coec 250mg tablet - Uses, Price, Side Effects & Substitutes
What is coec 250mg tablet used for?
Amloquin DS 250mg Tablet (Chloroquine) is used to treat OPHTHAL. It contains Chloroquine (250mg), which Inhibits heme polymerase in malarial parasites, leading to accumulation of toxic. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chloroquine
- Manufacturer: Elikem Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ coec 250mg tablet Uses & Benefits
Malaria (treatment and prophylaxis), amebic hepatitis, lupus erythematosus, rheumatoid arthritis (off-label).
Off-label uses: Rheumatoid arthritis, lupus erythematosus, sarcoidosis, porphyria cutanea tarda.
๐ Drug Information
| Generic Name(s) | Chloroquine |
| Brand Name | Amloquin DS 250mg Tablet |
| Manufacturer | Elikem Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Antimalarial- Aminoquinolines |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits heme polymerase in malarial parasites, leading to accumulation of toxic heme; also has anti-inflammatory and immunosuppressive effects.
Mechanism Steps
๐ก How to Take coec 250mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of coec 250mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal cramps
- Headache
- Dizziness
- Blurred vision
- Pruritus
๐จ Serious Side Effects
- Retinopathy
- Cardiomyopathy
- QT prolongation
- Seizures
- Bone marrow suppression
- Hepatotoxicity
- Neuromyopathy
โ ๏ธ Rare Side Effects
- Hemolytic anemia (G6PD deficiency)
- Agranulocytosis
- Stevens-Johnson syndrome
- Photosensitivity
- Hearing loss
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | Increased risk of cardiotoxicity |
| Cimetidine | Major | Increased chloroquine levels |
| Cyclosporine | Major | Increased cyclosporine levels |
| Digoxin | Major | Increased digoxin levels |
| Mefloquine | Major | Increased risk of seizures |
| Penicillamine | Major | Increased risk of hematologic toxicity |
| Tamoxifen | Major | Increased risk of retinopathy |
| Antacids | Moderate | Decreased absorption of chloroquine |
| Kaolin | Moderate | Decreased absorption of chloroquine |
| Magnesium trisilicate | Moderate | Decreased absorption of chloroquine |
| Corticosteroids | Moderate | Increased risk of immunosuppression |
| Insulin | Moderate | Increased hypoglycemic effect |
| Antidiabetic agents | Moderate | Increased hypoglycemic effect |
| Alcohol | Minor | Increased hepatotoxicity risk |
| Tetracyclines | Minor | Decreased tetracycline absorption |
| Chlorpromazine | Minor | Increased risk of extrapyramidal symptoms |
๐จ Major Interactions
- Amiodarone
- Cimetidine
- Cyclosporine
- Digoxin
- Mefloquine
- Penicillamine
- Tamoxifen
โก Moderate Interactions
- Antacids
- Kaolin
- Magnesium trisilicate
- Corticosteroids
- Insulin
- Antidiabetic agents
โน๏ธ Minor Interactions
- Alcohol
- Tetracyclines
- Chlorpromazine
๐ฝ๏ธ Food Interactions
Food may increase absorption; avoid grapefruit juice.
๐ท Alcohol Interaction
May increase risk of hepatotoxicity; avoid excessive alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to chloroquine or 4-aminoquinolines; retinal or visual field changes; porphyria; myasthenia gravis; G6PD deficiency (caution).
๐ Monitoring Parameters
Complete blood count, liver function tests, renal function, ophthalmologic exam (baseline and periodic), ECG (if risk factors).
๐คฑ Lactation Safety
Excreted in breast milk; caution advised.
๐ Overdose Management
Immediate gastric lavage; activated charcoal; supportive care; monitor for cardiac arrhythmias, seizures, and hypotension.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for coec 250mg tablet
View AllAlternative brands with exact same active ingredient (Chloroquine (250mg)):
-
zolar 250mg tabletPan Pharmaceuticals Ltd โน3.00 40% CHEAPER
-
malaquin 250mg tabletPCI Pharmaceuticals โน3.98 20.4% CHEAPER
-
malgo 250mg tabletSuzikem Drugs Pvt Ltd โน4.00 20% CHEAPER
-
Troyquin 250mg TabletTroikaa Pharmaceuticals Ltd โน4.76 4.8% CHEAPER
-
ceequine 250mg tabletPCI Pharmaceuticals โน4.85 3% CHEAPER
-
anaquin 250mg tabletNatco Pharma Ltd โน5.60 12% COSTLIER
-
melubrin 250mg tabletSun Pharmaceutical Industries Ltd โน5.78 15.6% COSTLIER
-
mahaquin 250mg tabletMankind Pharma Ltd โน5.88 17.6% COSTLIER
-
malacure 250mg tabletPatson Laboratories Pvt Ltd โน5.96 19.2% COSTLIER
-
larbin 250mg tabletEden Healthcare Pvt Ltd โน6.00 20% COSTLIER
Medical Note: Always consult your doctor before switching medications.