cofsol expectorant - Ambroxol (30mg) + Menthol (5mg) medicine

cofsol expectorant - Uses, Price, Side Effects & Substitutes

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๐Ÿญ MDC Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is cofsol expectorant used for?

Ambrex Syrup (Ambroxol + Menthol) is used to treat RESPIRATORY. It contains Ambroxol (30mg) + Menthol (5mg), which Increases secretion of respiratory tract fluid, reduces mucus viscosity, and enh. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ambroxol + Menthol
  • Manufacturer: MDC Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š cofsol expectorant Uses & Benefits

Acute and chronic respiratory diseases with thick mucus, such as bronchitis, asthma, COPD, pneumonia

Off-label uses: None commonly reported

๐Ÿ“‹ Drug Information

Generic Name(s)Ambroxol + Menthol
Brand NameAmbrex Syrup
ManufacturerMDC Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Expectorant
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues, including lungs
Protein BindingApproximately 90%
MetabolismHepatic, primarily via glucuronidation
Half-Life7-12 hours
ExcretionRenal (90% as metabolites, 10% unchanged)
Bioavailability70-80%
Onset of Action30 minutes
Peak Plasma Time1-2 hours
Duration of Action6-12 hours

How It Works

Increases secretion of respiratory tract fluid, reduces mucus viscosity, and enhances mucociliary clearance

Mechanism Steps

1Stimulates serous cells in respiratory tract to increase fluid secretion
2Reduces mucus viscosity by breaking down mucopolysaccharide fibers
3Enhances ciliary beat frequency and mucociliary clearance

๐Ÿ’ก How to Take cofsol expectorant

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cofsol expectorant

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Rash

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Stevens-Johnson syndrome (rare)

โš ๏ธ Rare Side Effects

  • Gastrointestinal ulceration
  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โšก Moderate Interactions

  • Anticholinergics
  • Cough suppressants (e.g., codeine)

๐Ÿท Alcohol Interaction

No significant interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ambroxol or menthol, peptic ulcer (rare), severe hepatic or renal impairment

๐Ÿ“Š Monitoring Parameters

Respiratory symptoms, sputum characteristics, liver and renal function in long-term use

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution

๐Ÿ’Š Overdose Management

Induce vomiting or gastric lavage; symptomatic and supportive treatment

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

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