codistar-dx cough syrup - Uses, Price, Side Effects & Substitutes
What is codistar-dx cough syrup used for?
Alex Junior Syrup (Chlorpheniramine Maleate + Dextromethorphan Hydrobromide) is used to treat RESPIRATORY. It contains Chlorpheniramine Maleate (4mg/5ml) + Dextromethorphan Hydrobromide (10mg/5ml), which Chlorpheniramine: H1-receptor antagonist; Dextromethorphan: NMDA receptor antago. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlorpheniramine Maleate + Dextromethorphan Hydrobromide
- Manufacturer: Mankind Pharma Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ codistar-dx cough syrup Uses & Benefits
๐ Drug Information
| Generic Name(s) | Chlorpheniramine Maleate + Dextromethorphan Hydrobromide |
| Brand Name | Alex Junior Syrup |
| Manufacturer | Mankind Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Antitussive |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Chlorpheniramine: H1-receptor antagonist; Dextromethorphan: NMDA receptor antagonist and sigma-1 agonist
Mechanism Steps
๐ก How to Take codistar-dx cough syrup
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of codistar-dx cough syrup
โ Common Side Effects
- Drowsiness
- Dry mouth
- Dizziness
- Nausea
๐จ Serious Side Effects
- Respiratory depression
- Serotonin syndrome
- Seizures
- QT prolongation
โ ๏ธ Rare Side Effects
- Hypotension
- Allergic reactions
- Urinary retention
- Blurred vision
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis, serotonin syndrome |
| CYP2D6 inhibitors | Major | Increased dextromethorphan levels, toxicity |
| CNS depressants | Major | Additive sedation, respiratory depression |
| Anticholinergics | Moderate | Additive anticholinergic effects |
| SSRIs | Moderate | Serotonin syndrome risk |
| Alcohol | Minor | Increased sedation |
๐จ Major Interactions
- MAOIs
- CYP2D6 inhibitors
- CNS depressants
โก Moderate Interactions
- Anticholinergics
- SSRIs
- SNRIs
โน๏ธ Minor Interactions
- Alcohol
- Caffeine
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase dextromethorphan levels
๐ท Alcohol Interaction
Increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, MAOI use within 14 days, asthma attack, severe hypertension
๐ Monitoring Parameters
CNS depression, respiratory rate, blood pressure, heart rate
๐คฑ Lactation Safety
Use with caution; may pass into breast milk
๐ Overdose Management
Gastric lavage, activated charcoal, supportive care; naloxone may reverse dextromethorphan effects
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double