Cledex-SF Oral Liquid: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of the face, lips, tongue, or throat
- Severe dizziness or fainting
- Fast, irregular, or pounding heartbeat
- Hallucinations or confusion
- Seizures
- Blood in vomit or stool
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is cledex -sf oral liquid used for?
This medicine is a combination of dextromethorphan (a cough suppressant) and guaifenesin (an expectorant) used to treat dry cough and chest congestion. It works by reducing the cough reflex and thinning mucus. The usual adult dose is 10 mL every 4 hours, not exceeding 60 mL in 24 hours.
- Generic Name: Dextromethorphan Hydrobromide + Guaifenesin
- Manufacturer: Panjon Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cledex -sf oral liquid के बारे में (Hindi Summary)
उपयोग: यह दवा सूखी खांसी और छाती में जकड़न के इलाज के लिए इस्तेमाल की जाती है। इसमें डेक्सट्रोमेथोर्फन और गुआइफेनेसिन दो सक्रिय तत्व होते हैं। डेक्सट्रोमेथोर्फन खांसी की प्रतिक्रिया को कम करता है और गुआइफेनेसिन बलगम को पतला करके बाहर निकालने में मदद करता है। यह दवा आमतौर पर सर्दी-जुकाम के कारण होने वाली खांसी के लिए दी जाती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, जी मिचलाना, उल्टी, पेट खराब होना और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, सांस लेने में कठिनाई, या मतिभ्रम शामिल हो सकते हैं। अगर आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इस दवा को लेते समय शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह दवा आप पर कैसा असर करती है। अगर खांसी 7 दिनों से अधिक समय तक बनी रहती है तो डॉक्टर से मिलें। बच्चों को 4 साल से कम उम्र में यह दवा न दें।
💊 cledex -sf oral liquid Uses & Benefits
[{"condition":"Dry cough","description":"Relieves dry, irritating cough by suppressing the cough reflex in the brain.","evidence":"Well-established"},{"condition":"Chest congestion","description":"Helps loosen mucus and phlegm in the airways, making it easier to cough out.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief of cough associated with the common cold.","evidence":"Well-established"},{"condition":"Inhaled irritants","description":"Soothes cough caused by inhaled irritants such as dust or smoke.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Cough
Also treats: Common cold, Chest congestion
📋 Drug Information
| Generic Name(s) | Dextromethorphan Hydrobromide + Guaifenesin |
| Brand Name | Alex Syrup |
| Manufacturer | Panjon Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antitussive and Expectorant Combination |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines a centrally acting cough suppressant and an expectorant. Dextromethorphan hydrobromide acts on the cough center in the medulla oblongata to raise the threshold for coughing, thereby reducing the frequency and intensity of the cough reflex. It is a non-opioid agent that does not cause respiratory depression or addiction at recommended doses. Guaifenesin increases the volume and reduces the viscosity of respiratory tract secretions by stimulating the secretory cells of the respiratory tract, which helps in the removal of mucus. Together, they provide symptomatic relief from cough and congestion.
Mechanism Steps
💡 How to Take cledex -sf oral liquid
Strength: Each 5 mL contains Dextromethorphan Hydrobromide 15 mg and Guaifenesin 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mL (2 teaspoons) every 4 hours as needed, not to exceed 6 doses (60 mL) in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Use a measuring cup or spoon to ensure accurate dosing. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 4 years of age. For children 4 to 12 years, consult a doctor for appropriate dosing. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult a doctor for appropriate dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with hepatic impairment. Consult a doctor for appropriate dosing. |
| Maximum Daily Dose | For adults: 60 mL in 24 hours. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cledex -sf oral liquid
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| SSRIs | Major | |
| CYP2D6 inhibitors | Major | |
| CNS depressants | Moderate | |
| Antihistamines | Moderate | |
| Alcohol | Moderate | |
| Grapefruit juice | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- MAO inhibitors (e.g., phenelzine, tranylcypromine)
- SSRIs (e.g., fluoxetine, sertraline)
- CYP2D6 inhibitors (e.g., quinidine, paroxetine)
⚡ Moderate Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Antihistamines (e.g., diphenhydramine)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and the risk of other side effects. It may also increase the risk of liver toxicity.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to dextromethorphan, guaifenesin, or any component of the formulation.","Concurrent use with MAO inhibitors or within 14 days of stopping MAO inhibitor therapy.","Chronic cough due to smoking, asthma, or emphysema.","Cough with excessive mucus (productive cough) unless directed by a doctor.","Children under 4 years of age."]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Avoid driving or operating machinery until you know how this medicine affects you.","Avoid alcohol while taking this medicine.","Consult a doctor if cough persists for more than 7 days, tends to recur, or is accompanied by fever, rash, or persistent headache.","Use with caution in patients with liver or kidney disease.","Use with caution in patients with asthma or chronic obstructive pulmonary disease.","Do not use to make a child sleepy.","Keep out of reach of children."]
🤱 Lactation Safety
Not established from the available information. Consult a doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, drowsiness, dizziness, hallucinations, agitation, rapid heart rate, and in severe cases, respiratory depression, seizures, and coma. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be administered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have a history of liver or kidney disease, asthma, chronic bronchitis, or emphysema. Do not use this medicine for a chronic cough that persists for more than 7 days, or if you have a cough with excessive phlegm, unless directed by a doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness. Do not drink alcohol while taking this medicine, as it can increase drowsiness and other side effects. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Do not use this medicine to make a child sleepy. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and confusion. Use with caution and consult a doctor for appropriate dosing. They may also have a higher risk of drug interactions due to polypharmacy.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, consult your doctor before taking this medicine, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may cause dry mouth or interact with anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Light exercise like walking may be fine if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to work if you do not experience these side effects, but take precautions.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if your cough persists for more than 7 days, if it comes back, or if you experience fever, rash, or persistent headache. Also stop if you experience any serious side effects.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of guaifenesin may increase the risk of kidney stones. Dextromethorphan can lead to dependence or tolerance with extended use. If your cough persists for more than 7 days, consult a doctor to determine the underlying cause.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and soothe airways.
Evidence: Well-establishedSoothes sore throat and suppresses cough.
Evidence: LimitedHelps clear nasal congestion.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription in case you need to show it at customs or security. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue taking the medicine as needed for cough, but do not exceed the maximum daily dose. Keep it in your carry-on luggage if flying, and ensure it is properly sealed to prevent leakage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 15 to 30 minutes after taking it, providing relief from cough for about 4 to 6 hours.
A: You should consult a doctor or pharmacist before taking this medicine with other cold medicines, as they may contain overlapping ingredients or interact.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor before use.
A: This medicine may contain sugar or alcohol. Consult your doctor or pharmacist before use if you have diabetes.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: This medicine is effective for dry cough and congestion but may not be suitable for all types of cough, especially productive cough with excessive mucus. - Myth: It is safe to take more than the recommended dose for faster relief.
Fact: Taking more than the recommended dose can lead to serious side effects and is not recommended. - Myth: This medicine is safe for children under 4 years.
Fact: This medicine is not recommended for children under 4 years of age.
🔄 Alternative Options
Generic Alternatives
- Dextromethorphan + Guaifenesin oral liquid