Dilona 25mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is clovin 25mg injection used for?
This medicine is a diclofenac sodium injection used for rapid relief of moderate to severe pain and inflammation. It works by blocking COX enzymes and is given by a healthcare professional.
- Generic Name: Diclofenac
- Manufacturer: Vindas Chemical Industry Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clovin 25mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा डाइक्लोफेनाक सोडियम का इंजेक्शन है, जिसका उपयोग मध्यम से गंभीर दर्द और सूजन को जल्दी कम करने के लिए किया जाता है। यह आमतौर पर ऑपरेशन के बाद के दर्द, गुर्दे की पथरी के दर्द, गठिया के दर्द, और चोट लगने पर होने वाले दर्द के लिए दी जाती है। यह दवा सूजन पैदा करने वाले रसायनों को रोककर काम करती है। यह इंजेक्शन डॉक्टर या नर्स द्वारा ही लगाया जाता है, इसे खुद नहीं लगाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में असहजता, सिरदर्द, चक्कर आना और इंजेक्शन लगाने की जगह पर दर्द या लालिमा शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, दिल का दौरा, स्ट्रोक, गुर्दे की समस्या, गंभीर एलर्जी और लीवर की क्षति शामिल हो सकती है। अगर आपको काला मल, खून की उल्टी, सीने में दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा ही लगाई जानी चाहिए। इसे खुद न लगाएं। अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर अगर आपको पेट के अल्सर, दिल की बीमारी, गुर्दे या लीवर की समस्या, या अस्थमा है। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। इस दवा के साथ शराब न पिएं। बिना डॉक्टर की सलाह के इस दवा का इस्तेमाल लंबे समय तक न करें।
💊 clovin 25mg injection Uses & Benefits
[{"condition":"Acute postoperative pain","description":"Provides rapid relief of moderate to severe pain following surgical procedures.","evidence":"Well-established"},{"condition":"Renal colic","description":"Effective in relieving the severe pain associated with kidney stones.","evidence":"Well-established"},{"condition":"Acute exacerbation of osteoarthritis","description":"Reduces pain and inflammation during flare-ups of osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis flare","description":"Helps control pain and swelling in acute rheumatoid arthritis attacks.","evidence":"Well-established"},{"condition":"Acute musculoskeletal injuries","description":"Used for pain relief in conditions such as sprains, strains, and fractures.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine headache","description":"Sometimes used off-label for acute migraine attacks when other treatments fail.","evidence":"Limited"},{"condition":"Biliary colic","description":"May be used off-label for pain relief in gallbladder attacks.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Renal colic, Postoperative pain, Musculoskeletal injuries
📋 Drug Information
| Generic Name(s) | Diclofenac |
| Brand Name | Adiflam 50mg Tablet |
| Manufacturer | Vindas Chemical Industry Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Intramuscular or intravenous injection. The intramuscular injection is usually given deep into the gluteal muscle. Intravenous administration should be given slowly over 2-5 minutes to reduce the risk of adverse effects |
| Storage | Store below 25°C (77°F). Protect from light. Do not freeze. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Diclofenac sodium is a nonsteroidal anti-inflammatory drug that exerts its analgesic, antipyretic, and anti-inflammatory effects primarily through inhibition of cyclooxygenase (COX) enzymes. It inhibits both COX-1 and COX-2, although it may have a slightly higher affinity for COX-2. This inhibition leads to a decrease in the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. The reduction in prostaglandin levels in peripheral tissues reduces pain and swelling, while its action in the central nervous system contributes to its analgesic and antipyretic effects.
Mechanism Steps
💡 How to Take clovin 25mg injection
Strength: Injection: 25 mg/mL (as diclofenac sodium).
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 25 mg to 75 mg given by intramuscular injection once or twice daily, depending on the severity of pain and the patient's response. The maximum daily dose is 150 mg. For intravenous use, 25 mg to 75 mg may be given slowly over 2-5 minutes, and the dose may be repeated after 4-6 hours if needed. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) are at increased risk of NSAID-related adverse effects, especially gastrointestinal bleeding and renal impairment. The lowest effective dose should be used for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | In patients with mild to moderate renal impairment (eGFR 30-89 mL/min), no dose adjustment is usually necessary, but caution is advised. In severe renal impairment (eGFR <30 mL/min), diclofenac is contraindicated. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is usually necessary, but caution is advised. In severe hepatic impairment, diclofenac is contraindicated. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 150 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clovin 25mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| Cyclosporine | Major | |
| Diuretics | Major | |
| ACE inhibitors | Major | |
| SSRIs | Major |
🚨 Major Interactions
- Warfarin
- Aspirin
- Other NSAIDs
- Corticosteroids
- Methotrexate
- Lithium
- Cyclosporine
- Diuretics
- ACE inhibitors
- Selective serotonin reuptake inhibitors (SSRIs)
⚡ Moderate Interactions
- Beta-blockers
- Angiotensin receptor blockers (ARBs)
- Digoxin
- Phenytoin
- Rifampicin
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine because it can increase the risk of gastrointestinal bleeding and may worsen liver toxicity. Patients should be advised not to consume alcohol during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to diclofenac or other NSAIDs","Active peptic ulcer disease or history of recurrent ulcers","Severe heart failure","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Cardiovascular risk: NSAIDs increase the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke. Use the lowest effective dose for the shortest duration.","Gastrointestinal risk: NSAIDs increase the risk of serious gastrointestinal adverse events, including bleeding, ulceration, and perforation. Use with caution in patients with a history of ulcer disease.","Renal risk: NSAIDs can cause renal impairment, especially in patients with pre-existing kidney disease, heart failure, or volume depletion.","Hepatic risk: Diclofenac can cause hepatotoxicity. Monitor liver enzymes in patients on long-term therapy.","Hypersensitivity: Serious allergic reactions, including anaphylaxis, can occur. Discontinue if any allergic reaction occurs.","Skin reactions: Serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported. Discontinue at the first sign of rash.","Hematologic effects: Diclofenac can inhibit platelet aggregation and prolong bleeding time. Use with caution in patients with bleeding disorders.","Use in elderly: Elderly patients are at higher risk of NSAID-related adverse effects. Use with caution and monitor closely."]
🤱 Lactation Safety
Diclofenac is excreted in breast milk in small amounts. The American Academy of Pediatrics considers it compatible with breastfeeding, but it is recommended to use the lowest effective dose for the shortest duration. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of diclofenac can cause symptoms such as nausea, vomiting, abdominal pain, gastrointestinal bleeding, headache, dizziness, and in severe cases, acute renal failure, liver damage, and seizures. Management includes supportive care, gastric lavage if within 1-2 hours of ingestion, activated charcoal, and monitoring of vital signs and renal and hepatic function. There is no specific antidote. Hemodialysis is not effective in removing diclofenac due to high protein binding.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, it should be given as soon as possible if within a few hours of the scheduled time. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose to catch up.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a clinical setting. Do not attempt to self-administer. Inform your doctor about all your medical conditions, especially if you have a history of stomach ulcers, heart disease, kidney or liver problems, or asthma. Tell your doctor about all other medicines you are taking, including blood thinners, steroids, antidepressants, and diuretics. Avoid alcohol while receiving this medicine as it increases the risk of stomach bleeding. Do not use this medicine for more than the recommended duration without medical advice. If you experience any signs of an allergic reaction, severe abdominal pain, or unusual bleeding, seek immediate medical attention.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of NSAID-related side effects, including gastrointestinal bleeding, renal impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. NSAIDs may affect ovulation and are not recommended during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine is often used for postoperative pain. It should be used with caution in patients recovering from surgery, especially those with cardiovascular or renal risk factors. It is contraindicated for perioperative pain in coronary artery bypass graft surgery.
🦷 Dental Procedures
This medicine can be used for pain relief after dental procedures. However, it may increase bleeding risk during dental surgery. Inform your dentist if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous activities that could increase the risk of bleeding or injury. If you experience dizziness or fatigue, avoid driving or operating heavy machinery. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some patients. Avoid driving or operating machinery until you know how it affects you. It is usually given in a clinical setting, so it may require a visit to a healthcare facility, which could impact your work schedule. Discuss with your employer if you need time off for treatment.
🛑 When to Stop This Medicine
This medicine is intended for short-term use. Stop using it when your pain is controlled or as directed by your doctor. Do not stop suddenly if you have been on long-term therapy without consulting your doctor, as this may cause rebound pain. If you experience any serious side effects, stop the medicine and seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the increased risk of serious cardiovascular events, gastrointestinal bleeding, and renal impairment. If long-term therapy is necessary, regular monitoring of renal and hepatic function, blood pressure, and complete blood count is required. Patients should be reviewed periodically to assess the need for continued treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay help reduce pain in some patients.
Evidence: ModerateAlternative for localized pain with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor, as NSAIDs may affect immune response in rare cases.
📦 Storage Guide
✅ DO
Store below 25°C (77°F)
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not expose to direct sunlight
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep out of reach of children
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of the prescription. Since it is an injection, it should be stored below 25°C and protected from light. If traveling by air, keep it in your carry-on luggage with proper documentation. For international travel, check the customs regulations of your destination country regarding injectable medications. It is advisable to carry a doctor's letter explaining the need for this medicine.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts relieving pain within 10 to 30 minutes after injection, with peak effects in about 30 minutes to 2 hours.
A: The analgesic effect typically lasts 4 to 6 hours, but this can vary depending on the dose and individual factors.
A: This medicine can affect kidney function, especially in patients with pre-existing kidney disease. Your doctor will monitor your kidney function during treatment.
A: This medicine should be avoided in the third trimester of pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.
A: You should not take this medicine with other NSAIDs or aspirin without consulting your doctor, as it may increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for clovin 25mg injection
View AllAlternative brands with exact same active ingredient:
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diclogen injectionAGIO Pharmaceuticals Ltd ₹2.27 89% CHEAPER
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diclofam 25mg injectionIntas Pharmaceuticals Ltd ₹2.28 89% CHEAPER
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glygesic 25mg injectionTorque Pharmaceuticals Pvt Ltd ₹2.37 88.6% CHEAPER
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diconil 25mg injectionJarson Pharmaceuticals ₹3.50 83.1% CHEAPER
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Runac 25mg InjectionSun Pharmaceutical Industries Ltd ₹3.50 83.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: This medicine is an injection and must be given by a healthcare professional in a clinical setting. - Myth: This medicine is safe for long-term use.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects. - Myth: This medicine can be taken with alcohol.
Fact: Alcohol should be avoided as it increases the risk of gastrointestinal bleeding.
🔄 Alternative Options
Generic Alternatives
- Diclofenac sodium injection 25 mg/mL
Brand Alternatives
- Voveran 25mg injection
- Dynapar 25mg injection
- Dicloran 25mg injection