cinpar 37.5mg tablet cr

4.4 (19 reviews)

Paroxetine (37.5mg)

🏭 Cinerea Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is cinpar 37.5mg tablet cr used for?

Aroximat CR 12.5 Tablet (Paroxetine) is used to treat NEURO CNS. It contains Paroxetine (37.5mg), which Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the. Always consult your doctor before use. Take as prescribed.

Generic Name: Paroxetine
Manufacturer: Cinerea Biotech Pvt Ltd
Form: Allopathy
Pregnancy Category: D
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cinpar 37.5mg tablet cr Uses & Benefits

Major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, post-traumatic stress disorder.

Off-label uses: Premenstrual dysphoric disorder, hot flashes, premature ejaculation.

📋 Drug Information

Generic Name(s)	Paroxetine
Brand Name	Aroximat CR 12.5 Tablet
Manufacturer	Cinerea Biotech Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Selective Seretonin Reuptake inhibitors (SSRIs)
Route of Administration	Oral.
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; food does not significantly affect absorption.

DistributionWidely distributed in the body; crosses the blood-brain barrier.

Protein BindingApproximately 95% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP2D6 and other enzymes.

Half-LifeAbout 21 hours (range 3-65 hours).

ExcretionPrimarily excreted in urine (64%) and feces (36%).

BioavailabilityAbout 50-100% (mean 86%).

Onset of Action1-2 weeks for therapeutic effect.

Peak Plasma Time5-6 hours (controlled-release formulation).

Duration of Action24 hours.

How It Works

Selective serotonin reuptake inhibitor (SSRI); increases serotonin levels in the synaptic cleft.

Mechanism Steps

1Paroxetine binds to the serotonin transporter (SERT) on presynaptic neurons.

2Inhibits reuptake of serotonin into the presynaptic neuron.

3Increases serotonin concentration in the synaptic cleft.

💡 How to Take cinpar 37.5mg tablet cr

Follow your doctor's prescription exactly.

⚠️ Side Effects of cinpar 37.5mg tablet cr

✅ Common Side Effects

Nausea
Drowsiness
Dizziness
Insomnia
Dry mouth
Constipation
Sexual dysfunction

🚨 Serious Side Effects

Serotonin syndrome
Suicidal thoughts
Bleeding
Seizures
Hyponatremia

⚠️ Rare Side Effects

Priapism
Angle-closure glaucoma
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
MAOIs	Major	Risk of serotonin syndrome
Warfarin	Moderate	Increased bleeding risk
NSAIDs	Moderate	Increased bleeding risk
Cimetidine	Moderate	Increased paroxetine levels
Tamoxifen	Moderate	Reduced tamoxifen efficacy

🚨 Major Interactions

MAOIs
Pimozide
Thioridazine
Linezolid
Methylene Blue

⚡ Moderate Interactions

Warfarin
NSAIDs
Aspirin
Cimetidine
Flecainide
Propafenone
Tamoxifen

ℹ️ Minor Interactions

Digoxin
Theophylline
Lithium

🍽️ Food Interactions

Grapefruit juice may increase paroxetine levels.

🍷 Alcohol Interaction

Avoid alcohol; may increase CNS depression.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity, concurrent MAOI use, pregnancy (especially third trimester), lactation.

📊 Monitoring Parameters

Suicidal ideation, serotonin syndrome symptoms, liver function, renal function.

🤱 Lactation Safety

Not recommended; excreted in breast milk.

💊 Overdose Management

Activated charcoal, supportive care; serotonin syndrome management.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip if close.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for cinpar 37.5mg tablet cr

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Alternative brands with exact same active ingredient (Paroxetine (37.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.