clozole v6 tablet
What is clozole v6 tablet used for?
AF 150 Tablet DT (Fluconazole) is used to treat ANTI INFECTIVES. It contains Fluconazole (NA), which Inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing conversion of lanos. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fluconazole
- Manufacturer: Psycormedies
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ clozole v6 tablet Uses & Benefits
Vaginal candidiasis, oropharyngeal candidiasis, esophageal candidiasis, systemic candidiasis, cryptococcal meningitis, prophylaxis in immunocompromised patients
Off-label uses: Coccidioidomycosis, histoplasmosis, blastomycosis, dermatophytosis, onychomycosis
๐ Drug Information
| Generic Name(s) | Fluconazole |
| Brand Name | AF 150 Tablet DT |
| Manufacturer | Psycormedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fungal ergosterol synthesis inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing conversion of lanosterol to ergosterol, disrupting fungal cell membrane synthesis
Mechanism Steps
๐ก How to Take clozole v6 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of clozole v6 tablet
โ Common Side Effects
- Headache
- Nausea
- Abdominal pain
- Diarrhea
- Dizziness
- Rash
๐จ Serious Side Effects
- Hepatotoxicity
- QT prolongation
- Torsades de pointes
- Stevens-Johnson syndrome
- Anaphylaxis
- Exfoliative dermatitis
โ ๏ธ Rare Side Effects
- Alopecia
- Seizures
- Thrombocytopenia
- Leukopenia
- Agranulocytosis
- Hypertriglyceridemia
- Hypokalemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Phenytoin | Major | Increased phenytoin levels, toxicity |
| Sulfonylureas | Major | Hypoglycemia |
| Cisapride | Major | QT prolongation, arrhythmias |
| Terfenadine | Major | QT prolongation, arrhythmias |
| Astemizole | Major | QT prolongation, arrhythmias |
| Rifampin | Major | Decreased fluconazole efficacy |
| Rifabutin | Major | Increased rifabutin levels, uveitis |
| Tacrolimus | Major | Increased tacrolimus levels, nephrotoxicity |
| Sirolimus | Major | Increased sirolimus levels |
| Alfentanil | Major | Increased alfentanil levels, respiratory depression |
| Midazolam | Major | Increased midazolam levels, sedation |
| Triazolam | Major | Increased triazolam levels, sedation |
| Nifedipine | Major | Increased nifedipine levels, hypotension |
| Verapamil | Major | Increased verapamil levels, bradycardia |
| Atorvastatin | Major | Increased statin levels, myopathy |
| Simvastatin | Major | Increased statin levels, myopathy |
| Losartan | Major | Decreased losartan efficacy |
| Methadone | Major | Increased methadone levels, QT prolongation |
| Celecoxib | Major | Increased celecoxib levels |
| Flurbiprofen | Major | Increased flurbiprofen levels |
| Naproxen | Major | Increased naproxen levels |
| Ibuprofen | Major | Increased ibuprofen levels |
| Oral contraceptives | Major | Decreased contraceptive efficacy |
| Pimozide | Major | QT prolongation, arrhythmias |
| Quinidine | Major | QT prolongation, arrhythmias |
| Tolbutamide | Major | Hypoglycemia |
| Zidovudine | Major | Increased zidovudine levels |
| Cyclosporine | Moderate | Increased cyclosporine levels |
| Theophylline | Moderate | Increased theophylline levels, toxicity |
| Hydrochlorothiazide | Moderate | Increased fluconazole levels |
| Cimetidine | Minor | Decreased fluconazole absorption |
| Antacids | Minor | Decreased fluconazole absorption |
| Sucralfate | Minor | Decreased fluconazole absorption |
| Didanosine | Minor | Decreased fluconazole absorption |
| Ritonavir | Minor | Increased fluconazole levels |
| Saquinavir | Minor | Increased saquinavir levels |
๐จ Major Interactions
- Warfarin
- Phenytoin
- Sulfonylureas
- Cisapride
- Terfenadine
- Astemizole
- Rifampin
- Rifabutin
- Tacrolimus
- Sirolimus
- Alfentanil
- Benzodiazepines (midazolam, triazolam)
- Calcium channel blockers (nifedipine, verapamil)
- HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
- Losartan
- Methadone
- NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
- Oral contraceptives
- Pimozide
- Quinidine
- Tolbutamide
- Warfarin
- Zidovudine
โก Moderate Interactions
- Cyclosporine
- Theophylline
- Hydrochlorothiazide
- Phenytoin
- Rifampin
- Rifabutin
- Tacrolimus
- Sirolimus
- Alfentanil
- Benzodiazepines (midazolam, triazolam)
- Calcium channel blockers (nifedipine, verapamil)
- HMG-CoA reductase inhibitors (atorvastatin, simvastatin)
- Losartan
- Methadone
- NSAIDs (celecoxib, flurbiprofen, naproxen, ibuprofen)
- Oral contraceptives
- Pimozide
- Quinidine
- Tolbutamide
- Warfarin
- Zidovudine
โน๏ธ Minor Interactions
- Cimetidine
- Antacids
- Sucralfate
- Didanosine
- Ritonavir
- Saquinavir
- Zidovudine
๐ฝ๏ธ Food Interactions
No significant food interactions; absorption not affected by food
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to fluconazole or azoles; concomitant use with terfenadine, astemizole, cisapride, pimozide, quinidine
๐ Monitoring Parameters
Liver function tests, renal function, signs of hepatotoxicity, QT interval if risk factors
๐คฑ Lactation Safety
Excreted in breast milk; use with caution
๐ Overdose Management
Symptomatic and supportive; hemodialysis may enhance elimination
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for clozole v6 tablet
View AllAlternative brands with exact same active ingredient (Fluconazole (NA)):
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fluzen capsuleJaywin Remedies Pvt Ltd โน2.26 85.6% CHEAPER
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cona tabletMonokem Labs โน10.83 31.2% CHEAPER
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Fungonil TabletMars Therapeutics & Chemicals Ltd โน11.58 26.4% CHEAPER
-
flucol p tabletSKN Organics โน11.73 25.4% CHEAPER
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monila f tabletMagnachem Pharmaceuticals Pvt Ltd โน14.06 10.6% CHEAPER
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Fuspin TabletCerspin Healthcare Pvt Ltd โน15.94 1.3% COSTLIER
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Flumit TabletAdmit Pharmaceuticals Pvt Ltd โน16.69 6.1% COSTLIER
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Fluconij TabletSunij Pharma Pvt Ltd โน17.47 11.1% COSTLIER
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fungicare creamWin-Medicare Pvt Ltd โน19.69 25.2% COSTLIER
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alucon tabletAnvik Biotech โน19.86 26.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.