clygan eye ointment - Ganciclovir (1.5mg) medicine

clygan eye ointment

4.6 (13 reviews)
๐Ÿญ Indoco Remedies Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 23, 2026

What is clygan eye ointment used for?

Clovir Eye Gel (Ganciclovir) is used to treat OPHTHAL. It contains Ganciclovir (1.5mg), which Inhibits viral DNA synthesis by competitive inhibition of viral DNA polymerase a. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ganciclovir
  • Manufacturer: Indoco Remedies Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š clygan eye ointment Uses & Benefits

Treatment of acute herpetic keratitis (dendritic ulcers)

Off-label uses: Herpes zoster ophthalmicus, Cytomegalovirus (CMV) retinitis (systemic)

๐Ÿ“‹ Drug Information

Generic Name(s)Ganciclovir
Brand NameClovir Eye Gel
ManufacturerIndoco Remedies Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassAntiviral (Non-HIV) drugs
Route of AdministrationOphthalmic (topical)
StorageStore at 15-25ยฐC; do not freeze
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption after ocular administration
DistributionDistributes into ocular tissues; systemic distribution minimal
Protein Binding1-2%
MetabolismNot significantly metabolized in the eye; systemic metabolism via hepatic glucuronidation
Half-Life3-4 hours (systemic)
ExcretionRenal (primarily unchanged drug)
BioavailabilityLow systemic bioavailability due to topical application
Onset of ActionNot specified; clinical improvement typically within days
Peak Plasma TimeNot applicable for topical ocular use
Duration of ActionNot specified; dosing every 4-6 hours

How It Works

Inhibits viral DNA synthesis by competitive inhibition of viral DNA polymerase and incorporation into viral DNA

Mechanism Steps

1Ganciclovir is phosphorylated to ganciclovir monophosphate by viral thymidine kinase (HSV/VZV) or UL97 kinase (CMV)
2Cellular kinases convert to ganciclovir triphosphate (active form)
3Ganciclovir triphosphate competitively inhibits viral DNA polymerase

๐Ÿ’ก How to Take clygan eye ointment

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clygan eye ointment

โœ… Common Side Effects

  • Blurred vision
  • Eye irritation
  • Conjunctival hyperemia
  • Punctate keratitis

๐Ÿšจ Serious Side Effects

  • Corneal edema
  • Optic neuritis
  • Retinal detachment

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Angioedema

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Mycophenolate mofetil Major Increased risk of myelosuppression
Zidovudine Major Increased risk of neutropenia and anemia
Probenecid Major Reduced renal clearance of ganciclovir
Cytotoxic agents Moderate Additive myelosuppression
Immunosuppressants Moderate Increased risk of infection
Didanosine Minor Possible increased didanosine levels

๐Ÿšจ Major Interactions

  • Mycophenolate mofetil
  • Zidovudine
  • Probenecid

โšก Moderate Interactions

  • Cytotoxic agents
  • Immunosuppressants

โ„น๏ธ Minor Interactions

  • Didanosine

๐Ÿฝ๏ธ Food Interactions

None known for topical use

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ganciclovir or acyclovir

๐Ÿ“Š Monitoring Parameters

Ophthalmic examination for corneal healing; visual acuity

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

No specific antidote; supportive care; unlikely with topical use

โฐ Missed Dose

Apply as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for clygan eye ointment

View All

Alternative brands with exact same active ingredient (Ganciclovir (1.5mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

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