cofdex plus syrup sweet orange - Uses, Price, Side Effects & Substitutes
What is cofdex plus syrup sweet orange used for?
Amotus Syrup (Ammonium Chloride + Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Ammonium Chloride (60mg) + Chlorpheniramine Maleate (2.5mg), which Ammonium Chloride: Increases respiratory tract fluid, reduces mucus viscosity; C. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ammonium Chloride + Chlorpheniramine Maleate
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cofdex plus syrup sweet orange Uses & Benefits
Symptomatic relief of cough associated with respiratory tract infections, allergic rhinitis, common cold
Off-label uses: Sedation, Motion sickness
๐ Drug Information
| Generic Name(s) | Ammonium Chloride + Chlorpheniramine Maleate |
| Brand Name | Amotus Syrup |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Expectorant and Antihistamine |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Ammonium Chloride: Increases respiratory tract fluid, reduces mucus viscosity; Chlorpheniramine: Competitively blocks histamine H1 receptors
Mechanism Steps
๐ก How to Take cofdex plus syrup sweet orange
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cofdex plus syrup sweet orange
โ Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth
- Nausea
- Thickened bronchial secretions
๐จ Serious Side Effects
- Respiratory depression
- Severe hypotension
- Arrhythmias
- Seizures
- Urinary retention
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Anaphylaxis
- Hepatotoxicity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis, increased anticholinergic effects |
| CNS Depressants | Major | Additive sedation and respiratory depression |
| Alcohol | Major | Enhanced CNS depression |
| Anticholinergics | Moderate | Additive anticholinergic effects |
| Tricyclic Antidepressants | Moderate | Increased anticholinergic and sedative effects |
| Antihypertensives | Minor | Possible reduced antihypertensive effect |
| Diuretics | Minor | Possible electrolyte imbalance |
๐จ Major Interactions
- MAOIs
- CNS Depressants
- Alcohol
โก Moderate Interactions
- Anticholinergics
- Tricyclic Antidepressants
โน๏ธ Minor Interactions
- Antihypertensives
- Diuretics
๐ฝ๏ธ Food Interactions
None significant
๐ท Alcohol Interaction
Increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component, severe hypertension, coronary artery disease, MAOI use within 14 days, narrow-angle glaucoma, urinary retention, peptic ulcer, asthma attack
๐ Monitoring Parameters
Respiratory status, CNS depression, anticholinergic effects, blood pressure
๐คฑ Lactation Safety
Caution; Chlorpheniramine excreted in breast milk
๐ Overdose Management
Induce emesis or gastric lavage; administer activated charcoal; supportive care; for severe anticholinergic symptoms, physostigmine may be used
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose