CCQ 25 Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden blurring of vision, flashing lights, or loss of part of your visual field
- Severe pelvic or abdominal pain with bloating
- Rapid weight gain over a few days
- Shortness of breath or difficulty breathing
- Yellowing of the skin or eyes, or dark urine
- Severe allergic reaction with facial swelling or throat tightness
- Heavy vaginal bleeding or passage of large clots
If experiencing severe symptoms, call emergency services immediately.
What is clomova 25mg/50mg tablet used for?
This medicine is an oral fertility tablet that combines clomiphene 25 mg, which helps trigger ovulation, with coenzyme Q10 50 mg, an antioxidant that may support egg and sperm quality. It is taken under specialist supervision, usually for a few days early in the menstrual cycle, and it is not meant for use during pregnancy.
- Generic Name: Clomiphene + Coenzyme Q10
- Manufacturer: Zogenix Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clomova 25mg/50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से महिलाओं में ओव्यूलेशन यानी अंडोत्सर्जन को बढ़ाने के लिए दी जाती है, खासकर उन महिलाओं में जिनके मासिक चक्र अनियमित हैं या अंडे नहीं बनते। इसमें क्लोमिफीन और कोएंजाइम क्यू10 दोनों होते हैं। क्लोमिफीन दिमाग से निकलने वाले हार्मोन को बढ़ाकर अंडाशय को उत्तेजित करता है, जिससे अंडा बनता और निकलता है। कोएंजाइम क्यू10 एक एंटीऑक्सिडेंट है जो अंडे और शुक्राणु की गुणवत्ता में सहायता कर सकता है। यह दवा कभी-कभी पुरुषों में शुक्राणु की संख्या और गुणवत्ता सुधारने के लिए भी विशेषज्ञ की सलाह पर दी जाती है। यह दवा गर्भनिरोधक नहीं है और इसे बिना डॉक्टर की सलाह के नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गर्मी लगना, मूड में बदलाव, स्तनों में कोमलता, जी मिचलाना, सिरदर्द और धुंधली दृष्टि शामिल हैं। कुछ महिलाओं को पेट के निचले हिस्से में हल्का दर्द या भारीपन महसूस हो सकता है। कोएंजाइम क्यू10 से कभी-कभी पेट खराब, भूख कम लगना या नींद न आना हो सकता है। गंभीर लेकिन दुर्लभ समस्याओं में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम शामिल है, जिसमें अचानक वजन बढ़ना, पेट फूलना और सांस लेने में तकलीफ हो सकती है। दृष्टि में अचानक बदलाव, तेज पेट दर्द या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर द्वारा बताई गई मात्रा और दिनों में ही लें, अपने मन से मात्रा न बढ़ाएं। अगर आंखों की रोशनी में कोई बदलाव महसूस हो तो गाड़ी चलाना बंद कर दें और तुरंत डॉक्टर को बताएं। पेट में तेज दर्द, अचानक वजन बढ़ना या सांस लेने में तकलीफ होने पर तुरंत अस्पताल जाएं, क्योंकि यह ओवेरियन हाइपरस्टिमुलेशन का संकेत हो सकता है। अगर गर्भावस्था की संभावना हो तो दवा शुरू करने से पहले डॉक्टर को बताएं। नियमित अल्ट्रासाउंड और खून की जांच कराते रहें। दवा को ठंडी, सूखी जगह पर रखें और बच्चों की पहुंच से दूर रखें।
💊 clomova 25mg/50mg tablet Uses & Benefits
- [{"condition":"Ovulation induction in anovulatory infertility","description":"This medicine is used to stimulate the release of an egg in women whose cycles are irregular or absent because of problems with ovulation.","evidence":"Well-established"},{"condition":"Unexplained infertility","description":"Sometimes prescribed to increase the number of eggs released per cycle in couples with unexplained infertility, often alongside timed intercourse or intrauterine insemination.","evidence":"Moderate"},{"condition":"Male subfertility with abnormal semen parameters","description":"Clomiphene has been used in selected men to raise gonadotropin levels, and coenzyme Q10 is added for its antioxidant effect on sperm.
- Evidence for the combination is limited.","evidence":"Limited"},{"condition":"Antioxidant support during assisted reproduction","description":"Coenzyme Q10 is included in some fertility protocols with the aim of improving oocyte and embryo quality, although results across studies are not consistent.","evidence":"Limited"}]
Off-label uses: [{"condition":"Luteal phase support in selected cycles","description":"Occasionally used by specialists in selected ovulation induction protocols, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Idiopathic oligospermia","description":"Clomiphene has been tried in men with low sperm counts, but response is variable and it is not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Anovulatory infertility
Also treats: Polycystic ovary syndrome, Unexplained infertility, Male subfertility
📋 Drug Information
| Generic Name(s) | Clomiphene + Coenzyme Q10 |
| Brand Name | CCQ 100 Tablet |
| Manufacturer | Zogenix Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Ovulation stimulant / Antioxidant |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in its original packaging. Protect it from moisture, heat, and direct sunlight. Do not refrigerate unless the label specifically instructs you to do so. |
| Shelf Life | The shelf life is usually 24 months from the date of manufacture, but you should always check the expiry date printed on the pack. Do not use the tablets after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Clomiphene works by blocking estrogen receptors in the hypothalamus and pituitary gland. Because the brain no longer senses normal estrogen feedback, it increases the release of gonadotropin-releasing hormone, which in turn raises follicle-stimulating hormone and luteinizing hormone. These hormones stimulate the ovaries to mature and release an egg. Coenzyme Q10 is a fat-soluble antioxidant that participates in mitochondrial electron transport and helps protect cells from oxidative stress. In the context of fertility, it is believed to support the energy needs of developing eggs and sperm and to reduce oxidative damage, although the exact contribution of the 50 mg dose in this combination is not fully established.
Mechanism Steps
💡 How to Take clomova 25mg/50mg tablet
Strength: Immediate-release oral tablet containing clomiphene 25 mg and coenzyme Q10 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken by mouth once daily, but the exact dose and the number of days it is taken depend on the indication, the response of the ovaries, and the treatment protocol. Some clinicians start with a lower dose and increase it in later cycles if ovulation does not occur. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never adjust the dose yourself, and always follow the schedule given by your fertility specialist. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is intended for use in adults of reproductive age. It is not normally prescribed for elderly patients, and there is no established dosing schedule for this age group. |
| Renal Impairment | There is limited information on the use of this medicine in people with kidney disease. If you have reduced kidney function, your clinician should assess the risks and benefits before prescribing it, and monitoring may be needed. |
| Hepatic Impairment | This medicine should be avoided in people with liver disease or unexplained abnormal liver tests. If it is considered essential, a specialist should supervise its use and monitor liver function closely. |
| Maximum Daily Dose | The maximum daily dose should not exceed the dose prescribed by your clinician. In fertility practice, clomiphene is usually given for a limited number of days per cycle, and the total dose per cycle is decided by the specialist. Do not take extra tablets to try to improve results. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clomova 25mg/50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Gonadotropins | Major | |
| Thyroid hormone | Moderate | |
| Antidiabetic medicines | Moderate | |
| Hormonal contraceptives | Moderate | |
| Paracetamol | Minor |
🚨 Major Interactions
- Other ovulation-inducing agents such as gonadotropins
- Warfarin
⚡ Moderate Interactions
- Thyroid hormone replacement
- Antidiabetic medicines
- Hormonal contraceptives
🍷 Alcohol Interaction
Alcohol is best avoided while taking this medicine. It can worsen mood swings and hot flushes, may stress the liver, and is generally discouraged during fertility treatment because it can reduce the chances of conception.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known pregnancy","Unexplained abnormal vaginal bleeding","Liver disease or unexplained liver function abnormalities","Hormone-sensitive cancers such as breast or endometrial cancer","Ovarian cysts not related to polycystic ovary syndrome","Known hypersensitivity to clomiphene or coenzyme Q10","Use of hormonal contraceptives during the treatment cycle"]
⚠️ Warnings & Precautions
["This medicine must only be used under specialist supervision with appropriate monitoring.","Visual symptoms such as blurring or flashing lights require immediate medical review.","Ovarian hyperstimulation syndrome can occur and may need urgent treatment.","Multiple pregnancy is a recognised risk of ovulation induction.","Do not use this medicine if you are already pregnant.","Inform your doctor about all other medicines and supplements you take.","Avoid driving or operating machinery if you experience visual changes.","Keep all follow-up appointments for scans and blood tests."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. Clomiphene may reduce milk production, and there is not enough information about the passage of coenzyme Q10 into breast milk to consider it safe. Discuss alternative options with your doctor if you are breastfeeding.
💊 Overdose Management
Overdose with this medicine may cause severe pelvic pain, marked ovarian enlargement, visual disturbances, nausea, and hot flushes. If an overdose is suspected, contact a poison control centre or go to the nearest emergency department immediately. Treatment is supportive, with close monitoring of ovarian size, fluid balance, and vision. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you miss several doses, contact your fertility clinic for advice, because the timing of ovulation induction is important.
Additional Safety Advice
Take this medicine exactly as prescribed by your fertility specialist, and do not increase the dose on your own. Because clomiphene can cause visual symptoms, avoid driving or operating heavy machinery at night or whenever your vision feels unclear. Report any pelvic pain, rapid weight gain, or breathing difficulty immediately, as these may be signs of ovarian hyperstimulation. Do not start this medicine if you think you may already be pregnant, and use a reliable barrier method until your clinician confirms that it is safe to try to conceive. Keep all follow-up appointments for ultrasound and hormone blood tests, because monitoring is essential for safe use. Tell your doctor about all other medicines, supplements, and herbal products you take, especially hormonal treatments. Store the tablets in their original pack, away from moisture and direct sunlight, and keep them out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for elderly patients. It is used in adults of reproductive age for fertility treatment, and there is no established role or dosing schedule for older adults.
🤰 Pregnancy Planning (TTC)
This medicine is used to help you conceive, but it should be stopped once pregnancy is confirmed. If you are planning pregnancy, take folic acid supplements as advised, avoid alcohol and smoking, and attend all monitoring appointments. Discuss any other medicines you take with your doctor before starting this treatment.
🏥 Post-Surgery Considerations
If you have recently had surgery, especially pelvic or abdominal surgery, tell your fertility specialist before starting this medicine. They will decide whether it is safe to begin treatment and whether any additional monitoring is needed.
🦷 Dental Procedures
There is no specific restriction on dental procedures while taking this medicine. However, inform your dentist about all medicines you take, and if you need sedation or surgery, mention your fertility treatment to the dental team.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe and helpful while taking this medicine. However, if you develop pelvic pain, abdominal bloating, or shortness of breath, stop exercising and seek medical advice, because these may be signs of ovarian hyperstimulation. Avoid very intense or high-impact workouts during the treatment cycle unless your doctor says it is fine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Most people can continue their usual work while taking this medicine. However, if you experience blurred vision, dizziness, or significant mood changes, avoid driving or operating heavy machinery until you feel normal. Fertility treatment can be emotionally demanding, so plan for time off for scans and blood tests, and consider talking to your employer if you need flexible hours.
🛑 When to Stop This Medicine
Stop this medicine and contact your doctor immediately if you experience visual changes, severe pelvic pain, rapid weight gain, or difficulty breathing. Also stop if you confirm that you are pregnant, unless your specialist advises otherwise. Do not stop or restart the medicine on your own between cycles; always discuss the plan with your fertility specialist.
📅 Long-Term Use Effects
Long-term use of clomiphene is generally limited to a small number of cycles because the risk of ovarian hyperstimulation and visual side effects increases with repeated use. There is no strong evidence that clomiphene causes cancer, but long-term safety data are limited. Coenzyme Q10 is generally well tolerated over months, but its long-term effects at this dose in fertility treatment are not fully established. Regular review with your specialist is important, and alternative treatments should be considered if pregnancy does not occur after several cycles.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral aromatase inhibitor that is also used for ovulation induction and may be preferred in some women with polycystic ovary syndrome.
Evidence: Well-establishedInjectable hormones used for controlled ovarian stimulation when oral agents are not effective.
Evidence: Well-establishedWeight loss, diet, and exercise can restore ovulation in some women with polycystic ovary syndrome.
Evidence: Well-establishedSome couples use these as complementary approaches, but evidence for improving pregnancy rates is limited.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. Routine vaccinations can be given as advised by your doctor. If you are planning pregnancy, discuss the timing of any live vaccines with your clinician, as some vaccines need to be given before conception.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless the label instructs you to
✅ DO
Keep the tablets in the original container
❌ DON'T
Do not transfer them to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Keep a copy of your prescription and a letter from your doctor if you are travelling internationally, because clomiphene is a prescription medicine. Store the tablets in hand luggage rather than checked baggage to avoid extreme temperatures. If you are crossing time zones, keep to your prescribed schedule as closely as possible and discuss any major changes with your fertility clinic. Do not pack the tablets in a hot car or in direct sunlight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ovulation usually occurs about five to ten days after the last dose in a cycle. Your doctor will confirm ovulation with ultrasound or a progesterone blood test.
A: Yes, ovulation induction can increase the chance of twins or more because more than one egg may be released. Your doctor will monitor you with ultrasound to assess this risk.
A: Stop the medicine, avoid driving, and contact your doctor immediately. Visual symptoms are uncommon but need urgent review.
A: Only if your specialist prescribes them together. Combining ovulation-inducing medicines can increase the risk of ovarian hyperstimulation and requires close monitoring.
🤔 Common Patient Concerns
🔄 Substitutes for clomova 25mg/50mg tablet
View AllAlternative brands with exact same active ingredient:
-
ccliya max tablet 25 mg/50 mgZydus Cadila ₹250.00 28.4% CHEAPER
-
clofin 25 tabletHBC Lifesciences Pvt Ltd ₹275.00 21.2% CHEAPER
-
fertilix 25mg/50mg tabletInnovcare Lifesciences Pvt Ltd ₹295.00 15.5% CHEAPER
-
clomipreg q 25mg/50mg tabletRemedial Healthcare ₹315.60 9.6% CHEAPER
-
fertolast tabletEvalin Healthcare ₹380.00 8.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: It improves the chance of ovulation and conception, but it does not guarantee pregnancy, and many other factors affect fertility. - Myth: This medicine is a general energy booster.
Fact: It is a fertility medicine, not a general tonic, and it should only be used under medical supervision. - Myth: More tablets mean a better chance of twins.
Fact: Taking more than prescribed increases the risk of ovarian hyperstimulation and other complications without improving safety.
🔄 Alternative Options
Generic Alternatives
- Clomiphene 25 mg tablet
- Coenzyme Q10 50 mg capsule