cinzan plus tablet - Cinnarizine (20mg) + Dimenhydrinate (40mg) medicine

Dizitac Tablet: Complete Guide to Uses, Dosage, Side Effects, and Safety

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🏭 FDC Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, itching, swelling of face, lips, or throat, difficulty breathing)
  • Unusual muscle stiffness, tremors, or difficulty with movement
  • Seizures
  • Yellowing of skin or eyes (jaundice)
  • Severe drowsiness or confusion
  • Irregular heartbeat or palpitations
  • Difficulty urinating

If experiencing severe symptoms, call emergency services immediately.

What is cinzan plus tablet used for?

This medicine is a combination of cinnarizine and dimenhydrinate used to treat motion sickness, vertigo, and nausea. It works by blocking calcium channels and histamine receptors to reduce dizziness and vomiting. It is usually taken 1 tablet up to 3 times daily as prescribed.

  • Generic Name: Cinnarizine + Dimenhydrinate
  • Manufacturer: FDC Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cinzan plus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सिनारिज़िन और डाइमेनहाइड्रिनेट का संयोजन है, जिसका उपयोग चक्कर आना, उल्टी और मोशन सिकनेस के इलाज के लिए किया जाता है। यह आंतरिक कान की समस्याओं जैसे वर्टिगो और मेनियर रोग में भी प्रभावी है। यह दवा मतली और उल्टी को नियंत्रित करने में मदद करती है और चक्कर आने की भावना को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, धुंधली दृष्टि और थकान शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी पेट खराब, कब्ज या पेशाब करने में कठिनाई हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई या मांसपेशियों में अकड़न हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से खुराक न बढ़ाएं या घटाएं। इस दवा को लेने के बाद गाड़ी चलाने या भारी मशीनरी चलाने से बचें, क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको पार्किंसन रोग, निम्न रक्तचाप, या गुर्दे/यकृत की समस्या है, तो डॉक्टर को बताएं। इस दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 cinzan plus tablet Uses & Benefits

[{"condition":"Motion sickness","description":"Prevents and treats nausea, vomiting, and dizziness associated with travel by car, boat, or plane.","evidence":"Well-established"},{"condition":"Vertigo","description":"Relieves spinning sensation and imbalance caused by inner ear disorders.","evidence":"Well-established"},{"condition":"Meniere's disease","description":"Helps control vertigo, tinnitus, and hearing loss associated with this inner ear condition.","evidence":"Moderate"},{"condition":"Nausea and vomiting","description":"Controls nausea and vomiting from various causes, including chemotherapy and postoperative nausea.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, especially in patients with vertigo.","evidence":"Limited"},{"condition":"Anxiety-related dizziness","description":"May be used off-label to reduce dizziness associated with anxiety disorders.","evidence":"Limited"}]

Primary treatment for: Motion sickness

Also treats: Vertigo, Meniere's disease, Nausea and vomiting

📋 Drug Information

Generic Name(s)Cinnarizine + Dimenhydrinate
Brand NameAnset CD 20mg/40mg Tablet
ManufacturerFDC Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAntivertigo, Antiemetic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid driving or operating heavy machinery after taking this medicine.
3
Do not drink alcohol while taking this medicine.
4
Take the tablet 30 minutes before travel if using for motion sickness.
5
Do not exceed the prescribed dose.
6
Consult your doctor if symptoms persist beyond 7 days.
7
Inform your doctor if you have Parkinson's disease or glaucoma.
8
Use with caution in elderly patients due to increased risk of falls.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Motion sickness
This medicine is commonly prescribed for this.
Likely Use
✅
Vertigo
This medicine is effective for vertigo.
Likely Use
✅
Nausea and vomiting
This medicine helps control nausea and vomiting.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not primarily used for headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBoth cinnarizine and dimenhydrinate are well absorbed from the gastrointestinal tract after oral administration. Food may slightly delay absorption but does not significantly affect the extent of absorption.
DistributionCinnarizine is widely distributed in body tissues, including the central nervous system. Dimenhydrinate is also distributed throughout the body, crossing the blood-brain barrier and placenta.
Protein BindingCinnarizine is approximately 91% bound to plasma proteins. Dimenhydrinate is about 98% bound to plasma proteins.
MetabolismCinnarizine is extensively metabolized in the liver by CYP2D6 and CYP3A4 enzymes. Dimenhydrinate is metabolized in the liver to diphenhydramine and 8-chlorotheophylline.
Half-LifeThe elimination half-life of cinnarizine is approximately 3-6 hours. The half-life of dimenhydrinate is about 3.5-6 hours.
ExcretionBoth drugs and their metabolites are primarily excreted in the urine and feces.
BioavailabilityThe oral bioavailability of cinnarizine is approximately 60-70%. The bioavailability of dimenhydrinate is about 50-60%.
Onset of ActionThe onset of action is typically within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 1 to 2 hours for cinnarizine and 1 to 2 hours for dimenhydrinate.
Duration of ActionThe effects of this medicine last for approximately 4 to 6 hours, but may vary depending on the individual.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Cinnarizine is a calcium channel blocker that inhibits calcium influx into cells of the inner ear and brain, reducing vestibular stimulation and preventing dizziness. Dimenhydrinate is an antihistamine that blocks H1 receptors and also has anticholinergic properties, which reduce nausea and vomiting by acting on the vomiting center in the brain and on the vestibular apparatus. Together, they provide relief from vertigo, nausea, and vomiting.

Mechanism Steps

1
Calcium channel blockade by cinnarizine: Cinnarizine blocks T-type calcium channels in the inner ear and brain, reducing calcium influx and decreasing vestibular hair cell excitability.
2
Histamine H1 receptor blockade by dimenhydrinate: Dimenhydrinate competes with histamine for H1 receptors in the vomiting center and vestibular nucleus, reducing nausea and vomiting.
3
Anticholinergic action of dimenhydrinate: Dimenhydrinate also blocks muscarinic acetylcholine receptors, which contributes to its antiemetic and antivertigo effects.
4
Combined effect: The combined action of both ingredients provides rapid and effective relief from vertigo, nausea, and vomiting.

💡 How to Take cinzan plus tablet

Strength: Each tablet contains cinnarizine 20 mg and dimenhydrinate 40 mg.

1Take this medicine by mouth with a glass of water.
2You can take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole. Do not crush, chew, or break it.
4Take it at the same time each day if prescribed regularly.
5For motion sickness, take it 30 minutes before travel.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is 1 tablet taken orally up to 3 times daily, depending on the condition being treated. For motion sickness, take 1 tablet 30 minutes before travel. For vertigo, the dose may be 1 tablet 2-3 times daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, confusion, and movement disorders. Use with caution and lower doses may be required. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dose adjustment guidelines are available. Use with caution in patients with renal impairment. Consult your doctor.
Hepatic ImpairmentNo specific dose adjustment guidelines are available. Use with caution in patients with hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets (60 mg cinnarizine + 120 mg dimenhydrinate) in divided doses. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and dizziness.
Grapefruit juice
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cinzan plus tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If drowsiness persists, consult your doctor.
Dry mouth (Common (5-10%))
Sip water frequently or chew sugarless gum. Consult doctor if severe.
Blurred vision (Common (5-10%))
Usually temporary. Avoid driving if vision is affected. Consult doctor if persistent.
Fatigue (Common (5-10%))
Get adequate rest. Consult doctor if fatigue interferes with daily activities.
Stomach upset (Uncommon (1-5%))
Take with food or milk to reduce stomach upset. Consult doctor if it continues.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Movement disorders (extrapyramidal symptoms) (Rare (<0.1%))
Report any unusual muscle stiffness, tremors, or difficulty with movement to your doctor immediately.
Blood dyscrasias (Very rare (<0.01%))
Report any unusual bruising, bleeding, or signs of infection to your doctor.
Seizures (Very rare (<0.01%))
Seek emergency medical help if seizures occur.

⚠️ Rare Side Effects

Hallucinations
Contact your doctor immediately if you experience hallucinations.
Jaundice
Report yellowing of skin or eyes to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Benzodiazepines Major
MAO inhibitors Major
Tricyclic antidepressants Moderate
Fluoxetine Moderate
Paroxetine Moderate
Antacids Minor
Opioids Major
Atropine Moderate
Grapefruit juice Moderate

🚨 Major Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • MAO inhibitors

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to drive or operate machinery. It may also increase the risk of other side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to cinnarizine, dimenhydrinate, or any component of the formulation","Parkinson's disease","Severe hypotension","Acute porphyria","Children under 12 years of age"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Use with caution in patients with glaucoma, urinary retention, or prostatic hyperplasia.","Do not use for longer than recommended without medical supervision.","May impair ability to perform tasks requiring alertness."]

🤱 Lactation Safety

Not established from the available information. It is not known if this medicine passes into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, hallucinations, seizures, and respiratory depression. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Do not drink alcohol while taking this medicine, as it can increase drowsiness and dizziness. Inform your doctor if you have Parkinson's disease, low blood pressure, liver or kidney problems, or if you are pregnant or breastfeeding. Do not take this medicine for longer than recommended without medical advice. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, confusion, and movement disorders. Use with caution and lower doses may be required. Regular monitoring for falls and extrapyramidal symptoms is recommended.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

This medicine may be used for postoperative nausea and vomiting, but it can increase sedation when combined with other sedatives. Inform your anesthesiologist if you are taking this medicine before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with sedatives or anesthetics used during dental procedures. It may also cause dry mouth, which can affect dental health.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your body.
🥗
Stay hydrated throughout the day.
😴
Get adequate sleep to help manage vertigo.
💧
Avoid sudden head movements that can trigger dizziness.
🧘
Practice relaxation techniques to reduce stress.
🌞
Limit caffeine and alcohol intake.

🏋️ Exercise Considerations

Avoid exercises that require balance or rapid movements, such as running or cycling, until you know how this medicine affects you. Dizziness and drowsiness may increase the risk of falls. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Eat small, frequent meals to manage nausea.
Include ginger in your diet as it may help with nausea.
Stay well hydrated with water and clear fluids.
Avoid spicy and greasy foods that can upset your stomach.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves operating heavy machinery.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. For short-term use, such as for motion sickness, you can stop after the journey. For long-term use, your doctor will advise when to stop.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to movement disorders such as tremors, muscle stiffness, and tardive dyskinesia, especially in elderly patients. Regular monitoring by a doctor is recommended. It may also cause blood dyscrasias in rare cases. Do not use for prolonged periods without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy for vertigo

Vestibular rehabilitation exercises can help manage vertigo.

Evidence: Well-established
Acupuncture

May help reduce nausea and vomiting.

Evidence: Moderate
Ginger supplements

Natural remedy for nausea.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust the timing of doses gradually. For motion sickness, take the tablet 30 minutes before travel. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with frequent motion sickness during travel
She used to feel nauseous and dizzy every time she traveled by car. Her doctor prescribed this medicine to take 30 minutes before travel. She noticed significant relief and could travel comfortably. She was advised to avoid driving after taking the medicine.
💡 Lesson: Taking the medicine before travel and avoiding driving can make journeys comfortable and safe.
👤 A 60-year-old man with vertigo due to Meniere's disease
He experienced spinning sensations and imbalance. His doctor prescribed this medicine twice daily. After a few days, his vertigo episodes reduced. He was monitored for drowsiness and advised to rise slowly from sitting or lying positions.
💡 Lesson: Regular use as prescribed and monitoring for side effects helps manage vertigo effectively.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it.

Q: Can I take this medicine on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to drive after taking this medicine?

A: This medicine may cause drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.

Q: Can I take this medicine with alcohol?

A: No, alcohol should be avoided as it can increase drowsiness and dizziness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with other antihistamines?

🔄 Substitutes for cinzan plus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any type of dizziness.
    Fact: This medicine is specifically for vertigo and motion sickness. It may not be effective for dizziness caused by other conditions.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.
  • Myth: You can drink alcohol while taking this medicine.
    Fact: Alcohol increases the sedative effects and should be avoided.

🔄 Alternative Options

Generic Alternatives

  • Cinnarizine + Dimenhydrinate combination tablets from other manufacturers

Brand Alternatives

  • Dizitac
  • Vertin
  • Dramamine
  • Stugeron

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Cinnarizine + Dimenhydrinate","primary_use":"Motion sickness, vertigo","onset":"30-60 min","duration":"4-6 hours"},{"medicine":"Cinnarizine alone","active_ingredients":"Cinnarizine","primary_use":"Vertigo, motion sickness","onset":"30-60 min","duration":"4-6 hours"},{"medicine":"Dimenhydrinate alone","active_ingredients":"Dimenhydrinate","primary_use":"Motion sickness, nausea","onset":"30-60 min","duration":"4-6 hours"},{"medicine":"Meclizine","active_ingredients":"Meclizine","primary_use":"Vertigo, motion sickness","onset":"1 hour","duration":"8-24 hours"}]

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