिन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग बलगम वाली खांसी के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है। यह तीव्र और दीर्घकालिक ब्रोंकाइटिस, सीओपीडी जैसी स्थितियों में उपयोगी है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी प्रतिक्रिया या सांस लेने में कठिनाई हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुद से दवा की मात्रा न बढ़ाएं। इस दवा को लेते समय भरपूर पानी पिएं। अगर आपको चक्कर या नींद आती है तो वाहन चलाने या मशीन चलाने से बचें। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से परामर्श करें।
💊 colace plus syrup Uses & Benefits
[{"condition":"Productive cough","description":"Helps loosen and thin mucus, making it easier to cough out.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Provides symptomatic relief by clearing chest congestion.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage thick secretions in chronic obstructive pulmonary disease (COPD) and chronic bronchitis.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to help thin mucus in sinus infections, but not a primary treatment.","evidence":"Limited"}]
Primary treatment for: Productive cough
Also treats: Acute bronchitis, Chronic bronchitis, COPD
📋 Drug Information
| Generic Name(s) | Guaifenesin + Ambroxol |
| Brand Name | Ambrohist Plus Syrup |
| Manufacturer | Capricorn Biotech |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Expectorant and Mucolytic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions, helping to clear mucus. Ambroxol is a mucolytic that breaks down acidic mucopolysaccharide fibers in mucus, reducing its thickness and making it easier to expel. Together, they improve mucus clearance from the airways.
Mechanism Steps
💡 How to Take colace plus syrup
Strength: Each 5 ml contains Guaifenesin 50 mg and Ambroxol 15 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5-10 ml (1-2 teaspoons) every 4-6 hours, as needed, not to exceed 60 ml in 24 hours. However, the dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not self-medicate; follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and follow your doctor's advice. |
| Renal Impairment | Dose adjustment may be needed in patients with severe renal impairment. Consult your doctor. |
| Hepatic Impairment | Dose adjustment may be needed in patients with severe hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose for adults is 60 ml of this syrup in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of colace plus syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Codeine | Major | |
| Dextromethorphan | Major | |
| Amoxicillin | Moderate | |
| Cefuroxime | Moderate | |
| Furosemide | Moderate | |
| Atropine | Minor |
🚨 Major Interactions
- Cough suppressants (e.g., codeine, dextromethorphan)
⚡ Moderate Interactions
- Antibiotics (e.g., amoxicillin, cefuroxime)
- Diuretics
🍷 Alcohol Interaction
Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to guaifenesin, ambroxol, or any component of the formulation.","Children under 2 years of age.","Severe hepatic impairment.","Severe renal impairment.","Active peptic ulcer disease."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Use with caution in patients with a history of peptic ulcer.","Use with caution in patients with kidney or liver disease.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Consult a doctor if cough persists for more than 7 days, or if it is accompanied by fever, rash, or persistent headache.","Do not use in children under 2 years without medical advice.","If you are pregnant or breastfeeding, consult your doctor before use."]
🤱 Lactation Safety
It is not known whether guaifenesin and ambroxol pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it may lead to drowsiness, dizziness, and difficulty breathing. Seek immediate medical attention if overdose is suspected. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Drink plenty of water while taking this medicine to help loosen mucus. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not take this medicine for more than 7 days without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking this medicine. Keep this medicine out of reach of children. Do not use this medicine if you are allergic to guaifenesin, ambroxol, or any other ingredients. If you have a history of stomach ulcers or kidney/liver problems, tell your doctor before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects, especially drowsiness and dizziness. Use with caution and monitor for any adverse effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before taking this medicine, as it may affect cough reflexes and mucus clearance.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may affect saliva production and cause dry mouth.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or drowsiness after taking this medicine, avoid exercising or operating machinery until you feel alert.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, or if you experience severe side effects. Do not stop abruptly if you are on a prescribed course without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not recommended without medical supervision. Prolonged use may mask underlying conditions. Monitor for any persistent side effects. Regular review by a doctor is advised if used for chronic conditions.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help loosen mucus and relieve congestion.
Evidence: Well-establishedHelps clear nasal passages and reduce postnasal drip.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, if you have a fever or acute illness, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label. Bring a copy of your prescription in case of customs checks. Store at room temperature and avoid extreme heat or cold. If crossing time zones, continue your regular dosing schedule as prescribed. Keep the bottle tightly closed and upright to prevent leakage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to 1 hour after taking it.
A: Yes, but inform your doctor. Ambroxol may increase the concentration of some antibiotics in the lungs, which can be beneficial.
A: It is not recommended for children under 2 years. For older children, consult a pediatrician for appropriate dosing.
🤔 Common Patient Concerns
🔄 Substitutes for colace plus syrup
View AllAlternative brands with exact same active ingredient:
-
lictum a syrupPerk Pharmaceuticals Ltd ₹15.68 83.3% CHEAPER
-
bronkasma-kid syrupBevit Pharmaceuticals Ltd ₹17.00 81.9% CHEAPER
-
maxol syrupMalar Healthcare ₹28.08 70% CHEAPER
-
ecof-am syrupReco Drugs ₹30.00 68% CHEAPER
-
muconil syrupMaan Pharmaceuticals Ltd ₹30.00 68% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is only for productive cough with thick mucus. It is not effective for dry cough or cough due to allergies. - Myth: More medicine means faster relief.
Fact: Taking more than the recommended dose can increase side effects and does not provide faster relief. - Myth: It is safe to take this medicine with other cough syrups.
Fact: Combining with other cough medicines, especially suppressants, can be harmful. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Guaifenesin + Ambroxol syrup (various manufacturers)
Brand Alternatives
- Ambrodil-G
- Mucolite
- Brozeet-LS