cilnilor t 10mg/40mg tablet - Cilnidipine (10mg) + Telmisartan (40mg) medicine

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🏭 Baylor Pharmaceutical Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. This medicine may cause harm to the fetus. Consult your doctor for alternative treatments if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing
  • Chest pain or irregular heartbeat
  • Decreased urine output or swelling in legs
  • Yellowing of skin or eyes
  • Severe headache with visual changes

If experiencing severe symptoms, call emergency services immediately.

What is cilnilor t 10mg/40mg tablet used for?

This medicine is a combination of Cilnidipine and Telmisartan used to treat high blood pressure. It works by relaxing blood vessels and blocking a hormone that narrows them, leading to reduced blood pressure.

  • Generic Name: Cilnidipine + Telmisartan
  • Manufacturer: Baylor Pharmaceutical Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cilnilor t 10mg/40mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह सिल्निडिपिन और टेल्मिसार्टन का संयोजन है, जो रक्त वाहिकाओं को आराम देकर और रक्तचाप बढ़ाने वाले हार्मोन को रोककर रक्तचाप को कम करती है। यह दवा स्ट्रोक, दिल के दौरे और गुर्दे की समस्याओं के जोखिम को कम करने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान और पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और दवा के अभ्यस्त होने पर ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या बहुत कम रक्तचाप महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अपने आप बंद या कम न करें। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं और रक्तचाप और कम हो सकता है। उठते या बैठते समय धीरे-धीरे उठें। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो डॉक्टर को बताएं। नियमित रूप से रक्तचाप, गुर्दे की कार्यप्रणाली और पोटेशियम के स्तर की जांच कराएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cilnilor t 10mg/40mg tablet Uses & Benefits

[{"condition":"Essential hypertension","description":"This medicine is used to lower high blood pressure in adults, reducing the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Hypertension

Also treats: Chronic kidney disease, Diabetes mellitus, Heart failure

📋 Drug Information

Generic Name(s)Cilnidipine + Telmisartan
Brand NameAcmetel-LN Tablet
ManufacturerBaylor Pharmaceutical Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blocker + Angiotensin II receptor blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood pressure control.
2
Monitor your blood pressure regularly at home and keep a record to share with your doctor.
3
Avoid alcohol while taking this medicine as it can increase dizziness and low blood pressure.
4
Stand up slowly from sitting or lying positions to prevent dizziness.
5
Inform your doctor if you experience swelling of ankles or feet, as the dose may need adjustment.
6
Do not stop this medicine abruptly without consulting your doctor, even if you feel well.
7
Stay hydrated, especially during hot weather or exercise, to prevent low blood pressure.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Headache
This medicine is not a primary headache reliever; it may cause headache as a side effect.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCilnidipine is rapidly absorbed after oral administration, with peak plasma levels reached in 1-2 hours. Telmisartan is also rapidly absorbed, with peak levels in 0.5-1 hour. Food does not significantly affect the absorption of either component.
DistributionBoth drugs are highly protein-bound and distribute widely into tissues. Cilnidipine has a large volume of distribution. Telmisartan has a volume of distribution of approximately 500 L.
Protein BindingCilnidipine is approximately 95% bound to plasma proteins. Telmisartan is >99.5% bound to plasma proteins.
MetabolismCilnidipine is metabolized in the liver by CYP3A4. Telmisartan is metabolized minimally by conjugation to glucuronide; no CYP450 metabolism.
Half-LifeCilnidipine half-life is approximately 2-3 hours. Telmisartan half-life is approximately 24 hours.
ExcretionCilnidipine is excreted mainly in urine and feces. Telmisartan is excreted primarily in feces via bile, with less than 1% excreted unchanged in urine.
BioavailabilityCilnidipine bioavailability is approximately 13%. Telmisartan bioavailability is approximately 42%.
Onset of ActionBlood pressure lowering effect begins within 1-2 hours after oral administration.
Peak Plasma TimeCilnidipine: 1-2 hours; Telmisartan: 0.5-1 hour.
Duration of Action24 hours, allowing once-daily dosing.

How It Works

This medicine combines two antihypertensive agents with complementary actions. Cilnidipine blocks L-type and N-type calcium channels, leading to relaxation of arterial smooth muscle and reduced peripheral resistance. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release. The dual action results in more effective blood pressure reduction than either agent alone.

Mechanism Steps

1
Calcium channel blockade by Cilnidipine: Cilnidipine blocks L-type and N-type calcium channels in vascular smooth muscle, reducing calcium influx and causing vasodilation.
2
Angiotensin receptor blockade by Telmisartan: Telmisartan blocks AT1 receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release.
3
Additive blood pressure reduction: The combined effects reduce peripheral resistance and blood volume, leading to lower blood pressure.

💡 How to Take cilnilor t 10mg/40mg tablet

Strength: Cilnidipine 10 mg + Telmisartan 40 mg immediate-release tablet.

1Take this medicine orally with a glass of water.
2Swallow the tablet whole. Do not crush or chew.
3Take it at the same time each day, preferably in the morning.
4You can take it with or without food.
5Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with severe renal impairment. Dose adjustment may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet (Cilnidipine 10 mg + Telmisartan 40 mg) once daily. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time daily
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase cilnidipine levels.
High-potassium foods
Moderate intake
Telmisartan may increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with your regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cilnilor t 10mg/40mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you. Rise slowly from sitting or lying positions.
Fatigue (Common (5-10%))
Get adequate rest. Consult doctor if it interferes with daily activities.
Peripheral edema (swelling of ankles/feet) (Common (5-10%))
Elevate legs when sitting. Consult doctor if swelling is severe or persistent.
Flushing (Uncommon (1-5%))
Usually transient. Consult doctor if bothersome.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or blurred vision.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Hyperkalemia (high potassium) (Rare (<0.1%))
Seek medical attention if you experience muscle weakness, irregular heartbeat, or numbness.
Angioedema (Rare (<0.1%))
Seek emergency care if you develop swelling of face, lips, tongue, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Jaundice
Report yellowing of skin or eyes to your doctor immediately.
Severe allergic reactions
Seek emergency care if you develop rash, itching, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Potassium supplements Major
NSAIDs Major
Lithium Major
CYP3A4 inhibitors Moderate
CYP3A4 inducers Moderate
Grapefruit juice Minor

🚨 Major Interactions

  • Potassium supplements or potassium-sparing diuretics
  • NSAIDs
  • Lithium

⚡ Moderate Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
  • CYP3A4 inducers (e.g., rifampin, carbamazepine)

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to avoid alcohol or limit consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Severe liver impairment","Biliary obstructive disorders","History of angioedema with ARBs","Concomitant use with aliskiren in patients with diabetes"]

⚠️ Warnings & Precautions

["Avoid use in pregnancy. If pregnancy is detected, discontinue immediately.","Use with caution in patients with kidney artery stenosis.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol consumption.","Monitor potassium levels, especially if taking potassium supplements or potassium-sparing diuretics.","Use with caution in patients with liver disease.","Do not stop abruptly without consulting your doctor."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension, dizziness, and fainting. Seek immediate medical attention. Treatment is supportive and symptomatic. If taken recently, gastric lavage may be considered. Monitor vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without consulting your doctor. Avoid alcohol while taking this medicine as it can increase dizziness and lower blood pressure further. Stand up slowly from sitting or lying positions to prevent dizziness. Inform your doctor if you have kidney or liver problems, are pregnant, or planning to become pregnant. Regular monitoring of blood pressure, kidney function, and potassium levels is important. Keep all follow-up appointments.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Start with a lower dose and monitor closely. Regular monitoring of kidney function and electrolytes is important.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy as it may harm the fetus. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid low blood pressure during the procedure. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking, swimming, or cycling.
😴
Reduce salt intake to less than 5 grams per day.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep (7-8 hours per night).

🏋️ Exercise Considerations

Moderate exercise is generally safe and beneficial. However, avoid sudden strenuous activities, especially in hot weather, as they can cause dehydration and low blood pressure. Stay hydrated and listen to your body.

🥗 Diet Recommendations

Follow a DASH diet rich in fruits, vegetables, and whole grains.
Limit sodium intake.
Increase potassium-rich foods (unless advised otherwise).
Reduce saturated and trans fats.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with dose adjustment.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood pressure is well-controlled for a long period, your doctor may consider reducing or stopping the dose. Always follow medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe and effective for managing hypertension. Regular monitoring of blood pressure, kidney function, and electrolytes is recommended. Some patients may develop tolerance, requiring dose adjustment. It is important to continue lifestyle modifications alongside medication.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.

Evidence: Well-established
Other antihypertensive combinations

Your doctor may prescribe alternative combinations if this medicine is not suitable for you.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines to your destination.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension and diabetes
He was prescribed this medicine after his blood pressure remained high on a single drug. Within a few weeks, his blood pressure stabilized, and he felt more energetic. He experienced mild ankle swelling initially, which improved after his doctor adjusted his salt intake and advised leg elevation.
💡 Lesson: Combination therapy can be more effective for blood pressure control, but side effects like ankle swelling should be reported to the doctor for appropriate management.
👤 A 62-year-old woman with chronic kidney disease and hypertension
She started this medicine under close supervision. Her blood pressure improved, and her kidney function remained stable. She emphasized the importance of regular monitoring and taking the medicine at the same time every day.
💡 Lesson: With proper monitoring, this medicine can be used safely in patients with kidney disease, but regular follow-up is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but the full effect may take 1-2 weeks of regular use.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, you should not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause a dangerous rise.

Q: What should I do if I miss a dose?

A: If you remember within 12 hours, take it. If more than 12 hours have passed, skip it and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cilnilor t 10mg/40mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause a dangerous rise in blood pressure.
  • Myth: This medicine causes kidney damage.
    Fact: When used as prescribed and monitored, this medicine can actually protect the kidneys. Regular monitoring is important.

🔄 Alternative Options

Generic Alternatives

  • Cilnidipine + Telmisartan combination (generic)

Brand Alternatives

  • Cetanil T Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Cilnidipine + Telmisartan","composition":"Cilnidipine 10 mg + Telmisartan 40 mg","onset":"1-2 hours","duration":"24 hours","common_side_effects":"Headache, dizziness, edema"},{"medicine":"Amlodipine + Telmisartan","composition":"Amlodipine 5 mg + Telmisartan 40 mg","onset":"6-12 hours","duration":"24 hours","common_side_effects":"Edema, headache, flushing"}]

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