clobeled gm cream
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
What is clobeled gm cream used for?
This medicine contains Clobetasol (0.5% w/w) + Gentamicin (0.2% w/w) and is used to treat DERMA. Clobetasol: Anti-inflammatory via glucocorticoid receptor binding; Gentamicin: Bactericidal by bindi. Always consult your doctor before use.
- Generic Name: Clobetasol + Gentamicin
- Manufacturer: Universal Micro Sciences
- Form: Allopathy
- Pregnancy Category: Category C
- Prescription Required: Yes
💊 clobeled gm cream Uses & Benefits
Inflammatory dermatoses with secondary bacterial infection, e.g., eczema, psoriasis, contact dermatitis.
Off-label uses: Lichen planus, discoid lupus erythematosus.
📋 Drug Information
| Generic Name(s) | Clobetasol + Gentamicin |
| Brand Name | Cosvate-GM Cream |
| Manufacturer | Universal Micro Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | DERMA |
| Action Class | Corticosteroid + Antibiotic |
| Route of Administration | Topical |
| Storage | Store at 20-25°C; protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Clobetasol: Anti-inflammatory via glucocorticoid receptor binding; Gentamicin: Bactericidal by binding to 30S ribosomal subunit.
Mechanism Steps
💡 How to Take clobeled gm cream
Follow your doctor's prescription exactly.
⚠️ Side Effects of clobeled gm cream
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | Increased nephrotoxicity and ototoxicity risk |
| Neuromuscular blocking agents | Major | Enhanced neuromuscular blockade |
| Loop diuretics | Moderate | Increased ototoxicity risk |
| Amphotericin B | Moderate | Increased nephrotoxicity risk |
| Other topical corticosteroids | Minor | Additive local effects |
🚨 Major Interactions
- Aminoglycosides
- Neuromuscular blocking agents
⚡ Moderate Interactions
- Loop diuretics
- Amphotericin B
🍷 Alcohol Interaction
No known interaction.
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to components, untreated bacterial/fungal/viral infections, skin ulcers, rosacea, perioral dermatitis.
🤱 Lactation Safety
Use with caution; avoid application to breast area.
💊 Overdose Management
Topical overdose unlikely; discontinue use and treat symptomatically.
⏰ Missed Dose
Apply as soon as remembered; skip if near next dose.