Arbitel-Trio 25 Tablet ER: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Difficulty breathing or wheezing
- Chest pain or tightness
- Slow or irregular heartbeat
- Swelling of face, lips, or throat
- Sudden weight gain or swelling in legs
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is cilory m 10mg/25mg tablet used for?
This medicine is a combination of Cilnidipine and Metoprolol Succinate used to treat high blood pressure. It works by relaxing blood vessels and slowing the heart rate.
- Generic Name: Cilnidipine + Metoprolol Succinate
- Manufacturer: Med Manor Organics Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cilory m 10mg/25mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह दिल के दौरे और स्ट्रोक के जोखिम को कम करने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, और टखनों में सूजन शामिल हैं। कुछ रोगियों को धीमी हृदय गति, ठंडे हाथ-पैर, या पेट की परेशानी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि सांस लेने में कठिनाई, गंभीर चक्कर, या चेहरे और गले में सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। शराब का सेवन न करें क्योंकि इससे चक्कर और रक्तचाप कम हो सकता है। यदि आपको अस्थमा, मधुमेह, या गुर्दे/यकृत की बीमारी है तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप और हृदय गति की जांच कराएं।
💊 cilory m 10mg/25mg tablet Uses & Benefits
[{"condition":"Essential Hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Angina Pectoris","description":"It may be used to prevent chest pain (angina) by reducing heart rate and improving blood flow to the heart.","evidence":"Moderate"},{"condition":"Heart Rate Control","description":"Metoprolol Succinate component helps control fast heart rates in conditions like atrial fibrillation.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine Prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Anxiety with Palpitations","description":"May be used off-label to manage physical symptoms of anxiety such as rapid heartbeat.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina, Heart Failure (stable), Atrial Fibrillation
📋 Drug Information
| Generic Name(s) | Cilnidipine + Metoprolol Succinate |
| Brand Name | Arbitel-Trio 50 Tablet ER |
| Manufacturer | Med Manor Organics Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive combination (Calcium channel blocker + Beta-blocker) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Cilnidipine is a dual L-type and N-type calcium channel blocker. It blocks calcium entry into vascular smooth muscle cells, causing vasodilation and reducing peripheral vascular resistance. Additionally, it blocks N-type calcium channels in sympathetic nerve endings, reducing norepinephrine release, which further lowers blood pressure and heart rate. Metoprolol Succinate is a cardioselective beta-1 adrenergic receptor blocker. It reduces heart rate, myocardial contractility, and cardiac output, thereby lowering blood pressure and myocardial oxygen demand. Together, they provide effective blood pressure control with reduced reflex tachycardia.
Mechanism Steps
💡 How to Take cilory m 10mg/25mg tablet
Strength: Tablet containing Cilnidipine 10 mg and Metoprolol Succinate 25 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a low dose and monitor closely for hypotension and bradycardia. |
| Renal Impairment | No specific dose adjustment is established for mild to moderate renal impairment. Use with caution in severe renal impairment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Cilnidipine 10 mg + Metoprolol Succinate 25 mg) once daily. Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cilory m 10mg/25mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| MAOIs | Major | |
| Ketoconazole | Moderate | |
| Fluoxetine | Moderate | |
| NSAIDs | Moderate | |
| Antacids | Minor | |
| Grapefruit Juice | Minor |
🚨 Major Interactions
- Verapamil or Diltiazem
- Clonidine
- Monoamine Oxidase Inhibitors (MAOIs)
⚡ Moderate Interactions
- CYP3A4 Inhibitors (e.g., Ketoconazole, Ritonavir)
- CYP2D6 Inhibitors (e.g., Fluoxetine, Paroxetine)
- NSAIDs
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, or falls. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe asthma or chronic obstructive pulmonary disease (COPD)","Second or third-degree heart block","Severe bradycardia (heart rate < 50 bpm)","Cardiogenic shock","Decompensated heart failure","Hypersensitivity to Cilnidipine or Metoprolol Succinate"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly; taper gradually under medical supervision.","Use with caution in patients with diabetes, as Metoprolol may mask hypoglycemia symptoms.","May worsen symptoms of peripheral vascular disease.","Use with caution in patients with liver or kidney impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Both Cilnidipine and Metoprolol Succinate are excreted in breast milk. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause severe hypotension, bradycardia, heart failure, or bronchospasm. Seek immediate medical attention. Treatment is supportive and symptomatic, including activated charcoal, IV fluids, atropine for bradycardia, and vasopressors if needed.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as abrupt withdrawal of Metoprolol can worsen angina or lead to a heart attack. Avoid alcohol while taking this medicine, as it can increase dizziness and lower blood pressure further. Inform your doctor if you have asthma, diabetes, liver or kidney disease, or any heart condition. Regular monitoring of blood pressure, heart rate, and kidney function is advised. Do not drive or operate heavy machinery until you know how this medicine affects you. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a low dose and monitor closely for dizziness and falls.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. This medicine may not be safe during pregnancy. Alternative treatments may be recommended.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect heart rate and blood pressure during surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may interact with certain local anesthetics containing epinephrine. Monitor blood pressure during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid sudden strenuous activities as this medicine can cause dizziness or slow heart rate. Stay hydrated and warm up gradually.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with dose adjustment.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, your doctor may adjust the dose or switch to another medicine. Abrupt withdrawal can worsen angina or cause heart attack.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing hypertension. Regular monitoring of blood pressure, heart rate, and renal function is recommended. Metoprolol may mask symptoms of hypoglycemia in diabetics. Cilnidipine may have renoprotective effects. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help control blood pressure.
Evidence: Well-establishedYour doctor may prescribe alternative combinations if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but full effect may take 1-2 weeks. Regular monitoring is important.
A: No, hypertension is a chronic condition. Stopping this medicine suddenly can cause rebound hypertension or heart problems. Always consult your doctor before stopping.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for cilory m 10mg/25mg tablet
View AllAlternative brands with exact same active ingredient:
-
StayHappi Cilnidipine+Metoprolol Succinate 10mg/25mg TabletSarvagunaushdhi Pvt Ltd ₹52.09 40.1% CHEAPER
-
cadmet trio tabletLividus Pharmaceuticals Pvt Ltd ₹65.63 24.6% CHEAPER
-
ibcil m 10mg/25mg tablet erIndiabulls pharmaceutical ltd ₹70.31 19.2% CHEAPER
-
metotric c 10mg/25mg tablet erCadbless Life Care ₹79.69 8.4% CHEAPER
-
ccbest m 10mg/25mg tabletKepler Health Care ₹80.63 7.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: Hypertension is a chronic condition. Stopping this medicine suddenly can cause rebound hypertension or heart problems. Always consult your doctor before stopping. - Myth: This medicine causes kidney damage.
Fact: This medicine is used to protect the kidneys in hypertensive patients. However, regular monitoring is advised.
🔄 Alternative Options
Generic Alternatives
- Cilnidipine + Metoprolol Succinate generic tablets
Brand Alternatives
- Arbitel-Trio 25 Tablet ER