citajoy c 0.5 mg/5 mg tablet - Clonazepam (0.5mg) + Escitalopram Oxalate (5mg) medicine

Azjoy Plus 0.5mg/5mg Tablet: Complete Medicine Guide

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🏭 Wings Biotech Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Not established from the available information. Both clonazepam and escitalopram have potential risks during pregnancy. Use only if clearly needed and under specialist supervision. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for individual components; limited for the fixed-dose combination.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Swelling of face, lips, tongue, or throat
  • Chest pain or irregular heartbeat
  • Severe confusion, agitation, or hallucinations
  • Suicidal thoughts or self-harm urges
  • Unusual bleeding or bruising
  • Severe muscle rigidity or fever
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is citajoy c 0.5 mg/5 mg tablet used for?

This medicine is a prescription combination of clonazepam 0.5 mg and escitalopram 5 mg used to treat anxiety disorders. It works by enhancing GABA and serotonin activity in the brain. It should be taken exactly as prescribed and not stopped suddenly.

  • Generic Name: Clonazepam + Escitalopram
  • Manufacturer: Wings Biotech Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 citajoy c 0.5 mg/5 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोनाजेपम 0.5 मिलीग्राम और एस्सिटालोप्राम 5 मिलीग्राम का संयोजन है, जिसका उपयोग चिंता विकार, पैनिक अटैक और अवसाद के इलाज के लिए किया जाता है। यह मस्तिष्क में GABA और सेरोटोनिन के स्तर को बढ़ाकर काम करती है, जिससे मन शांत होता है और चिंता कम होती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और डॉक्टर की सलाह के बिना इसे अचानक बंद नहीं करना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, थकान, मुँह सूखना, जी मिचलाना और नींद में गड़बड़ी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें एलर्जी, सेरोटोनिन सिंड्रोम, हृदय की धड़कन में अनियमितता और रक्तस्राव का खतरा बढ़ना शामिल है। यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, सीने में दर्द या गंभीर भ्रम हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। डॉक्टर की सलाह के बिना खुराक न बदलें और न ही अचानक बंद करें। शराब और अन्य नींद लाने वाली दवाओं से बचें क्योंकि इससे नींद और सांस की समस्या बढ़ सकती है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। अपने डॉक्टर को अपनी सभी दवाओं और सप्लीमेंट्स के बारे में बताएं। नियमित जांच के लिए डॉक्टर के पास जाते रहें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 citajoy c 0.5 mg/5 mg tablet Uses & Benefits

[{"condition":"Panic disorder with or without agoraphobia","description":"This combination helps reduce the frequency and intensity of panic attacks while managing anticipatory anxiety.","evidence":"Well-established for the individual components; combination use is based on clinical practice."},{"condition":"Generalized anxiety disorder (GAD)","description":"Escitalopram provides long-term anxiety control, while clonazepam offers rapid relief of acute anxiety symptoms.","evidence":"Well-established for individual components; combination use is common in clinical practice."},{"condition":"Social anxiety disorder","description":"May be prescribed when a patient needs both immediate and sustained relief from social anxiety symptoms.","evidence":"Moderate evidence for individual components; combination use is off-label."},{"condition":"Mixed anxiety and depressive disorder","description":"The combination addresses both anxiety and depressive symptoms, which often occur together.","evidence":"Limited evidence for the fixed-dose combination; clinical experience supports use."}]

Off-label uses: [{"condition":"Insomnia associated with anxiety","description":"Clonazepam component may help with sleep, but this is not a primary indication for the combination.","evidence":"Limited"},{"condition":"Premenstrual dysphoric disorder (PMDD)","description":"Escitalopram is sometimes used for PMDD, but the combination with clonazepam is not standard.","evidence":"Limited"}]

Primary treatment for: Anxiety disorders

Also treats: Panic disorder, Generalized anxiety disorder, Social anxiety disorder, Mixed anxiety and depressive disorder

📋 Drug Information

Generic Name(s)Clonazepam + Escitalopram
Brand NameAsiclopam Tablet
ManufacturerWings Biotech Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassBenzodiazepine + SSRI
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Avoid alcohol completely while taking this medicine to prevent dangerous sedation.
3
Do not drive or operate heavy machinery until you know how this medicine affects you.
4
Never stop this medicine abruptly; your doctor will taper the dose gradually to prevent withdrawal.
5
Report any unusual mood changes, suicidal thoughts, or signs of serotonin syndrome immediately.
6
Keep all follow-up appointments for monitoring of liver, kidney, and electrolyte levels.
7
Inform your dentist or surgeon about this medicine before any procedure.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Frequent panic attacks
This medicine is commonly prescribed for this.
Likely Use
✅
Excessive worry or anxiety
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClonazepam is well absorbed after oral administration, with a bioavailability of approximately 90%. Escitalopram is also well absorbed, with a bioavailability of about 80%. Food does not significantly affect the absorption of either component.
DistributionClonazepam is highly lipophilic and distributes widely into body tissues, including the brain. Escitalopram has a volume of distribution of about 12 L/kg. Both components cross the blood-brain barrier.
Protein BindingClonazepam is approximately 85% bound to plasma proteins. Escitalopram is about 56% bound to plasma proteins.
MetabolismClonazepam is metabolized in the liver primarily by CYP3A4 to inactive metabolites. Escitalopram is metabolized in the liver by CYP2C19 and CYP3A4 to less active metabolites.
Half-LifeClonazepam half-life is 30-40 hours. Escitalopram half-life is approximately 27-32 hours.
ExcretionClonazepam metabolites are excreted mainly in urine (50-70%) and feces (10-30%). Escitalopram is excreted in urine (approximately 56%) and feces (approximately 20%) as metabolites.
BioavailabilityClonazepam: approximately 90%. Escitalopram: approximately 80%.
Onset of ActionClonazepam: 30-60 minutes for anxiolytic effects. Escitalopram: 1-2 weeks for initial antidepressant/anxiolytic effects, with full benefits in 4-6 weeks.
Peak Plasma TimeClonazepam: 1-4 hours. Escitalopram: 4-5 hours.
Duration of ActionClonazepam: 6-12 hours. Escitalopram: continuous with steady-state levels; clinical effects persist with regular dosing.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Clonazepam binds to the benzodiazepine site on the GABA-A receptor, enhancing the inhibitory effect of GABA, which calms overactive nerve signals. Escitalopram selectively inhibits the serotonin transporter (SERT), increasing serotonin levels in the synaptic cleft, which helps regulate mood and anxiety over time. Together, they provide rapid anxiety relief (clonazepam) and longer-term mood stabilization (escitalopram).

Mechanism Steps

1
Clonazepam binds to GABA-A receptor: Clonazepam attaches to the benzodiazepine binding site on the GABA-A receptor, increasing the frequency of chloride channel opening.
2
Enhanced GABA inhibition: Increased chloride influx hyperpolarizes neurons, reducing their excitability and producing a calming effect.
3
Escitalopram inhibits serotonin reuptake: Escitalopram blocks the serotonin transporter, preventing serotonin from being reabsorbed into the presynaptic neuron.
4
Increased synaptic serotonin: Higher serotonin levels in the synapse enhance postsynaptic serotonin receptor activation, improving mood and reducing anxiety over weeks.

💡 How to Take citajoy c 0.5 mg/5 mg tablet

Strength: Tablet containing clonazepam 0.5 mg and escitalopram oxalate 5 mg.

1Take this medicine orally with a glass of water.
2Take it at the same time each day to maintain consistent levels.
3You may take it with or without food, but taking it with food may reduce stomach upset.
4Swallow the tablet whole; do not crush or chew.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.
7Do not stop taking this medicine abruptly without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, as prescribed by your doctor. The dose may be adjusted based on your response and tolerability. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Monitor for falls, confusion, and excessive sedation.
Renal ImpairmentDose adjustment may be needed in patients with renal impairment. Consult your doctor for personalized dosing.
Hepatic ImpairmentDose adjustment is recommended in patients with hepatic impairment. Use with caution and monitor liver function.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. Typically, clonazepam should not exceed 20 mg/day and escitalopram should not exceed 20 mg/day. However, this combination's maximum dose must be determined by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases sedation and respiratory depression risk.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of citajoy c 0.5 mg/5 mg tablet

✅ Common Side Effects

Drowsiness (Common (10-30%))
Avoid driving or operating machinery. Usually improves with time. Consult doctor if persistent.
Dizziness (Common (5-15%))
Rise slowly from sitting or lying positions. Stay hydrated.
Fatigue (Common (5-15%))
Ensure adequate rest. If severe, consult doctor.
Dry mouth (Common (5-10%))
Sip water, chew sugar-free gum, or use saliva substitutes.
Nausea (Common (5-10%))
Take with food. If persistent, consult doctor.

🚨 Serious Side Effects

Serotonin syndrome (Rare (<0.1%))
Seek immediate medical attention if you have agitation, hallucinations, rapid heart rate, fever, or muscle rigidity.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, tongue, or throat, or difficulty breathing.
Abnormal heart rhythms (QT prolongation) (Rare (<0.1%))
Seek medical help if you feel faint, dizzy, or have palpitations.
Increased bleeding risk (Rare (<0.1%))
Report unusual bruising or bleeding to your doctor immediately.

⚠️ Rare Side Effects

Hallucinations
Contact doctor immediately.
Blood disorders (e.g., agranulocytosis)
Seek medical attention if you develop fever, sore throat, or unusual infections.
Severe mood changes or suicidal thoughts
Contact doctor or emergency services immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Opioids Major
Warfarin Major
Ketoconazole Moderate
Omeprazole Moderate
Fluoxetine Moderate
Diuretics Moderate
Antacids Minor
Grapefruit juice Minor
Caffeine Minor

🚨 Major Interactions

  • MAO inhibitors (e.g., phenelzine, tranylcypromine)
  • Other CNS depressants (e.g., opioids, alcohol, barbiturates)
  • Anticoagulants/antiplatelets (e.g., warfarin, aspirin, NSAIDs)

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • CYP2C19 inhibitors (e.g., omeprazole, fluoxetine)
  • Diuretics

🍷 Alcohol Interaction

Alcohol should be completely avoided while taking this medicine. It can increase drowsiness, dizziness, and the risk of respiratory depression, and it may worsen anxiety and depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clonazepam, escitalopram, or any component of the formulation","Concurrent use with MAO inhibitors","Severe liver disease","Severe kidney disease","Narrow-angle glaucoma","Myasthenia gravis","Severe respiratory insufficiency","Pregnancy (unless clearly needed)","Breastfeeding"]

⚠️ Warnings & Precautions

["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","Do not stop abruptly; withdrawal symptoms may occur.","May increase risk of suicidal thoughts, especially in young adults; monitor closely.","Avoid alcohol and other CNS depressants.","Use with caution in elderly; increased risk of falls and confusion.","May cause serotonin syndrome when combined with other serotonergic drugs.","May increase bleeding risk, especially with NSAIDs or anticoagulants.","Not recommended for children."]

🤱 Lactation Safety

Both clonazepam and escitalopram are excreted in breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor after weighing benefits and risks.

💊 Overdose Management

Overdose can cause severe drowsiness, confusion, coma, respiratory depression, and cardiac arrhythmias. Seek emergency medical attention immediately. Treatment is supportive and symptomatic. Flumazenil may be used for benzodiazepine overdose but is contraindicated in mixed overdose with tricyclic antidepressants. Activated charcoal may be considered if within 1-2 hours of ingestion. Monitor vital signs and ECG.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed. Do not change the dose or stop suddenly without consulting your doctor. Avoid alcohol and other sedatives because they can increase drowsiness and breathing problems. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor about all other medicines, supplements, and herbal products you take. Keep all follow-up appointments for monitoring. Store this medicine in its original container at room temperature, away from moisture and direct sunlight. Keep out of reach of children. If you miss a dose, follow your doctor's instructions; do not double the dose. If you experience any unusual symptoms, contact your healthcare provider immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative effects of clonazepam and may experience increased confusion, falls, and fractures. Escitalopram may increase the risk of hyponatremia. Start with lower doses and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor well in advance. Both clonazepam and escitalopram may pose risks to the fetus. Your doctor may recommend switching to a safer alternative or tapering off the medicine gradually.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with anesthetic agents and increase sedation. Your doctor may advise temporary discontinuation or dose adjustment.

🦷 Dental Procedures

Inform your dentist about this medicine before any dental procedure. It may interact with local anesthetics or sedatives used during dental work. Your dentist may need to adjust the medications used.

💚 Lifestyle Tips for Better Results

🏃
Maintain a regular sleep schedule to support mood stability.
🥗
Engage in regular physical activity like walking or yoga to reduce anxiety.
😴
Practice relaxation techniques such as deep breathing or meditation.
💧
Avoid caffeine and nicotine, which can worsen anxiety.
🧘
Stay connected with supportive friends and family.
🌞
Keep a symptom diary to track your progress and share with your doctor.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness, which can affect coordination. Avoid high-risk activities like swimming, cycling, or using heavy machinery until you know how it affects you. Light to moderate exercise is generally safe and beneficial.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits, vegetables, and whole grains.
Include omega-3 fatty acids from fish or flaxseed.
Limit processed foods and added sugars.
Stay well hydrated throughout the day.
Avoid alcohol and excessive caffeine.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and impair concentration, especially during the first few weeks. Avoid driving or operating machinery until you know how it affects you. Inform your employer if your job involves safety-sensitive tasks. With time, most people adjust, but some may need dose adjustments.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Your doctor will gradually reduce the dose to prevent withdrawal symptoms and relapse. If you experience severe side effects, contact your doctor immediately for guidance.

📅 Long-Term Use Effects

Long-term use of clonazepam can lead to tolerance, dependence, and withdrawal symptoms upon discontinuation. Escitalopram is generally safe for long-term use but may cause sexual dysfunction, weight changes, and emotional blunting. Regular monitoring of mood, liver function, and electrolytes is recommended. Periodic reassessment of the need for continued therapy is essential.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive behavioral therapy (CBT)

Can be as effective as medication for anxiety disorders and provides long-term coping skills.

Evidence: Well-established
Mindfulness and meditation

Helps reduce anxiety and improve emotional regulation.

Evidence: Moderate
Regular exercise

Has been shown to reduce anxiety and improve mood.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your doctor about this medicine before receiving any vaccine, especially live vaccines, as a precaution.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations regarding controlled substances before travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with panic disorder
She was started on this medicine after experiencing frequent panic attacks. Within the first week, the clonazepam component helped reduce the intensity of attacks, and after a month, the escitalopram component stabilized her mood. She was advised to avoid alcohol and to attend regular follow-ups. She gradually tapered off clonazepam under supervision after six months.
💡 Lesson: Combination therapy can provide rapid relief while the antidepressant builds up, but gradual tapering of the benzodiazepine is essential.
👤 A 45-year-old man with generalized anxiety disorder and insomnia
He was prescribed this medicine for persistent worry and poor sleep. He initially felt drowsy during the day but adjusted after two weeks. His anxiety improved significantly, and his sleep quality enhanced. He was cautioned not to stop the medicine suddenly and to report any mood changes.
💡 Lesson: Initial side effects like drowsiness often subside, but adherence to the prescribed schedule and regular monitoring are key to safe use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Clonazepam starts working within 30-60 minutes, while escitalopram takes 1-2 weeks for initial effects and 4-6 weeks for full benefits.

Q: Can I stop taking this medicine suddenly?

A: No, stopping suddenly can cause withdrawal symptoms and relapse. Always taper gradually under medical supervision.

Q: Is it safe to take during pregnancy?

A: Both components may pose risks to the fetus. Consult your doctor if you are pregnant or planning pregnancy.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if it's not almost time for your next dose. Otherwise, skip it and continue your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • How do I stop this medicine safely?

🔄 Substitutes for citajoy c 0.5 mg/5 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a sleeping pill.
    Fact: It is primarily used for anxiety disorders, though it may cause drowsiness.
  • Myth: You can stop this medicine once you feel better.
    Fact: Stopping suddenly can cause withdrawal symptoms and relapse. Always taper under medical supervision.
  • Myth: This medicine is addictive for everyone.
    Fact: Clonazepam can cause dependence, but the risk is managed with proper prescribing and monitoring.

🔄 Alternative Options

Generic Alternatives

  • Clonazepam 0.5 mg + Escitalopram 5 mg tablet (generic)

Brand Alternatives

  • Azjoy Plus 0.5mg/5mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Clonazepam 0.5 mg + Escitalopram 5 mg","onset":"30-60 min (clonazepam)","duration":"6-12 hours (clonazepam)"},{"medicine":"Clonazepam alone","composition":"Clonazepam 0.5 mg","onset":"30-60 min","duration":"6-12 hours"},{"medicine":"Escitalopram alone","composition":"Escitalopram 5 mg","onset":"1-2 weeks","duration":"Continuous"}]

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