clobact sc ointment - Clobetasol (0.05% w/w) + Salicylic Acid (3% w/w) medicine

clobact sc ointment

4.4 (12 reviews)
๐Ÿญ Cutis Dermacare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is clobact sc ointment used for?

Amwisal Ointment (Clobetasol + Salicylic Acid) is used to treat DERMA. It contains Clobetasol (0.05% w/w) + Salicylic Acid (3% w/w), which Clobetasol: Anti-inflammatory via phospholipase A2 inhibition; Salicylic Acid: K. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clobetasol + Salicylic Acid
  • Manufacturer: Cutis Dermacare
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š clobact sc ointment Uses & Benefits

Psoriasis, eczema, dermatitis, lichen planus, discoid lupus erythematosus.

Off-label uses: Alopecia areata, Vitiligo

๐Ÿ“‹ Drug Information

Generic Name(s)Clobetasol + Salicylic Acid
Brand NameAmwisal Ointment
ManufacturerCutis Dermacare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassCorticosteroid + Keratolytic
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption varies; enhanced by inflamed skin or occlusion.
DistributionDistributes locally; minimal systemic distribution.
Protein BindingClobetasol: 96-99% bound to plasma proteins.
MetabolismClobetasol: Hepatic via CYP3A4; Salicylic Acid: Hepatic conjugation.
Half-LifeClobetasol: ~2-3 hours; Salicylic Acid: 2-3 hours (dose-dependent).
ExcretionClobetasol: Renal and biliary; Salicylic Acid: Renal.
BioavailabilityMinimal systemic absorption with intact skin.
Onset of ActionWithin a few days of regular use.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionVaries; typically 12-24 hours.

How It Works

Clobetasol: Anti-inflammatory via phospholipase A2 inhibition; Salicylic Acid: Keratolytic by dissolving intercellular cement.

Mechanism Steps

1Clobetasol binds to glucocorticoid receptors in cytoplasm.
2Receptor-ligand complex translocates to nucleus.
3Inhibits phospholipase A2, reducing arachidonic acid release.

๐Ÿ’ก How to Take clobact sc ointment

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clobact sc ointment

โœ… Common Side Effects

  • Burning
  • itching
  • irritation
  • dryness
  • folliculitis

๐Ÿšจ Serious Side Effects

  • Skin atrophy
  • HPA axis suppression
  • Cushing's syndrome
  • allergic contact dermatitis

โš ๏ธ Rare Side Effects

  • Hypopigmentation
  • secondary infection
  • perioral dermatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to salicylic acid absorption
CYP3A4 inhibitors (e.g., ketoconazole) Major Increased systemic corticosteroid effects
NSAIDs Moderate Additive gastrointestinal irritation (if absorbed)
Aspirin Moderate Increased salicylate toxicity risk

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors
  • Anticoagulants

โšก Moderate Interactions

  • NSAIDs
  • Aspirin

โ„น๏ธ Minor Interactions

  • Topical anesthetics
  • Other corticosteroids

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, viral skin infections, fungal infections, untreated bacterial infections, rosacea, perioral dermatitis.

๐Ÿ“Š Monitoring Parameters

Skin atrophy, HPA axis suppression, local irritation.

๐Ÿคฑ Lactation Safety

Use with caution; avoid application to breast area.

๐Ÿ’Š Overdose Management

Discontinue use; symptomatic treatment for systemic effects.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

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