Cisblok 10mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or apnea
- Severe hypotension unresponsive to fluids
- Signs of anaphylaxis (rash, swelling, difficulty breathing)
- Prolonged muscle paralysis beyond expected duration
- Seizures or unexplained neurological symptoms
- Chest pain or arrhythmias
If experiencing severe symptoms, call emergency services immediately.
What is cisartacil 10mg injection used for?
This medicine is a neuromuscular blocking agent used during surgery and mechanical ventilation to relax muscles. It is given intravenously by healthcare professionals in a hospital setting.
- Generic Name: Cisatracurium
- Manufacturer: Neon Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cisartacil 10mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सिसैट्राक्यूरियम 10 मिलीग्राम इंजेक्शन के रूप में उपलब्ध है और इसका उपयोग सर्जरी के दौरान मांसपेशियों को शिथिल करने और मशीन से सांस देने में मदद के लिए किया जाता है। यह केवल अस्पताल में प्रशिक्षित डॉक्टरों द्वारा ही दी जाती है। यह दवा नस के माध्यम से दी जाती है और इसका असर 2-3 मिनट में शुरू होता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में रक्तचाप में कमी, चेहरे पर लालिमा और हृदय गति में कमी शामिल हैं। गंभीर दुष्प्रभावों में लंबे समय तक मांसपेशियों में पक्षाघात, सांस लेने में कठिनाई और एलर्जी प्रतिक्रिया हो सकती है। इनका प्रबंधन अस्पताल में डॉक्टरों द्वारा किया जाता है।
सुरक्षा सलाह: यह दवा केवल अस्पताल में प्रशिक्षित स्वास्थ्य पेशेवरों द्वारा ही दी जानी चाहिए। इस दवा को देने से पहले और बाद में मरीज की निगरानी आवश्यक है। मरीज को अपनी एलर्जी और स्वास्थ्य स्थिति के बारे में डॉक्टर को बताना चाहिए। इस दवा को घर पर स्वयं न लें।
💊 cisartacil 10mg injection Uses & Benefits
[{"condition":"Surgical muscle relaxation","description":"Used to provide skeletal muscle relaxation during surgical procedures, including abdominal, orthopedic, and cardiac surgeries.","evidence":"Well-established"},{"condition":"Mechanical ventilation in intensive care","description":"Facilitates endotracheal intubation and mechanical ventilation in critically ill patients by inducing paralysis.","evidence":"Well-established"},{"condition":"Endotracheal intubation","description":"Used to relax vocal cords and skeletal muscles to aid in placing an endotracheal tube.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Management of tetanus-induced muscle spasms","description":"Occasionally used in intensive care to control severe muscle spasms associated with tetanus.","evidence":"Limited"},{"condition":"Treatment of severe spasticity in neuromuscular disorders","description":"Rarely used off-label for short-term management of severe spasticity when other treatments fail.","evidence":"Limited"}]
Primary treatment for: Surgical procedures requiring muscle relaxation
Also treats: Mechanical ventilation, Endotracheal intubation
📋 Drug Information
| Generic Name(s) | Cisatracurium |
| Brand Name | Cisatra Injection |
| Manufacturer | Neon Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Skeletal muscle relaxant- Peripherally acting |
| Route of Administration | Intravenous |
| Storage | Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Once removed from refrigeration, it should be used within 24 hours. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a non-depolarizing neuromuscular blocking agent that acts by competitively antagonizing acetylcholine at nicotinic receptors on the motor endplate of skeletal muscle. By binding to these receptors, it prevents acetylcholine from depolarizing the muscle membrane, thereby inhibiting muscle contraction. This results in flaccid paralysis. The effect is reversible with acetylcholinesterase inhibitors such as neostigmine.
Mechanism Steps
💡 How to Take cisartacil 10mg injection
Strength: Injection: 10 mg in a single-use vial.
Dosage Information
| Adult Dosage | The dose of this medicine must be individualized by a qualified clinician based on the patient's weight, clinical condition, and the desired depth and duration of neuromuscular blockade. A typical intubating dose is 0.15 mg/kg administered intravenously over 5 to 10 seconds. Maintenance doses of 0.03 mg/kg may be given as needed. For continuous infusion, the rate is typically 1 to 3 mcg/kg/min. Dose adjustments are required for elderly patients and those with renal or hepatic impairment. This information is for educational purposes only and does not replace clinical judgment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have a slower onset and prolonged duration of action. Doses should be individualized and titrated carefully. |
| Renal Impairment | No specific dose adjustment is required for renal impairment, but prolonged neuromuscular blockade may occur due to active metabolites. Monitor closely. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment, as metabolism is independent of liver function. However, monitor closely. |
| Maximum Daily Dose | Not established from the available information. Dosing is individualized and titrated to effect. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cisartacil 10mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Gentamicin | Major | |
| Magnesium sulfate | Major | |
| Isoflurane | Major | |
| Furosemide | Moderate | |
| Verapamil | Moderate | |
| Corticosteroids | Minor |
🚨 Major Interactions
- Aminoglycoside antibiotics (e.g., gentamicin)
- Magnesium sulfate
- Inhalational anesthetics (e.g., isoflurane)
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Calcium channel blockers
🍷 Alcohol Interaction
No known direct interaction, but alcohol may enhance central nervous system depression. Use with caution in the perioperative period.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to cisatracurium or any component of the formulation","Inability to provide adequate ventilatory support","Lack of resuscitation equipment"]
⚠️ Warnings & Precautions
["Administer only by trained healthcare professionals.","Ensure adequate ventilation and oxygenation.","Use with caution in patients with neuromuscular disorders (e.g., myasthenia gravis).","Use with caution in patients with cardiovascular disease.","Use with caution in patients with renal or hepatic impairment.","May cause histamine release; monitor for signs of anaphylaxis."]
🤱 Lactation Safety
Not established from the available information. Consult a healthcare provider before use in breastfeeding mothers.
💊 Overdose Management
Overdose can lead to prolonged neuromuscular blockade and respiratory paralysis. Management includes maintaining a patent airway, providing mechanical ventilation, and administering acetylcholinesterase inhibitors (e.g., neostigmine) once neuromuscular function begins to recover. Continuous monitoring is essential until full recovery.
⏰ Missed Dose
This medicine is administered by healthcare professionals in a controlled setting. Missed doses are not applicable.
Additional Safety Advice
This medicine must only be administered by trained healthcare professionals in a setting equipped for intubation, artificial ventilation, and cardiovascular resuscitation. Continuous monitoring of neuromuscular function, heart rate, blood pressure, and oxygen saturation is essential during and after administration. The dose must be carefully adjusted based on the patient's condition, age, weight, and organ function. This medicine should not be used outside of a hospital or surgical center. Patients should inform their doctor of any allergies, especially to muscle relaxants, and of any history of neuromuscular disorders, cardiovascular disease, or renal or hepatic impairment. Do not attempt to self-administer this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have a slower onset and prolonged duration of action. Doses should be individualized and titrated carefully.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. The safety of this medicine in pregnancy is not well established.
🏥 Post-Surgery Considerations
After surgery, you will be monitored until the effects of this medicine wear off. Do not attempt to get up or drive until cleared by your doctor.
🦷 Dental Procedures
This medicine is not typically used in dental procedures. If you have dental work planned, inform your dentist about any recent use of muscle relaxants.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting until fully recovered from muscle relaxation and anesthesia. Consult your doctor before resuming exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
Do not drive or operate machinery until fully recovered from anesthesia and muscle relaxation. The effect of this medicine may impair your ability to perform tasks requiring alertness.
🛑 When to Stop This Medicine
This medicine is stopped by the healthcare professional once the procedure is complete or when muscle relaxation is no longer needed. Do not attempt to stop or adjust the dose yourself.
📅 Long-Term Use Effects
Prolonged use of this medicine, especially in intensive care settings, may lead to muscle weakness and prolonged paralysis. Monitoring and dose adjustment are essential to minimize these risks. Long-term effects are not well established for short-term use.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Alternatives like rocuronium or vecuronium may be used depending on the clinical scenario.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor regarding vaccination timing around surgical procedures.
📦 Storage Guide
✅ DO
Store refrigerated at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Protect from light
❌ DON'T
Do not use if solution is discolored or contains particles
✅ DO
Use within 24 hours after removal from refrigeration
❌ DON'T
Do not store at room temperature for prolonged periods
✈️ Traveling with This Medicine
This medicine is administered only in hospital settings and is not for self-administration. Patients do not need to carry it during travel. If you are traveling after a procedure where this medicine was used, ensure you have a copy of your medical records and inform your doctor about any residual muscle weakness. Follow your doctor's advice regarding activity restrictions.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 2-3 minutes after intravenous administration.
A: The muscle relaxation typically lasts 30-45 minutes for a standard dose, but this can vary based on dose and patient factors.
A: No, this medicine paralyzes the breathing muscles, so you will need mechanical ventilation until the effect wears off or is reversed.
A: Pediatric dosing is not established from available information. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for cisartacil 10mg injection
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Cisatracurium is a painkiller.
Fact: Cisatracurium is a muscle relaxant and does not provide pain relief or sedation. - Myth: Cisatracurium can be taken at home.
Fact: Cisatracurium must only be administered by trained professionals in a hospital setting.
🔄 Alternative Options
Generic Alternatives
- Cisatracurium besylate
Brand Alternatives
- Cisblok 10mg injection