Amazeo OD 100 Tablet SR (Amisulpride 100 mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- High fever with severe muscle stiffness, confusion, or sweating
- Fainting, palpitations, or irregular heartbeat
- New involuntary movements of the face, tongue, lips, or limbs
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain
- Frequent infections, fever, or severe sore throat
- Seizure or loss of consciousness
- Severe dizziness or inability to stand up
If experiencing severe symptoms, call emergency services immediately.
What is cizorest 100 od tablet sr used for?
This medicine contains Amisulpride 100 mg, an atypical antipsychotic used to treat schizophrenia and psychotic disorders. It works by blocking dopamine D2 and D3 receptors in the brain. It is taken orally as a sustained-release tablet, usually once daily. The dose must be individualized by a qualified clinician. Common side effects include sleepiness, dizziness, dry mouth, constipation, weight gain, and hormonal changes. Do not stop this medicine suddenly without medical advice.
- Generic Name: Amisulpride
- Manufacturer: Cipla Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cizorest 100 od tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा एमिसलप्राइड 100 मिलीग्राम से बनी है और मानसिक रोगों के इलाज में इस्तेमाल होती है। इसका मुख्य उपयोग सिज़ोफ्रेनिया और अन्य मानसिक विकारों में किया जाता है, जिनमें मरीज़ को भ्रम, मतिभ्रम, सामाजिक अलगाव और कम प्रेरणा जैसी समस्याएँ होती हैं। यह दवा दिमाग में डोपामिन नामक रसायन को संतुलित करके काम करती है। यह केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और डॉक्टर की सलाह के बिना बंद नहीं करनी चाहिए।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं, जैसे नींद आना, चक्कर आना, मुँह सूखना, कब्ज़, वजन बढ़ना और स्तनों में दर्द या दूध आना। कुछ लोगों में हाथ-पैर काँपना, अकड़न या बेचैनी भी हो सकती है। अगर आपको तेज़ बुखार, मांसपेशियों में अकड़न, भ्रम, धड़कन तेज़ होना या बेहोशी जैसी समस्या हो, तो तुरंत डॉक्टर से मिलें। इस दवा को अचानक बंद न करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को पानी के साथ पूरा निगलें, चबाएँ या तोड़ें नहीं। इसे हर दिन एक ही समय पर लें। शराब न पिएँ, क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी न चलाएँ और मशीन न चलाएँ। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएँ। अगर आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें।
💊 cizorest 100 od tablet sr Uses & Benefits
[{"condition":"Schizophrenia","description":"This medicine is used to treat schizophrenia, including both positive symptoms such as hallucinations and delusions, and negative symptoms such as social withdrawal and lack of motivation.","evidence":"Well-established"},{"condition":"Acute psychotic episodes","description":"This medicine may be used for short-term management of acute psychotic episodes under specialist supervision.","evidence":"Well-established"},{"condition":"Negative symptoms of schizophrenia","description":"This medicine is often chosen when negative symptoms are prominent, because it may help with motivation and social engagement at appropriate doses.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Treatment-resistant depression","description":"Sometimes used as an add-on treatment in selected patients with depression that has not responded to standard antidepressants.","evidence":"Limited"},{"condition":"Bipolar disorder","description":"Occasionally used off-label for mood stabilisation in bipolar disorder, but this is not a first-line use.","evidence":"Limited"}]
Primary treatment for: Schizophrenia
Also treats: Acute psychotic episodes, Negative symptoms of schizophrenia
📋 Drug Information
| Generic Name(s) | Amisulpride |
| Brand Name | Amisant 200 Tablet |
| Manufacturer | Cipla Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Atypical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in a dry place. Keep it in its original container, tightly closed, and away from direct sunlight and moisture. Do not store it in the bathroom. Keep all medicines out of the reach of children and pets. |
| Shelf Life | The shelf life of this medicine is usually 24 months from the date of manufacture, but you should always check the expiry date printed on the pack. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking dopamine D2 and D3 receptors in the brain. At low doses, it mainly blocks presynaptic D2 and D3 autoreceptors, which can increase dopamine release in some brain regions and may help with negative symptoms. At higher doses, it blocks postsynaptic D2 receptors, which helps to reduce positive psychotic symptoms such as hallucinations and delusions. It has little effect on serotonin, histamine, or muscarinic receptors compared with many other antipsychotics, which is why it tends to cause fewer anticholinergic side effects and less sedation than some older medicines.
Mechanism Steps
💡 How to Take cizorest 100 od tablet sr
Strength: Sustained-release tablet containing Amisulpride 100 mg.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, kidney function, liver function, and response to treatment. For schizophrenia, treatment is often started at a low dose and increased gradually. The usual effective dose range is between 50 mg and 800 mg per day, depending on whether negative or positive symptoms are being treated. Doses above 400 mg per day are generally used only for positive symptoms and should be managed by a specialist. The sustained-release tablet is usually taken once daily. Do not change the dose without your doctor's advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially sedation, dizziness, low blood pressure, and movement problems. Treatment is usually started at a lower dose and increased more slowly. Kidney function often declines with age, so the dose may need to be reduced. Older adults with dementia-related psychosis may have an increased risk of stroke and death when taking antipsychotic medicines, so this medicine should be used with caution in this group. |
| Renal Impairment | This medicine is mainly removed by the kidneys, so the dose must be reduced in people with kidney problems. In mild kidney impairment, the dose may be reduced by half. In moderate kidney impairment, the dose may be reduced to one-third. This medicine is contraindicated in severe kidney impairment. Your doctor will check your kidney function and adjust the dose accordingly. |
| Hepatic Impairment | This medicine undergoes limited liver metabolism, so dose adjustment is usually not needed in people with mild to moderate liver problems. However, people with severe liver disease should be monitored closely, and the dose may need to be adjusted based on clinical response and side effects. |
| Maximum Daily Dose | The maximum daily dose of this medicine is usually 800 mg per day, but doses above 400 mg per day should only be used under specialist supervision for positive symptoms. Doses above 800 mg per day are not recommended. The exact maximum dose for you will be determined by your doctor based on your condition and kidney function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cizorest 100 od tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other antipsychotics | Major | |
| QT-prolonging medicines | Major | |
| Levodopa | Major | |
| Blood pressure medicines | Moderate | |
| Alcohol | Moderate | |
| Potassium-lowering medicines | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Other dopamine-blocking medicines
- Medicines that prolong the QT interval
- Levodopa and dopamine agonists
⚡ Moderate Interactions
- Blood pressure medicines
- Alcohol
- Medicines that lower potassium or magnesium
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of low blood pressure. It can also worsen the sedative effects of this medicine and make it harder to judge your reactions. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to amisulpride or any ingredient in this medicine","Prolactin-dependent tumours such as prolactin-secreting pituitary adenoma or breast cancer","Severe kidney impairment","Certain heart rhythm disorders or a history of QT prolongation","Low potassium or magnesium levels that are not corrected","A history of agranulocytosis","Use with levodopa or dopamine agonists unless specifically advised by a specialist"]
⚠️ Warnings & Precautions
["This medicine can cause sedation. Avoid driving or operating machinery until you know how it affects you.","Do not stop this medicine suddenly, as this can cause withdrawal symptoms or a return of your original symptoms.","Tell your doctor if you have a history of heart problems, kidney problems, liver problems, or seizures.","This medicine can raise prolactin levels and may affect fertility. Discuss with your doctor if you are planning pregnancy.","Older adults with dementia-related psychosis may have an increased risk of stroke and death when taking antipsychotic medicines. This medicine should be used with caution in this group.","Avoid alcohol while taking this medicine.","Tell your doctor about all other medicines you take, including over-the-counter medicines and herbal products."]
🤱 Lactation Safety
This medicine passes into breast milk. Because it can affect the baby's developing nervous system, breastfeeding is generally not recommended while taking this medicine. If you wish to breastfeed, discuss the risks and benefits with your doctor, who may recommend an alternative treatment or monitoring of the baby.
💊 Overdose Management
If you or someone else takes too much of this medicine, seek emergency medical help immediately. Symptoms of overdose may include severe drowsiness, low blood pressure, fast or irregular heartbeat, and confusion. Do not try to make yourself vomit unless told to do so by a medical professional. Treatment is supportive and may include monitoring of heart rhythm, blood pressure, and breathing. Take the medicine packaging with you to the hospital so the medical team knows exactly what was taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as your doctor prescribes. Swallow the sustained-release tablet whole with water; do not crush, chew, or break it, because that can change how the medicine is released in your body. You may take it with or without food, but taking it at the same time each day helps to keep steady levels in your body. Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness. Be careful when driving or operating machinery until you know how this medicine affects you. Tell your doctor about all other medicines you take, especially blood pressure medicines, heart rhythm medicines, and other medicines that affect dopamine. Do not stop this medicine suddenly on your own. If you miss a dose, follow your doctor's or pharmacist's advice. Keep all follow-up appointments so your doctor can check your symptoms, weight, blood sugar, heart rhythm, and prolactin levels when needed. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before taking this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the side effects of this medicine, especially sedation, dizziness, low blood pressure, and movement problems. Treatment is usually started at a lower dose and increased more slowly. Kidney function often declines with age, so the dose may need to be reduced. Older adults with dementia-related psychosis may have an increased risk of stroke and death when taking antipsychotic medicines, so this medicine should be used with caution in this group.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, talk to your doctor before you conceive. This medicine may affect fertility by raising prolactin levels. Your doctor may adjust your treatment or switch you to a different medicine. Do not stop this medicine on your own. If you become pregnant while taking this medicine, contact your doctor immediately.
🏥 Post-Surgery Considerations
Tell your surgeon and anaesthetist that you are taking this medicine before any surgery. This medicine can interact with anaesthetic medicines and affect blood pressure and heart rhythm. Your doctor may advise you to stop or adjust the dose before surgery. Do not stop it on your own. After surgery, follow your doctor's advice about when to restart the medicine.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine before any dental procedure. This medicine can cause dry mouth, which may increase the risk of dental problems. It can also cause dizziness or low blood pressure, so you may need to be careful when getting up from the dental chair. If you need sedation or anaesthesia for a dental procedure, inform the dentist about all your medicines.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness, dizziness, and low blood pressure, especially when you first start taking it or when the dose is increased. Be careful with exercises that require balance or quick movements. Stand up slowly to avoid dizziness. If you feel faint or very tired during exercise, stop and rest. Talk to your doctor before starting a new exercise programme.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, especially when you first start taking it or when the dose is increased. Avoid driving or operating heavy machinery until you know how it affects you. It may also affect your concentration. Talk to your employer or school if you need adjustments. With the right dose and support, many people are able to continue their daily activities and work.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when and how to stop it, usually by reducing the dose gradually. Stopping suddenly can cause withdrawal symptoms or a return of your original symptoms. If you experience troublesome side effects, contact your doctor, who may adjust the dose or change the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may be needed to control schizophrenia and prevent relapse. Regular monitoring is important for weight, blood sugar, lipid profile, heart rhythm, and prolactin levels. Some people may develop movement disorders with long-term use, so your doctor will assess you regularly. Do not stop this medicine without medical advice, as stopping suddenly can cause withdrawal symptoms or a return of your original symptoms.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help manage symptoms and improve coping skills alongside medicine.
Evidence: Well-establishedHelps families understand the illness and support the patient.
Evidence: Well-establishedCan improve social functioning and daily living skills.
Evidence: ModerateRegular exercise, healthy diet, and good sleep can support overall mental health.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known vaccine interactions with this medicine. However, if you are due for any vaccination, inform the healthcare provider that you are taking this medicine. If you have a fever or are unwell, it is usually best to postpone vaccination until you have recovered.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the label intact
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of the reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a doctor's letter explaining that you need this medicine. Keep enough supply for your entire trip, plus extra in case of delays. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, ask your doctor how to adjust the timing of your dose. Do not pack it in checked luggage; keep it in your hand luggage. Check the customs rules of your destination country for controlled medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Improvement in psychotic symptoms usually begins within a few days to a few weeks. Full benefits may take several weeks. Your doctor will monitor your response and adjust the dose if needed.
A: No. Alcohol can increase drowsiness, dizziness, and the risk of low blood pressure. It is best to avoid alcohol while taking this medicine.
A: If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time, skip the missed dose and continue with your regular schedule. Do not take a double dose.
A: No. Stopping suddenly can cause withdrawal symptoms or a return of your original symptoms. Always talk to your doctor before stopping.
A: This medicine should be used during pregnancy only if the potential benefit clearly outweighs the potential risk. Talk to your doctor if you are pregnant or planning pregnancy.
A: Weight gain can occur with this medicine. Following a balanced diet and staying physically active can help. Your doctor will monitor your weight during treatment.
🤔 Common Patient Concerns
🔄 Substitutes for cizorest 100 od tablet sr
View AllAlternative brands with exact same active ingredient:
-
davaindia amisulpride 100mg tabletDavaindia Generic Pharmacy ₹40.00 62.6% CHEAPER
-
stayhappi amisulpride 100mg tabletSarvagunaushdhi Pvt Ltd ₹70.31 34.3% CHEAPER
-
stozen 100mg tabletKonark Lifesciences Pvt Ltd ₹71.25 33.4% CHEAPER
-
amicalm 100mg tabletTriton Healthcare Pvt Ltd ₹72.11 32.6% CHEAPER
-
NORMENTA 100MG TABLETIpca Laboratories Ltd ₹74.06 30.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is addictive.
Fact: This medicine is not habit-forming in the way that opioids or benzodiazepines are. However, it should not be stopped suddenly without medical advice. - Myth: This medicine will cure schizophrenia permanently.
Fact: This medicine helps control symptoms but does not cure schizophrenia. It is usually part of a long-term treatment plan that includes therapy and lifestyle support. - Myth: You can stop this medicine as soon as you feel better.
Fact: Stopping suddenly can cause withdrawal symptoms or a return of your original symptoms. Always talk to your doctor before stopping. - Myth: This medicine is only for severe mental illness.
Fact: This medicine is mainly used for schizophrenia and psychotic disorders. It is not a general mood booster and should only be used when prescribed.
🔄 Alternative Options
Generic Alternatives
- Amisulpride 100 mg sustained-release tablet
Brand Alternatives
- Amazeo OD 100 Tablet SR