Bronki Syrup Sugar Free: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or worsening of breathing after taking the medicine
- Severe allergic reaction: rash, itching, swelling of face, lips, tongue, or throat
- Irregular or very fast heartbeat
- Chest pain or tightness
- Severe dizziness or fainting
- Yellowing of skin or eyes (jaundice)
- Decreased urine output
- Severe stomach pain or vomiting blood
If experiencing severe symptoms, call emergency services immediately.
What is coflin syrup used for?
This medicine is a sugar-free syrup containing terbutaline (a bronchodilator) and ambroxol (a mucolytic). It is used to treat respiratory conditions like bronchitis and asthma by relaxing airways and thinning mucus, making it easier to breathe and cough. It is available by prescription only.
- Generic Name: Terbutaline + Ambroxol
- Manufacturer: A. Menarini India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coflin syrup के बारे में (Hindi Summary)
उपयोग: यह दवा टर्ब्यूटलाइन और एम्ब्रोक्सोल का संयोजन है, जिसका उपयोग श्वसन संबंधी समस्याओं जैसे ब्रोंकाइटिस, अस्थमा और कफ के इलाज में किया जाता है। टर्ब्यूटलाइन श्वास नलियों की मांसपेशियों को आराम देकर सांस लेना आसान बनाती है, जबकि एम्ब्रोक्सोल बलगम को पतला करके बाहर निकालने में मदद करता है। यह शुगर-फ्री सिरप है, इसलिए मधुमेह रोगी भी इसका उपयोग कर सकते हैं। यह दवा डॉक्टर के पर्चे पर ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कंपन, बेचैनी, सिरदर्द, चक्कर आना, जी मिचलाना, उल्टी, पेट में असुविधा और हृदय गति बढ़ना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, अनियमित दिल की धड़कन, सीने में दर्द या सांस लेने में कठिनाई हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक बढ़ाएं या घटाएं नहीं। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मापने वाले कप या चम्मच का उपयोग करें। दवा को भोजन के साथ लेने से पेट की परेशानी कम होती है। अगर आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड या दौरे की समस्या है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। शराब का सेवन न करें। बच्चों की पहुंच से दूर रखें।
💊 coflin syrup Uses & Benefits
[{"condition":"Bronchitis","description":"Helps relieve bronchospasm and loosen mucus, making breathing easier and reducing cough.","evidence":"Well-established"},{"condition":"Asthma","description":"Used as a bronchodilator to relieve acute bronchospasm and as an adjunct in managing asthma symptoms.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May help relieve bronchospasm and facilitate mucus clearance in some patients.","evidence":"Limited"},{"condition":"Productive cough","description":"Ambroxol thins mucus, making it easier to cough up, while terbutaline helps open airways.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Preterm labor inhibition","description":"Terbutaline has been used off-label to delay preterm labor, but this is not a recommended use due to safety concerns.","evidence":"Limited"}]
Primary treatment for: Bronchitis
Also treats: Asthma, COPD, Productive cough
📋 Drug Information
| Generic Name(s) | Terbutaline + Ambroxol |
| Brand Name | Astharid Plus Tablet |
| Manufacturer | A. Menarini India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Bronchodilator + Mucolytic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place, away from direct sunlight. Do not freeze. Keep the bottle tightly closed. Use within the recommended period after opening. |
| Shelf Life | 24 months from the date of manufacture. After opening, use within 1 month if not specified otherwise. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Terbutaline is a selective beta-2 adrenergic receptor agonist that binds to beta-2 receptors in the smooth muscle of the airways, leading to relaxation and bronchodilation. Ambroxol is a mucolytic agent that reduces mucus viscosity by breaking down acidic mucopolysaccharide fibers and stimulating surfactant production, thereby facilitating mucus clearance. Together, they address both bronchospasm and mucus plugging in respiratory conditions.
Mechanism Steps
💡 How to Take coflin syrup
Strength: Each 5 ml contains Terbutaline 1.25 mg and Ambroxol 15 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5-10 ml (1-2 teaspoons) taken two to three times a day, or as directed by your doctor. The dose may vary depending on the condition being treated and your response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of terbutaline, especially cardiovascular effects. Use with caution and start with a lower dose. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 30 ml (6 teaspoons) in divided doses, but this may vary based on medical advice. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coflin syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Furosemide | Moderate | |
| Corticosteroids | Moderate | |
| Theophylline | Moderate | |
| Digoxin | Moderate | |
| Ipratropium | Minor | |
| Amoxicillin | Minor | |
| Cefuroxime | Minor |
🚨 Major Interactions
- Beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Corticosteroids
- Xanthine derivatives (e.g., theophylline)
- Digoxin
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and may exacerbate cardiovascular side effects such as rapid heart rate. It may also increase the risk of stomach upset.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to terbutaline, ambroxol, or any component of the formulation","Severe cardiovascular disease, including arrhythmias and severe coronary insufficiency","Uncontrolled hypertension","Hyperthyroidism","Severe hepatic or renal impairment (relative contraindication)","Pregnancy (especially first trimester) unless clearly needed","Breastfeeding (relative contraindication)"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease, including coronary insufficiency, arrhythmias, and hypertension.","Use with caution in patients with diabetes mellitus; terbutaline may increase blood glucose levels.","Use with caution in patients with hyperthyroidism; terbutaline may exacerbate symptoms.","Use with caution in patients with seizure disorders; terbutaline may lower seizure threshold.","Use with caution in patients with severe hepatic or renal impairment; dose adjustment may be needed.","Do not exceed the recommended dose; excessive use may lead to tolerance and increased side effects.","If you experience paradoxical bronchospasm (worsening of breathing), stop the medicine and seek medical help immediately.","Keep out of reach of children.","Do not use if the solution is discolored or contains particles.","Inform your doctor if you are taking any other medications, especially beta-blockers, MAOIs, or tricyclic antidepressants."]
🤱 Lactation Safety
Terbutaline is excreted in breast milk and may cause side effects in a nursing infant. Ambroxol is also excreted in breast milk. Consult your doctor before breastfeeding while taking this medicine. Your doctor will weigh the benefits and risks.
💊 Overdose Management
Overdose may cause severe tremors, palpitations, tachycardia, arrhythmias, hypertension, hypokalemia, and hyperglycemia. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor cardiac function, electrolytes, and blood glucose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your doctor. Shake the bottle well before each use. Use a proper measuring cup or spoon to measure the dose accurately. Do not use this medicine for a longer period than recommended. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or seizures. Tell your doctor about all other medicines you are taking, including over-the-counter products. Avoid alcohol while taking this medicine as it may increase drowsiness and dizziness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the cardiovascular effects of terbutaline, such as increased heart rate and palpitations. They may also be more prone to dizziness and falls. Use with caution and start with a lower dose. Regular monitoring of heart rate and blood pressure is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Terbutaline is not recommended during pregnancy unless clearly needed. Discuss alternative treatments and ensure any underlying respiratory condition is well managed before conception.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. Terbutaline can affect heart rate and blood pressure, which may interact with anesthetic agents. Your doctor will advise whether to continue or temporarily stop the medicine before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may cause dry mouth or increase heart rate, which can be relevant during dental work. Your dentist may take precautions, especially if you have heart conditions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you are experiencing acute respiratory symptoms. Gentle activities like walking may be beneficial once symptoms improve. Consult your doctor before resuming intense exercise, especially if you have asthma or heart disease.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or tremors, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest and avoid strenuous work while you are unwell. If your symptoms persist, consult your doctor for further evaluation.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience severe allergic reactions, irregular heartbeat, chest pain, or worsening of breathing. Do not stop the medicine abruptly without consulting your doctor, as some conditions may require gradual tapering. Follow your doctor's advice on the duration of treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance to terbutaline, reducing its effectiveness. It may also cause increased heart rate, tremors, and nervousness. Prolonged use of ambroxol is generally well tolerated but may rarely cause gastrointestinal upset. Regular monitoring of heart rate, blood pressure, and potassium levels is advised if used for extended periods. Do not use for longer than recommended without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and soothe airways.
Evidence: Traditional, limited scientific evidenceCan help clear nasal passages and reduce postnasal drip.
Evidence: ModerateTechniques to help clear mucus from the lungs.
Evidence: Well-established for certain conditions💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are acutely ill with fever, it is generally advisable to postpone vaccination until you recover. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in a cool, dry place, away from direct sunlight. If traveling across time zones, adjust dosing times gradually; consult your doctor for specific advice. Keep it in your carry-on luggage to avoid temperature extremes in checked baggage. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to 1 hour after oral administration. You may notice easier breathing and loosening of mucus.
A: Yes, it is best taken with food to reduce stomach upset. Avoid caffeine and alcohol.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed and prescribed by a doctor.
A: Do not stop without consulting your doctor. Complete the prescribed course to prevent recurrence of symptoms.
🤔 Common Patient Concerns
🔄 Substitutes for coflin syrup
View AllAlternative brands with exact same active ingredient:
-
Tussquit XP ExpectorantZeytin Pharma Pvt Ltd ₹45.47 7.8% COSTLIER
-
mucobust-a syrupMetamorf Lifesciences ₹56.25 33.3% COSTLIER
-
bronki syrup sugar freeSystacare Remedies ₹64.69 53.3% COSTLIER
-
karkof ax syrupArkle Healthcare Pvt Ltd ₹79.69 88.9% COSTLIER
-
ojtoux syrupOjal Pharmaceuticals Pvt Ltd ₹79.69 88.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure asthma permanently.
Fact: This medicine provides symptomatic relief but does not cure asthma. Asthma management requires a comprehensive plan. - Myth: This medicine is safe for everyone.
Fact: It is not safe for individuals with certain heart conditions, uncontrolled hypertension, or hyperthyroidism. Always consult a doctor. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You should complete the prescribed course or follow your doctor's advice before stopping, as abrupt discontinuation may worsen symptoms. - Myth: This medicine can be used for any type of cough.
Fact: It is specifically for productive cough associated with bronchospasm. It is not effective for dry cough or cough due to other causes.
🔄 Alternative Options
Generic Alternatives
- Terbutaline + Ambroxol syrup (various manufacturers)
Brand Alternatives
- Bronki Syrup Sugar Free (Systacare Remedies)