clozmet 0.25mg tablet md - Clonazepam (0.25mg) medicine

clozmet 0.25mg tablet md - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Emocare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is clozmet 0.25mg tablet md used for?

Anxipam (Clonazepam) is used to treat NEURO CNS. It contains Clonazepam (0.25mg), which Enhances GABA-mediated inhibition by binding to benzodiazepine site on GABA-A re. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clonazepam
  • Manufacturer: Emocare
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š clozmet 0.25mg tablet md Uses & Benefits

Panic disorder, seizure disorders (e.g., Lennox-Gastaut syndrome, myoclonic seizures), anxiety disorders, REM sleep behavior disorder.

Off-label uses: Bipolar disorder (mania), restless legs syndrome, tinnitus, stiff-person syndrome.

๐Ÿ“‹ Drug Information

Generic Name(s)Clonazepam
Brand NameAnxipam
ManufacturerEmocare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepines
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; peak plasma concentrations achieved within 1-4 hours.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.
Protein BindingApproximately 85% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP3A4 to inactive metabolites (mainly 7-aminoclonazepam).
Half-Life30-40 hours
ExcretionPrimarily renal excretion of metabolites; less than 2% excreted unchanged.
Bioavailability90%
Onset of Action30-60 minutes
Peak Plasma Time1-4 hours
Duration of Action6-12 hours (for single dose); longer with repeated dosing due to accumulation.

How It Works

Enhances GABA-mediated inhibition by binding to benzodiazepine site on GABA-A receptors, increasing chloride ion conductance.

Mechanism Steps

1Binds to benzodiazepine site on GABA-A receptor
2Increases affinity of GABA for the receptor
3Enhances chloride ion channel opening frequency

๐Ÿ’ก How to Take clozmet 0.25mg tablet md

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clozmet 0.25mg tablet md

โœ… Common Side Effects

  • Drowsiness
  • dizziness
  • ataxia
  • fatigue
  • somnolence
  • coordination impairment

๐Ÿšจ Serious Side Effects

  • Respiratory depression
  • paradoxical reactions (agitation, aggression)
  • dependence
  • withdrawal seizures
  • suicidal ideation

โš ๏ธ Rare Side Effects

  • Blood dyscrasias (thrombocytopenia)
  • hepatic dysfunction
  • hypersensitivity reactions
  • SIADH

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Major Enhanced sedation and respiratory depression
Opioids Major Additive CNS depression, risk of respiratory depression
Ketoconazole Major Increased clonazepam levels due to CYP3A4 inhibition
Carbamazepine Moderate Decreased clonazepam levels due to CYP3A4 induction
Valproate Moderate Possible increased risk of absence seizures
Grapefruit juice Minor May increase clonazepam levels

๐Ÿšจ Major Interactions

  • CNS depressants (e.g., alcohol, opioids, barbiturates)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

โšก Moderate Interactions

  • CYP3A4 inducers (e.g., carbamazepine, phenytoin)
  • Valproate

โ„น๏ธ Minor Interactions

  • Oral contraceptives
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase levels; avoid concurrent use.

๐Ÿท Alcohol Interaction

Additive CNS depression; avoid alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to benzodiazepines, severe hepatic impairment, narrow-angle glaucoma, respiratory insufficiency, myasthenia gravis.

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, CBC, mental status, respiratory rate, signs of dependence/withdrawal.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid breastfeeding or use with caution.

๐Ÿ’Š Overdose Management

Supportive care; flumazenil as antidote (use with caution due to risk of seizures).

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for clozmet 0.25mg tablet md

View All

Alternative brands with exact same active ingredient (Clonazepam (0.25mg)):

Medical Note: Always consult your doctor before switching medications.

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