clindascan 300 capsule - Clindamycin (300mg) medicine

clindascan 300 capsule - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Medishri Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is clindascan 300 capsule used for?

Acnesol Gel (Clindamycin) is used to treat ANTI INFECTIVES. It contains Clindamycin (300mg), which Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit, preven. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Clindamycin
  • Manufacturer: Medishri Healthcare
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š clindascan 300 capsule Uses & Benefits

Treatment of acne vulgaris.

Off-label uses: Bacterial vaginosis (topical), Perioral dermatitis

๐Ÿ“‹ Drug Information

Generic Name(s)Clindamycin
Brand NameAcnesol Gel
ManufacturerMedishri Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassLincosamides
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionApproximately 10% of topically applied clindamycin is absorbed systemically.
DistributionDistributes widely into body tissues and fluids, including bone, but not significantly into cerebrospinal fluid.
Protein BindingAbout 93-94% bound to plasma proteins.
MetabolismHepatic metabolism to active and inactive metabolites.
Half-LifeApproximately 2-3 hours (topical absorption minimal).
ExcretionPrimarily renal (10% unchanged, rest as metabolites) and biliary.
BioavailabilityLow systemic bioavailability after topical application (<10%).
Onset of ActionWithin a few days to weeks of regular application.
Peak Plasma TimeNot applicable for topical use; minimal systemic absorption.
Duration of ActionSustained antibacterial effect on skin for up to 12 hours.

How It Works

Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit, preventing peptide bond formation.

Mechanism Steps

1Clindamycin binds to the 50S ribosomal subunit of bacteria.
2Inhibits peptide bond formation by blocking the peptidyl transferase activity.
3Prevents bacterial protein synthesis, leading to bacteriostatic effect.

๐Ÿ’ก How to Take clindascan 300 capsule

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clindascan 300 capsule

โœ… Common Side Effects

  • Skin dryness
  • Peeling
  • Itching
  • Erythema
  • Burning sensation

๐Ÿšจ Serious Side Effects

  • Pseudomembranous colitis
  • Severe allergic reactions
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Contact dermatitis
  • Urticaria
  • Angioedema

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Erythromycin Major Antagonism of antibacterial effect
Neuromuscular blocking agents Major Enhanced neuromuscular blockade
Warfarin Moderate Increased INR and bleeding risk
Oral contraceptives Moderate Reduced contraceptive efficacy
Kaolin Minor Reduced absorption of clindamycin
Aluminum-containing antacids Minor Reduced absorption of clindamycin

๐Ÿšจ Major Interactions

  • Erythromycin
  • Neuromuscular blocking agents

โšก Moderate Interactions

  • Warfarin
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Kaolin
  • Aluminum-containing antacids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to clindamycin or lincomycin; history of antibiotic-associated colitis.

๐Ÿ“Š Monitoring Parameters

Skin irritation, signs of superinfection, diarrhea.

๐Ÿคฑ Lactation Safety

Caution; not known if excreted in breast milk after topical use.

๐Ÿ’Š Overdose Management

Topical overdose unlikely; if ingested, symptomatic and supportive care.

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for clindascan 300 capsule

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Alternative brands with exact same active ingredient (Clindamycin (300mg)):

Medical Note: Always consult your doctor before switching medications.

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