clo 0.25mg tablet md

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Clonazepam (0.25mg)

🏭 Prochem Turnkey Projects Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

11 min read

Reviewed by

SaathiMed Expert Panel | Sep 21, 2026

What is clo 0.25mg tablet md used for?

This medicine contains Clonazepam (0.25mg) and is used to treat NEURO CNS. Enhances GABA-mediated inhibition by binding to benzodiazepine site on GABA-A receptors, increasing . Always consult your doctor before use.

Generic Name: Clonazepam
Manufacturer: Prochem Turnkey Projects Pvt Ltd
Form: Allopathy
Pregnancy Category: Category A
Prescription Required: Yes

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💊 clo 0.25mg tablet md Uses & Benefits

Panic disorder, seizure disorders (e.g., Lennox-Gastaut syndrome, myoclonic seizures), anxiety disorders, REM sleep behavior disorder.

Off-label uses: Bipolar disorder (mania), restless legs syndrome, tinnitus, stiff-person syndrome.

📋 Drug Information

Generic Name(s)	Clonazepam
Brand Name	Anxipam
Manufacturer	Prochem Turnkey Projects Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Benzodiazepines
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed after oral administration; peak plasma concentrations achieved within 1-4 hours.

DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.

Protein BindingApproximately 85% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP3A4 to inactive metabolites (mainly 7-aminoclonazepam).

Half-Life30-40 hours

ExcretionPrimarily renal excretion of metabolites; less than 2% excreted unchanged.

Bioavailability90%

Onset of Action30-60 minutes

Peak Plasma Time1-4 hours

Duration of Action6-12 hours (for single dose); longer with repeated dosing due to accumulation.

How It Works

Enhances GABA-mediated inhibition by binding to benzodiazepine site on GABA-A receptors, increasing chloride ion conductance.

Mechanism Steps

1Binds to benzodiazepine site on GABA-A receptor

2Increases affinity of GABA for the receptor

3Enhances chloride ion channel opening frequency

4Increases chloride ion influx

5Hyperpolarizes the neuron

6Reduces neuronal excitability

💡 How to Take clo 0.25mg tablet md

Follow your doctor's prescription exactly.

⚠️ Side Effects of clo 0.25mg tablet md

✅ Common Side Effects

Drowsiness

dizziness

ataxia

fatigue

somnolence

coordination impairment

🚨 Serious Side Effects

Respiratory depression

paradoxical reactions (agitation, aggression)

dependence

withdrawal seizures

suicidal ideation

⚠️ Rare Side Effects

Blood dyscrasias (thrombocytopenia)

hepatic dysfunction

hypersensitivity reactions

SIADH

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
Alcohol	Major	Enhanced sedation and respiratory depression
Opioids	Major	Additive CNS depression, risk of respiratory depression
Ketoconazole	Major	Increased clonazepam levels due to CYP3A4 inhibition
Carbamazepine	Moderate	Decreased clonazepam levels due to CYP3A4 induction
Valproate	Moderate	Possible increased risk of absence seizures
Grapefruit juice	Minor	May increase clonazepam levels

🚨 Major Interactions

CNS depressants (e.g., alcohol, opioids, barbiturates)
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

CYP3A4 inducers (e.g., carbamazepine, phenytoin)
Valproate

🍷 Alcohol Interaction

Additive CNS depression; avoid alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to benzodiazepines, severe hepatic impairment, narrow-angle glaucoma, respiratory insufficiency, myasthenia gravis.

🤱 Lactation Safety

Excreted in breast milk; avoid breastfeeding or use with caution.

💊 Overdose Management

Supportive care; flumazenil as antidote (use with caution due to risk of seizures).

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

🔄 Substitutes for clo 0.25mg tablet md

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Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

clo 0.25mg tablet md

What is clo 0.25mg tablet md used for?

💊 clo 0.25mg tablet md Uses & Benefits

📋 Drug Information

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take clo 0.25mg tablet md

⚠️ Side Effects of clo 0.25mg tablet md

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

🔄 Substitutes for clo 0.25mg tablet md

😊 Was this information helpful?

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clo 0.25mg tablet md

What is clo 0.25mg tablet md used for?

💊 clo 0.25mg tablet md Uses & Benefits

📋 Drug Information

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take clo 0.25mg tablet md

⚠️ Side Effects of clo 0.25mg tablet md

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

🔄 Substitutes for clo 0.25mg tablet md

😊 Was this information helpful?

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