clechest syrup - Guaifenesin (100mg) + Terbutaline (2.5mg) medicine

Asthakind Tablet: Complete Medicine Guide

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🏭 Biotric Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 27, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited for the combination; Guaifenesin is well-established as an expectorant, and Terbutaline is well-established as a bronchodilator.
Reviewed by
SaathiMed Expert Panel | Oct 27, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in sputum or vomit
  • Severe chest pain or difficulty breathing
  • Irregular or very fast heartbeat
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is clechest syrup used for?

This medicine is a combination of Guaifenesin (an expectorant) and Terbutaline (a bronchodilator) used to relieve cough with mucus and mild breathing difficulty. It works by thinning mucus and opening airways. It is usually taken two to three times a day with food, as prescribed by a doctor.

  • Generic Name: Guaifenesin + Terbutaline
  • Manufacturer: Biotric Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 clechest syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ग्वाइफेनेसिन और टर्बुटालीन का संयोजन है। यह बलगम वाली खांसी और हल्की सांस की तकलीफ में राहत देती है। ग्वाइफेनेसिन बलगम को पतला करता है जिससे खांसी में बलगम बाहर निकलना आसान हो जाता है। टर्बुटालीन श्वास नलियों की मांसपेशियों को ढीला करता है जिससे सांस लेने में आसानी होती है। यह दवा ब्रोंकाइटिस और श्वसन संक्रमण में उपयोगी है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट खराब, सिरदर्द, चक्कर आना, घबराहट, कंपन और धड़कन तेज होना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि सांस लेने में कठिनाई, छाती में दर्द, या त्वचा पर चकत्ते हों तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट खराब न हो। पर्याप्त पानी पिएं। शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। यदि आपको दिल की बीमारी, उच्च रक्तचाप, मधुमेह, थायरॉइड, या गुर्दे/यकृत की समस्या है तो डॉक्टर को बताएं। बिना सलाह के लंबे समय तक न लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 clechest syrup Uses & Benefits

[{"condition":"Productive cough with mucus","description":"Helps loosen and thin mucus, making it easier to cough out.","evidence":"Well-established for Guaifenesin"},{"condition":"Acute bronchitis","description":"Provides symptomatic relief of cough and mild bronchospasm.","evidence":"Limited"},{"condition":"Mild bronchospasm associated with respiratory infections","description":"Terbutaline helps relax airway muscles and improve airflow.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Productive cough with mild bronchospasm

Also treats: Acute bronchitis, Respiratory tract infections

📋 Drug Information

Generic Name(s)Guaifenesin + Terbutaline
Brand NameAsthakind Expectorant Sugar Free
ManufacturerBiotric Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassExpectorant and Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day to help loosen mucus.
3
Avoid alcohol while taking this medicine as it may increase drowsiness and dizziness.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual heart palpitations or tremors to your doctor.
7
Do not use this medicine for a dry cough; it is meant for productive cough with mucus.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not effective for dry cough.
Not Primary
✅
Mild wheezing
Terbutaline component helps relieve mild bronchospasm.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGuaifenesin is rapidly absorbed from the gastrointestinal tract. Terbutaline is well absorbed orally, but undergoes some first-pass metabolism.
DistributionGuaifenesin is distributed to body tissues, including the respiratory tract. Terbutaline distributes widely, with some protein binding.
Protein BindingTerbutaline is approximately 25% bound to plasma proteins. Guaifenesin's protein binding is not well established.
MetabolismGuaifenesin is metabolized in the liver. Terbutaline undergoes conjugation in the liver to inactive metabolites.
Half-LifeGuaifenesin half-life is approximately 1 hour. Terbutaline half-life is approximately 3 to 4 hours.
ExcretionGuaifenesin and its metabolites are excreted mainly in urine. Terbutaline is excreted primarily in urine as unchanged drug and metabolites.
BioavailabilityGuaifenesin oral bioavailability is not well established. Terbutaline oral bioavailability is approximately 10-15% due to first-pass metabolism.
Onset of ActionGuaifenesin onset is within 30 minutes. Terbutaline onset is within 30-60 minutes after oral administration.
Peak Plasma TimeGuaifenesin peak plasma time is about 1 hour. Terbutaline peak plasma time is about 2-3 hours.
Duration of ActionGuaifenesin duration is about 4-6 hours. Terbutaline duration is about 4-6 hours.

How It Works

This medicine combines two active ingredients. Guaifenesin is an expectorant that works by increasing the volume and reducing the viscosity of mucus in the respiratory tract, making it easier to cough out. Terbutaline is a selective beta-2 adrenergic agonist that relaxes bronchial smooth muscle by stimulating beta-2 receptors, leading to bronchodilation and improved airflow.

Mechanism Steps

1
Guaifenesin action: Guaifenesin stimulates respiratory tract secretions, increasing the volume of mucus and reducing its viscosity, which helps in coughing out mucus.
2
Terbutaline binding: Terbutaline binds to beta-2 adrenergic receptors on bronchial smooth muscle cells.
3
Bronchodilation: This binding activates intracellular signaling that relaxes the smooth muscles, widening the airways and improving airflow.

💡 How to Take clechest syrup

Strength: Tablet: Guaifenesin 100 mg + Terbutaline 2.5 mg

1Take this medicine orally with a glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take it at the same times each day to maintain consistent levels.
5Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two to three times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects. Use with caution and adjust dose as needed under medical supervision.
Renal ImpairmentDose adjustment may be needed in patients with renal impairment. Consult your doctor.
Hepatic ImpairmentDose adjustment may be needed in patients with hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets in 24 hours, unless otherwise prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase nervousness and palpitations.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of clechest syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Tremor (Common (5-10%))
Usually decreases with continued use. Consult doctor if bothersome.
Palpitations (Common (5-10%))
Report to doctor if persistent or associated with chest pain.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Irregular heartbeat (arrhythmia) (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, chest pain, or fainting.
Paradoxical bronchospasm (Rare (<0.1%))
If breathing difficulty worsens after taking this medicine, stop and seek immediate medical help.

⚠️ Rare Side Effects

Hypokalemia
Report muscle weakness or cramps to your doctor.
Hyperglycemia
Monitor blood sugar if diabetic and inform doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Digoxin Moderate
Corticosteroids Moderate
Caffeine Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Digoxin
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Guaifenesin or Terbutaline","Severe cardiac disease","Uncontrolled hypertension","Severe hepatic or renal impairment","Children under 12 years"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","Use with caution in patients with diabetes mellitus, as Terbutaline may increase blood glucose.","Use with caution in patients with hyperthyroidism.","Use with caution in patients with seizure disorders.","Do not exceed the recommended dose.","Avoid abrupt discontinuation after prolonged use."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe tachycardia, tremor, palpitations, nausea, and vomiting. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Take it with food to reduce stomach upset. Drink plenty of water to help loosen mucus. Avoid alcohol while taking this medicine as it may increase drowsiness and dizziness. Do not drive or operate heavy machinery if you feel dizzy or shaky. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or liver or kidney disease. Do not use this medicine for a prolonged period without medical supervision. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the cardiovascular effects of Terbutaline, such as palpitations and increased heart rate. Use with caution and monitor blood pressure and heart rate regularly.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant or are pregnant. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks before prescribing.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and affect heart rate and blood pressure.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth or interact with medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of fluids to help thin mucus.
🥗
Use a humidifier to keep the air moist.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get adequate rest to support recovery.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid allergens and irritants that trigger coughing.

🏋️ Exercise Considerations

Avoid strenuous exercise while you have a cough and breathing difficulty. Rest until symptoms improve. Consult your doctor before resuming exercise.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold and processed foods.
Eat a balanced diet rich in vitamins and minerals.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, tremor, or palpitations, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. Take rest as needed.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of Terbutaline may lead to tolerance and reduced effectiveness. Regular monitoring of heart rate, blood pressure, and potassium levels may be required. Consult your doctor for alternative treatments if long-term therapy is needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal irrigation

Can help clear nasal passages and reduce postnasal drip.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust the dosing schedule as advised by your doctor. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
He was prescribed this medicine for a productive cough and mild wheezing. After taking it with food twice daily for 5 days, his cough and breathing improved significantly. He experienced mild tremor initially, which subsided after a few days.
💡 Lesson: Taking the medicine with food and completing the prescribed course helps in better symptom relief and reduces side effects.
👤 A 50-year-old woman with a history of hypertension
She was given this medicine for a cough with mucus. Her blood pressure was monitored regularly. She was advised to avoid caffeine and alcohol. Her cough improved, but she reported palpitations, so the doctor reduced the dose.
💡 Lesson: Patients with heart conditions should use this medicine with caution and under medical supervision, and report any cardiac symptoms promptly.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after oral administration. You may notice relief from cough and breathing difficulty within a few hours.

Q: Can I take this medicine with other cough medicines?

A: Do not take other cough medicines without consulting your doctor, as they may contain overlapping ingredients or interact with this medicine.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children below 12 years without medical advice. Consult a pediatrician for appropriate dosing.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for clechest syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine provides symptomatic relief but does not cure asthma. It should not replace prescribed asthma controller medications.
  • Myth: It is safe to take this medicine for any type of cough.
    Fact: This medicine is for productive cough with mucus. It is not effective for dry cough and may not be appropriate for all types of cough.

🔄 Alternative Options

Generic Alternatives

  • Guaifenesin + Terbutaline tablets from other manufacturers

📊 Comparison with Similar Medicines

[{"medicine":"Guaifenesin + Terbutaline","composition":"Guaifenesin 100 mg + Terbutaline 2.5 mg","uses":"Productive cough with mild bronchospasm","notes":"Combination of expectorant and bronchodilator"},{"medicine":"Guaifenesin + Salbutamol","composition":"Guaifenesin 100 mg + Salbutamol 2 mg","uses":"Productive cough with bronchospasm","notes":"Salbutamol is a shorter-acting bronchodilator"}]

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